Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $140K *

Elevate financial integrity by leading month-end and year-end closes, ensuring compliance with US GAAP. Collaborate across teams to enhance reporting accuracy and streamline processes, driving operati...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $120K *

Join a dynamic team as you oversee IT operations, user lifecycle management, and security for a growing organization. This hands-on role allows you to set standards and processes while serving as the...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion revenue growth by managing ISV channel partners, driving strategies, and optimizing performance. Build strong relationships, analyze data, and identify new opportunities to enhance profitabil...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead complex, cross-functional marketing initiatives from planning to execution, driving accountability and collaboration across teams while enhancing project management processes and methodologies fo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by driving enterprise sales through consultative approaches, managing complex deals with multiple stakeholders, and leveraging a proven sales methodology to achieve targets and foster...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$192K - $266K *

Drive best-in-class travel support through strategic leadership and operational excellence. Oversee lodging, flights, and customer advocacy, fostering a culture of continuous improvement and exception...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$160K - $200K *

Drive growth and innovation by leading commercial strategies in the Media, Entertainment, and Gaming sectors. Collaborate with teams to enhance client relationships, identify new opportunities, and en...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Media

$229K - $267K *

Innovate the consumer digital experience by leading a cross-functional team to enhance our website, mobile app, and web portal. Define a multi-year vision, prioritize initiatives, and drive engagement...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$94K - $266K *

Join us to lead innovative cloud-based contact center projects, driving success for Mid-Market & Enterprise clients. Utilize your project management expertise to deliver cutting-edge solutions and fos...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $210K *

Transform global payroll operations by leading a team to ensure compliance, accuracy, and efficiency across US and international payrolls while managing complex tax and pay issues...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$79K - $99K *

Elevate your career by executing and advancing a dynamic organic social strategy. Collaborate with cross-functional teams to create engaging content that resonates with audiences and drives brand rele...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$130K - $140K *

Transform customer relationships and drive growth by identifying upsell opportunities and ensuring satisfaction within our Health and Wellness vertical. Collaborate with teams to advocate for clients...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $90K *

Tackle the challenge of crafting compelling direct-response copy across multiple platforms, driving engagement and conversions for a high-impact men's coaching company. Collaborate closely with market...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$153K - $213K *

Take ownership of a customer-facing product area, driving strategy and execution. Collaborate cross-functionally to enhance user experience, leverage AI, and achieve key performance metrics while deli...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $120K *

Join a dynamic team to drive customer activation and retention strategies across the prescription lifecycle. Collaborate cross-functionally to optimize customer journeys and deliver measurable growth...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$183K - $215K *

Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Join our lifecycle team to drive innovative marketing campaigns for our product portfolio. You'll shape strategies, analyze performance, and enhance user engagement, all while collaborating across dep...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$95K - $115K *

Drive operational excellence by managing multiple service sites, enhancing safety, and fostering team development while ensuring high customer satisfaction and efficient budget management across a des...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $189K *

Join a team that's redefining oncology engagement through innovative social media strategies. As a key player, you'll manage social execution across diverse tumor types, enhancing connections with hea...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Lead the charge in managing key client relationships within Pharmacy Benefit Management, ensuring high-quality service delivery and client satisfaction through effective communication and consultative...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $271K *

Unlock potential by leading pre-sales efforts for complex software solutions. Collaborate with clients and partners to deliver tailored demonstrations, support RFPs, and develop reusable assets that d...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$130K - $170K *

Champion global payroll operations by managing processes, team leadership, and compliance initiatives across multiple regions, driving strategic improvements to enhance efficiency and accuracy while e...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Staffing

$135K - $159K *

Optimize client partnerships by driving strategic outreach and proposals. Leverage AI tools to enhance sales cycles, mentor peers, and contribute to revenue growth through long-term relationships and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $100K *

Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.