Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Lead the charge in employee benefits by mentoring a sales team, driving growth, and fostering broker relationships. Utilize your expertise to educate clients and brokers on innovative solutions while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$171K - $269K *

Lead the charge in defining and evolving data architecture and engineering standards for scalable, secure enterprise data platforms. Collaborate across teams to deliver reliable, actionable data produ...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$63K - $177K *

Join a team that's transforming the insurance brokerage landscape by analyzing business challenges, designing innovative solutions, and delivering impactful results through collaboration and advanced...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$228K - $285K *

Pioneer advancements in AI inference platforms, driving strategy and execution across cross-functional teams to enhance scalability and reliability for enterprise customers. Lead product initiatives f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$85K - $98K *

Lead the charge in high-volume talent acquisition, overseeing a dynamic team to enhance recruiting strategies, optimize processes, and ensure exceptional candidate experiences while achieving hiring g...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in optimizing top-of-funnel marketing operations, driving measurable pipeline growth through strategic planning, data governance, and team leadership. Collaborate with cross-functional...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$124K - $169K *

Optimize cross-portfolio analytics to enhance Gross-to-Net performance, identify anomalies, and drive process improvements. Collaborate with diverse teams to deliver actionable insights and scalable r...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$232K - $325K *

Empower innovation by serving as a leading expert in relevance evaluation. Collaborate to enhance ranking and recommendation systems, driving product strategy through rigorous analysis and shaping the...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Media

$160K - $200K *

Unlock potential by leading a dynamic marketing team to drive E-commerce growth. Collaborate on strategy, optimize performance, and ensure creative alignment while fostering a high-impact work environ...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Innovate your career by leading the strategy and creation of impactful B2B content across various formats. Collaborate with teams to enhance engagement and drive demand through high-quality, optimized...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Join a dynamic team as you drive client success through deep product expertise, fostering relationships that enhance adoption and deliver measurable business value across multi-site manufacturing orga...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Unlock growth by leading federal capture efforts, developing strategies, and securing contracts. Collaborate with cross-functional teams to align customer needs with capabilities, ensuring compliance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$143K - $199K *

Strategize and optimize marketing technology architecture and integrations. Drive platform health and feature development while collaborating with cross-functional teams to build robust solutions that...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $140K *

Champion the evolution of a high-traffic website by leading strategy, governance, and performance optimization. Drive a seamless migration to Webflow while enhancing user experience and engagement thr...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$79K - $98K *

Join us to lead product management for our Medicare Part D program, ensuring compliance with CMS regulations while enhancing processes and client satisfaction. Your expertise will drive operational ex...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$148K - $185K *

Drive product strategy and innovation to enhance vertical partnerships, focusing on tailored experiences across industries. Collaborate cross-functionally to deliver impactful solutions that boost use...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Media

$100K - $140K *

Champion product strategy and innovation, driving enhancements through AI and user insights. Collaborate with teams to deliver measurable outcomes and improve workflows in high-stakes assessment envir...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $170K *

Contribute to performance optimization by diagnosing shifts in a $30B portfolio. Leverage data insights to drive strategic recommendations, enhance client outcomes, and collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K *

Take ownership of cybersecurity compliance initiatives, leading risk management and strategic advisory services to enhance client security programs and ensure adherence to regulatory standards across...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Drive the successful execution of multiple e-discovery projects, collaborating with legal teams and mentoring junior staff. Ensure quality standards, manage budgets, and maintain client relationships...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$132K - $189K *

Empower teams to execute site-specific strategies, ensuring seamless project delivery and milestone tracking throughout the data center lifecycle while collaborating with cross-functional partners...

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Lead and enhance our 24x7 security operations team, driving effective incident response and operational excellence across diverse customer environments while fostering talent and improving detection c...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Unlock potential by driving customer success through strategic guidance, technical solutions, and AI optimization. Collaborate with teams to enhance product adoption and retention, ensuring measurable...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.