Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$94K - $130K *

Shape the future of project management by leading complex initiatives and coordinating cross-functional teams. Drive clarity and accountability while fostering a culture of excellence in a dynamic, en...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $192K *

Drive impactful data solutions by designing ETL pipelines, developing data models, and collaborating with analytics teams to support business objectives through data-driven insights and reporting...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$192K - $226K *

Join a team that drives insights through data science, optimizing mobile marketing efforts and maximizing user engagement. Collaborate cross-functionally while employing advanced analytics and measure...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Shape the future of indirect tax compliance and strategy. Collaborate across finance and with external partners to ensure compliance, mitigate risks, and drive operational success while managing audit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$88K - $154K *

Analyze and enhance compensation strategies, ensuring competitive and compliant practices. Collaborate with HR and management to optimize job descriptions, conduct market analysis, and deliver insight...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$156K - $195K *

Champion the global eDiscovery Technology practice, leading a diverse team to innovate AI-assisted workflows, ensuring defensibility and quality across jurisdictions while driving growth and operation...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$133K - $186K *

Optimize developer engagement by managing the user journey from first touch to activation. Collaborate with teams to enhance the Developer Hub and drive measurable growth through effective lifecycle m...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Transform the Private Equity landscape by leading FP&A initiatives, enhancing operational efficiencies, and mentoring teams to deliver tailored solutions that drive sustainable value creation for clie...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$105K - $141K *

Unlock customer insights to drive strategic decisions across marketing, product, and sales. Lead complex projects, analyze data, and deliver actionable recommendations that enhance customer experience...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$132K - $234K *

Elevate your career by supporting complex software sales cycles through impactful product demonstrations and tailored solutions. Collaborate with clients and partners to drive pipeline conversion and...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$122K - $204K *

Unlock insights as you lead market research initiatives, driving strategic decisions through data storytelling and customer understanding. Collaborate with stakeholders to enhance brand strategies and...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Develop high-quality medical content across multiple therapeutic areas, leading a team of writers while collaborating with clients and stakeholders to ensure strategic alignment and adherence to regul...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's redefining operational excellence by driving product innovation for fleet management. Collaborate across functions to enhance delivery quality, optimize performance, and elevate cus...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$140K - $175K *

Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$101K - $125K *

Unlock your potential by driving growth as a key player in a dynamic sales team. Collaborate with talented professionals to deliver tailored solutions and foster long-term client relationships, ultima...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful technology partnerships to enhance integrations and co-sell solutions. Collaborate with product teams and partners to create joint offerings, ensuring UptimeAI's presence in enterprise...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $135K *

Optimize product delivery in fintech by leading cross-functional teams, translating strategic vision into actionable requirements, and ensuring high-quality outcomes. Drive technical engagement and ma...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$200K - $235K *

Drive product excellence by owning the lifecycle and security of high-performance client SaaS platforms hosted on AWS. Lead a dedicated team to optimize operations, ensure compliance, and deliver seam...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by leading the full sales cycle, building executive relationships, and driving business transformation across industries. Collaborate with teams to innovate sales processes and ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$143K - $169K *

Advance your career by leading a dedicated revenue accounting team, enhancing processes, and ensuring effective implementation of revenue guidance in a fast-paced retail environment. Collaborate cross...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$82K - $112K *

Shape compelling product narratives by leveraging market insights and AI tools. Collaborate cross-functionally to drive go-to-market strategies, ensuring impactful messaging and training materials tha...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $145K *

Lead the charge in developing a robust quality control program, managing a team to enhance operational processes, mitigate risks, and ensure compliance across lending operations while leveraging autom...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Transform regional sales operations by leading high-performing teams, driving growth, and optimizing execution across multiple markets. Foster talent development and ensure operational excellence to a...

1 week ago

  •   5 - 7 years exp.  •   Staffing

$96K - $123K *

Lead the charge in delivering innovative Interfaces and API solutions, enhancing supply chain and clinical workflows. Collaborate cross-functionally to define product requirements and drive adoption...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive go-to-market strategy for AI-powered healthcare solutions, collaborating cross-functionally to enhance product positioning, messaging, and performance. Own marketing execution and leverage insig...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.