Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$140K - $195K *

Pioneer AI-driven solutions in capital markets and legal disclosure. Lead product strategy and execution for a cloud-based platform, collaborating with cross-functional teams to deliver innovative, tr...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K - $280K *

Champion strategic growth by leading a high-performing sales team focused on K-12 core curriculum and supplemental products. Drive revenue, build talent, and foster partnerships with education leaders...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Shape the future of talent acquisition by managing end-to-end recruitment processes, collaborating with cross-functional teams, and optimizing hiring strategies to attract top talent in a fast-paced e...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Transportation

$178K - $338K *

Inspire innovation in healthcare by architecting RPA solutions that streamline revenue cycle processes while providing project management and technical expertise to drive client success and team colla...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$190K - $210K *

Transform the contract management landscape for large-scale data center projects. Oversee RFx processes, negotiate contracts, and ensure compliance while collaborating with cross-functional teams to m...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Champion the delivery of large-scale data center projects, overseeing field operations, client coordination, and compliance across multiple sites. Drive project success through effective management of...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$120K - $145K *

Accelerate commercial growth by defining strategies for product families, collaborating across teams to translate market insights into actionable plans that drive revenue, profitability, and customer...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $120K *

Elevate talent management by executing core programs, enhancing employee experience, and driving performance initiatives. Lead cross-functional projects, ensuring accountability and operational contin...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$174K - $234K *

Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing Sales Development teams to enhance pipeline quality and revenue growth. Collaborate with cross-functional partners to align strategies and drive performance through effec...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$89K - $120K *

Drive impactful payment product initiatives, delivering outcomes through strategic execution and collaboration in a fast-paced fintech environment. Leverage expertise in healthcare payments to enhance...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K *

Manage the strategic roadmap for TikTok Shop clients, driving growth through data-driven decisions and hands-on execution. Collaborate with teams to optimize product listings and performance while lea...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by building and deploying AI systems across diverse businesses. Collaborate with CEOs to identify needs, create prototypes, and drive growth through innovative solutions while managin...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $159K *

Analyze and build evaluation frameworks for AI agents, ensuring quality and performance meet client and business standards. Collaborate with cross-functional teams to establish testing methodologies a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $164K *

Lead our cybersecurity and governance initiatives, enhancing security operations and risk management while driving compliance with CMMC 2.0 and ISO/IEC 27001 standards. Collaborate across teams to imp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$225K - $265K *

Partner with us to lead a high-performing engineering team, driving innovation and efficiency in our travel marketplace. You'll manage project lifecycles, enhance collaboration, and champion a custome...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$148K - $175K *

Join us to drive product strategy and execution for FP&A workflows, enhancing planning, reporting, and automation. Collaborate across Finance and Engineering to improve systems and user experiences, e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$189K - $222K *

Champion client success by leading post-sale operations, ensuring seamless onboarding, delivery, and retention. Drive growth through strategic account management and operational excellence while foste...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$265K - $295K *

Shape community engagement strategies to foster trust and collaboration with local stakeholders, ensuring Anthropic's infrastructure projects benefit the communities we serve while navigating complex...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive Agile transformation by leading complex projects, managing dependencies, and fostering collaboration across teams. Empower stakeholders through effective communication and continuous improvement...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the strategy for the Commitments product, enhancing customer compliance tracking through AI. Collaborate with cross-functional teams to drive adoption and deliver impactful solutions that address...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$94K - $293K *

Shape the future of finance in Life Sciences by partnering with executives to drive efficiency, profitability, and innovation through advanced processes and technologies. Leverage your expertise to tr...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Lead the charge in driving revenue growth by managing the full sales cycle for innovative event marketing solutions. Utilize your entrepreneurial spirit and consultative approach to transform client o...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$117K - $209K *

Own and optimize the end-to-end Procure-to-Pay function, ensuring seamless operations across Procurement, Accounts Payable, and supplier management while driving governance, performance, and stakehold...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.