Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$175K - $185K *

Shape the future of product marketing by crafting compelling narratives and strategies. Collaborate with cross-functional teams to translate technical capabilities into impactful content and drive suc...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$93K - $166K *

Transform the future by leading complex projects that drive innovation and efficiency. Collaborate with cross-functional teams to deliver business value while managing scope, schedule, and resources i...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$138K - $165K *

Lead the charge in driving complex integration programs that connect products and platforms at scale. Collaborate across teams to ensure seamless interoperability and operational excellence, shaping t...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Transform global partner marketing strategies to drive growth and engagement. Collaborate with cross-functional teams to execute integrated campaigns and optimize performance across diverse markets, e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $130K *

Drive customer success by leading a team of managers to enhance client experiences, ensuring value delivery and operational excellence in multifamily property management. Collaborate cross-functionall...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $100K *

Join a team that's driving impactful client strategies in digital marketing. As a Supervisor, you'll lead a dynamic team, manage client relationships, and oversee integrated campaigns across omnichann...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $165K *

Join a team that's redefining healthcare technology by owning the product roadmap, translating company goals into actionable tasks, and ensuring seamless delivery of AI-driven solutions that enhance p...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$120K - $135K *

Empower our analytics team by managing complex datasets and driving data-driven decisions across multiple stakeholders. Your expertise will enhance operational efficiency and ensure timely project del...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive operational excellence as you manage tech stacks and workflows, delivering data-driven insights and aligning cross-functional teams for revenue growth and partner success...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $105K *

Elevate your career by managing the operational lifecycle of B2G products. Drive onboarding, renewals, and readiness activities while ensuring smooth day-to-day operations. Collaborate cross-functiona...

Iowa City, IARemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $135K *

Lead the charge in driving strategic project delivery across multiple squads, ensuring alignment with business priorities and effective communication among stakeholders. Utilize program management exp...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$63K - $98K *

Lead the charge in ensuring seamless onboarding for new customers, coordinating efforts across teams to deliver a professional transition from sales to support, while fostering strong relationships an...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $261K *

Shape the future of product marketing by driving growth through strategic enablement, cross-functional collaboration, and compelling storytelling that connects technical solutions to customer needs in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$123K - $207K *

Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $200K *

Elevate your career by leading HCP engagement and clinical marketing initiatives. Drive strategic insights and educational content for the HSCT portfolio, fostering impactful connections and enhancing...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$275K - $325K *

Drive the venture and private equity business by owning strategy, partnerships, and P&L. Collaborate with teams to establish Flex as the primary financial institution in the sector, leveraging your ex...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$73K - $182K *

Transform the future of AI learning by developing engaging, hands-on technical content that empowers adult learners to master machine learning and AI applications, ensuring instructional quality and t...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$73K - $182K *

Create impactful AI learning experiences by developing courses, labs, and assessments. Collaborate with experts to ensure technical accuracy and instructional quality, enabling learners to apply AI sk...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$82K - $108K *

Grow your career with a dynamic role driving strategic growth in wholesale and government sales. Lead account management, cultivate partnerships, and enhance market presence while collaborating cross...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Optimize program management across the Customer Experience organization, ensuring strategic alignment and operational excellence. Lead cross-functional teams, establish governance frameworks, and driv...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$155K - $194K *

Join us to lead impactful HCP marketing execution, driving adoption and engagement through strategic field initiatives. Collaborate cross-functionally to optimize resources and enhance customer experi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Join a dynamic team to lead multiple client engagements, driving innovative solutions and strategic direction. Foster cross-functional collaboration in a fast-paced environment with a focus on deliver...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower partner marketing initiatives by developing strategies that drive qualified referrals and pipeline growth across diverse partner ecosystems in North America and EMEA. Collaborate with stakehol...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Staffing

$94K - $117K *

Champion integrated demand generation initiatives to drive pipeline and revenue growth. Leverage advanced digital marketing expertise and collaborate with cross-functional teams to optimize multi-chan...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$99K - $232K *

Join a team that's empowering clients to optimize operational efficiency through SAP consulting. Lead projects, mentor teams, and drive innovation while ensuring seamless integration of business appli...

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.