Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$203K - $253K *

Strategize and lead patient advocacy and medical education initiatives, fostering collaboration with stakeholders to enhance patient engagement and inform Medical Affairs strategies. Drive impactful i...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Discover a pivotal role in driving commercial performance and patient access. Engage healthcare providers, build relationships, and support product launches while collaborating with cross-functional t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion efficiency in the revenue cycle as you lead a dedicated billing team. Drive performance improvements, oversee compliance, and identify revenue opportunities while cultivating a culture of exc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $100K *

Champion client relationships and drive strategic initiatives in the pharmaceutical sector. Leverage expertise in brand strategy and compliance to manage high-impact projects, ensuring seamless collab...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Staffing

$140K - $150K *

Partner with us to deliver compassionate, whole-person care for patients with substance use disorders through our innovative telehealth platform, ensuring effective treatment and support in a fully re...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $201K *

Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$60K - $250K *

Drive impactful connections in healthcare by matching providers with facilities. Leverage your sales expertise to build relationships, negotiate contracts, and contribute to a rewarding mission that e...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $185K *

Explore the frontier of veterinary pharmacology by leading in vivo PK/PD studies across multiple species. Collaborate with multidisciplinary teams to enhance drug candidates from early research throug...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Lead community engagement initiatives to enhance patient advocacy for Becker Muscular Dystrophy. Collaborate with local organizations, educate patients, and build networks to ensure access to quality...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$153K - $203K *

Drive global access and pricing strategies for hematology assets, ensuring timely reimbursement and optimal patient access. Collaborate with cross-functional teams to develop evidence-based toolkits a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $175K *

Champion quality oversight at CMOs, ensuring compliance with cGMPs. Lead QA operations, manage batch records, and address deviations while supporting regulatory filings and audits to maintain high man...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $185K *

Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $196K *

Unlock potential by leading strategic government programs, managing P&L, and driving operational excellence. Oversee contract delivery, mentor staff, and foster client relationships to ensure growth a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $230K *

Drive impactful oncology solutions by building relationships with key stakeholders. Leverage your expertise to exceed performance goals and enhance patient access to innovative therapies while managin...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$268K - $466K *

Champion early clinical development in a dynamic team. Lead clinical research physician role for first-in-human studies, ensuring compliance and collaboration across scientific and regulatory areas to...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a team that's dedicated to enhancing patient access through strategic design and management of support programs. Oversee vendor relationships and ensure compliance while driving initiatives that...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$136K - $187K *

Unlock potential by serving as a vital resource for patients and caregivers, providing education and support for managing generalized Myasthenia Gravis while coordinating treatment and navigating insu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $259K *

Lead the charge in optimizing global drug safety operations, ensuring compliance and excellence in pharmacovigilance. Drive strategic initiatives, manage vendor relationships, and enhance processes to...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$300K - $500K+*

Join a dynamic team as a senior leader driving portfolio performance across the eastern U.S. Oversee regional execution, manage a team of directors, and collaborate on national strategies to enhance b...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.