Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$67K - $199K *

Lead NCQA Health Outcomes and Community-Focused Care Accreditation initiatives, driving quality improvement and compliance across health plans. Collaborate with teams to enhance equitable health outco...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $231K *

Join our dynamic Network team to lead complex projects, enhance provider experiences, and drive strategic initiatives. Collaborate with cross-functional teams to optimize network infrastructure and en...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $225K *

Lead the charge in enhancing inventory and supply chain systems through effective planning, optimization, and analytics. Drive technology choices while mentoring a team to ensure high-quality software...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Media

$247K - $309K *

Unlock potential by leading medical strategy for hematologic malignancies. Collaborate cross-functionally to drive evidence generation, stakeholder engagement, and launch readiness, ensuring impactful...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to enhancing patient care in cardiology. This role involves providing comprehensive support, education, and coordination for patients with cardiovascular conditions, ensur...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Elevate your career by preparing and analyzing complex Medicaid cost reports, ensuring compliance with regulations, and leading a team of accountants in a remote setting. Drive process improvements an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $344K *

Transform analytics modernization and productivity by leading strategy, governance, and process evolution. Collaborate with cross-functional teams to enhance workflows, drive AI adoption, and optimize...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Reimagine medical communication by leading a team of writers to craft regulatory and scientific documents. Oversee projects, ensuring clarity and quality for diverse audiences while adhering to timeli...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $250K *

Join a team that's dedicated to enhancing patient care by promoting innovative oncology solutions. You'll engage with healthcare professionals, drive product awareness, and leverage insights to streng...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Join a team that's dedicated to advancing oncology care by promoting innovative treatments, building strong relationships with healthcare professionals, and driving patient access to essential therapi...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Elevate patient care by driving oncology product success through strategic relationships and innovative solutions. Collaborate with key stakeholders to ensure timely access to therapies while exceedin...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$45K - $250K *

Transform your career by connecting healthcare professionals with meaningful roles. Join a supportive team focused on building relationships and driving results while enjoying unlimited earning potent...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $135K *

Engage in driving sales success within primary care and specialty biopharmaceuticals. Collaborate effectively to execute strategic business plans, achieve sales goals, and launch new products in a dyn...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $166K *

Unlock financial insights at a strategic level, driving value realization and governance for transformation investments. Collaborate across functions to enhance performance, support decision-making, a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to enhancing healthcare technology by developing and maintaining our Electronic Health Record platform using Ruby. Collaborate in an agile environment to deliver impactful...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join our team to drive innovation in eye care by presenting scientific insights, fostering relationships with medical experts, and influencing strategies to enhance patient outcomes through evidence-b...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $232K *

Unlock potential by leading legal reviews for promotional and medical materials. Collaborate across teams to ensure compliance and provide practical guidance in a fast-paced environment, supporting pr...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$121K - $155K *

Empower individuals by providing evidence-based mental health support to patients aged 13+. Collaborate with a dedicated clinical team in a fully remote environment, enhancing patient care and profess...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders. Collaborate with internal teams to enhance patient access and exceed performance goals while managing territory reso...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$205K - $228K *

Champion patient-focused initiatives by leading strategy and execution of ambassador programs. Build relationships with patients and advocacy groups to enhance engagement and ensure their voices shape...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the Community Living Center, overseeing patient care and safety. Collaborate with an interdisciplinary team to monitor productivity, drive strategic planning, and ensure compliance with quality s...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$113K - $226K *

Optimize customer relationships and educational programs in Cardiac Rhythm Management and Electrophysiology. Collaborate with teams to enhance product adoption and training initiatives, ensuring high...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.