Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$230K - $260K *

Oversee regional sales strategies and lead a team to drive oncology product sales. Collaborate cross-functionally to enhance market insights and ensure compliance while fostering team development and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$201K - $251K *

Champion Quality governance by leading the development and management of Quality Agreements across global operations, ensuring compliance and effective partnerships with internal and external stakehol...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$70K - $120K *

Drive sales success by building relationships with dental professionals, promoting innovative products, and achieving targets. Leverage your expertise to deliver exceptional customer service and suppo...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and overseeing scientific content across multiple therapeutic areas, ensuring high-quality contributions and strategic client interactions to drive growth and innovation...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $124K *

Lead the charge in delivering impactful scientific software demonstrations and training. Collaborate with diverse teams to address customer needs and enhance bioinformatics solutions, driving innovati...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $181K *

Lead the charge in regional clinical study delivery, ensuring quality and compliance while managing timelines and budgets. Collaborate with teams and stakeholders to drive operational excellence and e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$118K - $158K *

Lead the charge in regional clinical study delivery, ensuring quality and compliance while managing timelines and budgets. Collaborate with stakeholders and oversee external partners to drive successf...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Elevate data operations by architecting AI-driven solutions that enhance resilience, scalability, and intelligence in data processing systems. Lead cross-functional teams to implement innovative DataO...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$175K - $210K *

Elevate your career by owning the sales cycle for major employers, building strategic partnerships, and driving innovative health programs that shape enterprise success and market presence...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $185K *

Join a dynamic team to define and lead product strategy for Family Building Navigation, enhancing member engagement through innovative digital experiences and personalized support while collaborating...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $125K *

Empower healthcare compliance by enhancing programs, mitigating risks, and driving operational integrity. Collaborate with diverse clients to deliver tailored solutions in a dynamic regulatory landsca...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Drive strategic relationships with Oncology departments, enhancing education on product benefits and risks. Collaborate with healthcare professionals to boost sales and market share while ensuring com...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive impactful solutions as you lead integration efforts, enhancing user experiences through collaboration and innovation while managing multiple complex projects and mentoring junior engineers...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$204K - $290K *

Elevate your career by driving strategic engagement with Key Opinion Leaders in oncology. Collaborate with cross-functional teams to enhance brand strategies and execute impactful marketing initiative...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion clinical monitoring and site management processes, ensuring compliance with protocols and regulations. Develop strong relationships with investigational sites while conducting thorough assess...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $112K *

Empower health transformation by leading a dynamic nursing team, driving operational excellence, and enhancing patient care through innovative practices and data-driven insights. Collaborate with inte...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $130K *

Join a team that's redefining billing solutions in the legal sector. Leverage your expertise in law firm financial operations to support sales efforts, conduct client demos, and enhance our innovative...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $236K *

Develop and implement innovative therapeutic approaches to enhance mental health outcomes. Collaborate across departments to evaluate, integrate, and govern emerging treatments, ensuring clinical feas...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $200K *

Drive compliance excellence by leading regulatory strategy and governance, ensuring scalable infrastructure for service contracts and insurance programs across North America. Collaborate with executiv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$192K - $214K *

Join us in shaping the patient marketing strategy for a leading biopharmaceutical asset. Collaborate across teams to enhance patient engagement and create impactful communications that resonate with p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$94K - $130K *

Elevate product outcomes by collaborating with teams to prioritize and define user stories, ensuring alignment with business needs while maximizing value delivery and maintaining product quality throu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$189K - $316K *

Transform the therapeutic landscape by leading execution in GMASE, ensuring high-quality clinical delivery at scale through a structured, AI-enabled framework that enhances collaboration across global...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$132K - $178K *

Optimize supplier quality oversight by leading cross-functional teams, ensuring compliance with global standards, and driving continuous improvement initiatives to enhance performance and mitigate ris...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.