Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$100K - $120K *

Lead the strategic implementation of marketing technology solutions, optimizing platforms and data systems to enhance constituent engagement and drive data-informed decision-making across the organiza...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Engage in comprehensive cost planning and commercial management for diverse projects, leveraging contractor-side expertise to deliver evidence-based advice and robust cost positions throughout the pro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Shape the future of client strategy by leading growth initiatives, managing relationships, and driving performance metrics. Collaborate across teams to enhance brand success and ensure seamless execut...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$120K - $193K *

Join a team that's redefining security product management by leading the strategy and delivery of innovative security solutions. Drive efficiency and compliance while enhancing developer experiences t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$94K - $293K *

Drive data engineering initiatives by creating scalable data solutions for ingestion, transformation, and governance. Leverage cloud technologies and best practices to optimize data pipelines and ensu...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Pioneer global payroll operations, ensuring compliance and accuracy across multiple regions. Lead payroll processes and provide exceptional support as you contribute to the team’s expansion and effici...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$67K - $199K *

Elevate product strategy and execution for Epic EHR solutions, driving user-centric design and agile methodologies. Collaborate with stakeholders to enhance healthcare delivery through innovative info...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive the evolution of a cutting-edge CI/CD platform, integrating AI tools and leading a team of DevOps engineers. Own production releases and implement modern delivery practices to enhance software d...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $176K *

Unlock potential by driving strategic growth initiatives through competitive intelligence and market insights. Collaborate with cross-functional teams to enhance sales effectiveness and client retenti...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$149K - $234K *

Transform education by driving product strategy and execution, collaborating with cross-functional teams to enhance user experiences for learners, families, and educators. Shape impactful solutions th...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$188K - $282K *

Engage with leading academic partners to drive ultrasound innovation, fostering collaboration between research and product development to enhance technology and clinical applications in healthcare...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$145K - $190K *

Unlock your potential by leading transformative Oracle Cloud Procurement initiatives in healthcare. Engage with clients, mentor teams, and drive impactful solutions while enhancing operational efficie...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$141K - $166K *

Lead the charge in shaping product messaging and go-to-market strategies, driving awareness and adoption through cross-functional collaboration and strategic insights. This role demands a proactive in...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion operational excellence by leading training support for mission readiness. Oversee all aspects of training management, personnel coordination, and mission execution within a dynamic environmen...

4 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$124K - $280K *

Lead the charge in large-scale Oracle program management, coordinating projects and stakeholders to ensure successful delivery of Oracle solutions while driving operational excellence and aligning wit...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $130K *

Drive commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and decision-making. Lead cross-functional teams...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate data-driven decision-making by analyzing clinician networks to optimize patient care. Collaborate with cross-functional teams to enhance operational efficiency and improve healthcare outcomes...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Champion impactful programs by leading cross-functional teams, driving strategic alignment, and ensuring seamless execution. Leverage your expertise to manage complex initiatives that delight customer...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $160K *

Drive customer success by optimizing digital journeys and automating solutions. Collaborate cross-functionally to enhance user experiences while leveraging AI and coding skills to maintain and deploy...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$243K - $251K *

Join a team that's dedicated to enhancing internal audit processes through innovative risk management strategies, leveraging data analytics and technology to drive efficiency and compliance across the...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$140K - $160K *

Lead strategic life sciences accounts, driving growth and team development while ensuring project success and client satisfaction through strong relationships and innovative solutions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Unlock potential by leading global integrated campaigns that drive pipeline and revenue. As a player-coach, you'll manage a high-performing team while executing multi-channel strategies that align wit...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$125K - $170K *

Champion pricing strategies for complex public-sector contracts, leading cost model development and commercial analysis. Collaborate with cross-functional teams to ensure compliance and competitivenes...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Transportation

$101K - $165K *

Develop and execute integrated marketing programs to drive merchant acquisition and activation through platforms and ISVs, leveraging data to optimize performance and enhance partner relationships for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.