Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$156K - $211K *

Unlock your potential as a Senior Machine Learning Engineer, driving innovative AI solutions. Collaborate with cross-functional teams to develop scalable prototypes, translating complex business needs...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Champion the legal landscape for Phase 3 and commercial activities in the Americas, providing strategic counsel across the product lifecycle while partnering closely with commercial and medical affair...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$201K - $251K *

Lead strategic forecasting initiatives to drive decision-making in oncology. Collaborate with cross-functional teams to develop long-term models and communicate insights that shape product and portfol...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Collaborate with healthcare providers to drive commercial performance and product adoption. Engage in territory business planning, support product launches, and optimize patient access to innovative t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Lead the charge in enhancing mental health services within a correctional facility. Oversee clinical operations, manage budgets, and ensure compliance while collaborating with multidisciplinary teams...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Join a team that's dedicated to providing high-quality psychotherapy to older adults. Enjoy flexible scheduling, robust support, and opportunities to grow while making a meaningful impact in a collabo...

Alabama, USRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $85K *

Elevate your career by managing the 340B Drug Pricing Program, ensuring compliance and operational excellence for diverse healthcare clients. Collaborate cross-functionally while driving program integ...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $212K *

Transform your career by serving as a scientific liaison, building relationships with key medical experts, and communicating vital information to enhance patient care in the ophthalmology and endocrin...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by mentoring new providers through virtual education, ensuring a seamless onboarding experience. Leverage your clinical expertise to foster growth in both primary care and behavioral...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $160K *

Drive strategic sales initiatives in Long Term Care, fostering relationships with key stakeholders to enhance product access and achieve sales goals while aligning with organizational objectives and v...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$155K - $175K *

Champion the field as a Medical Science Liaison, driving prelaunch strategies and fostering relationships with key stakeholders. Leverage clinical insights to educate and influence healthcare professi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Empower patient care through expert image interpretation and guidance in diagnostic radiology. Collaborate on quality assurance, oversee technical standards, and educate staff while ensuring optimal p...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Unlock a seamless end-user experience by overseeing technical support, mentoring, and cross-functional collaboration in a dynamic IT environment dedicated to operational excellence and service improve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive revenue cycle operations by managing processes from entry to adjudication. Lead teams, implement efficiencies, and ensure compliance while optimizing cash collections and performance metrics for...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Drive innovative palliative care solutions for members with complex needs, providing compassionate, evidence-based support through telehealth. Collaborate with interdisciplinary teams to enhance patie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$156K - $214K *

Inspire growth by leading an Enterprise CPG sales team, driving strategic partnerships with top-tier brands, and influencing C-suite executives to leverage innovative insights for impactful decisions...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Media

$168K - $231K *

Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$152K - $202K *

Drive patient access by leveraging your expertise in reimbursement and market access. Collaborate with healthcare providers to navigate complex payer landscapes, ensuring timely access to therapies wh...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Elevate your career by leading HCP engagement and clinical marketing initiatives. Drive strategic insights and educational content for the HSCT portfolio, fostering impactful connections and enhancing...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion sales growth in the dietary supplements sector by managing client relationships, analyzing market trends, and driving innovative solutions to meet profitability targets and enhance brand posi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$68K - $97K *

Lead operational stability and process standardization for transportation across multiple facilities. Collaborate with planners and logistics partners to enhance delivery performance and resolve disru...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.