Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Oncologist Jobs in Oklahoma

Sort By: Relevance

$136K - $181K *

Take ownership of CRA management by leading teams, developing metrics, and ensuring compliance with monitoring standards. Drive continuous improvement and optimize effectiveness across the Site Manage...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $97K *

Contribute to program success by supporting planning, execution, and management of projects. Analyze data, prepare reports, and optimize resources to ensure objectives are met within scope, time, and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$204K - $274K *

Champion the U.S. Biologics Regulatory CMC team by providing strategic leadership, ensuring timely regulatory submissions, and fostering collaboration among global stakeholders to drive innovative bio...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$157K - $256K *

Shape strategic pricing and channel strategies for innovative therapies, ensuring patient access and affordability. Lead cross-functional initiatives, optimize distribution models, and drive market in...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$119K - $145K *

Advance supply chain efficiency by optimizing operations, collaborating cross-functionally, and implementing innovative solutions. Engage with stakeholders to analyze performance metrics and support k...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$176K - $287K *

Lead the charge in advancing scientific discourse by engaging KOLs and HCPs in Hematological Malignancies. Drive strategic medical initiatives while fostering relationships to enhance research and cli...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $185K *

Explore the frontier of veterinary pharmacology by leading in vivo PK/PD studies across multiple species. Collaborate with multidisciplinary teams to enhance drug candidates from early research throug...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$155K - $160K *

Shape the future of data solutions by designing scalable architectures that drive AI and analytics initiatives. Collaborate with cross-functional teams to implement innovative strategies that enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $190K *

Advance your career by shaping analyst relations and market perception in AI and automation. Collaborate with cross-functional teams to drive impactful evaluations and strategic narratives that enhanc...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $151K *

Champion operational excellence by ensuring radiation safety and EHS compliance across cyclotron manufacturing and PET nuclear pharmacy facilities in the South Central US, while collaborating with cro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$212K - $270K *

Drive growth and strategy as a Senior Director, leading a high-performing sales team to achieve exceptional results in a dynamic, fast-paced environment focused on new business and expansion across di...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Consumer Technology

$117K - $189K *

Join a team that's shaping the future of pharmaceutical quality by leading compliance initiatives and building a robust Quality Management System to support innovative therapies in a dynamic, collabor...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Innovate by leading the architectural transformation of a legacy platform into a scalable, AI-driven solution. Your expertise will guide modernization efforts while enhancing performance and security...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Join a team that's dedicated to delivering exceptional financial services. This role involves managing accounts payable, payroll, cash management, and month-end reconciliations while collaborating clo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$121K - $132K *

Engage as a key technical leader in enterprise AI/ML architecture, collaborating with clients to design scalable solutions. Drive AI development and deployment, ensuring alignment with business needs...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$155K - $192K *

Lead the charge in transforming member acquisition strategies through data-driven insights, optimizing marketing performance, and driving sustainable growth in a fully remote environment. Collaborate...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Drive technical excellence by designing systems, setting standards, and mentoring engineers without formal management. Collaborate with Product to ensure alignment and tackle engineering challenges ac...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $205K *

Take ownership of driving sales strategy and revenue growth for a new kidney transplant product. Collaborate cross-functionally, build key relationships, and develop strategic account plans to ensure...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$232K - $290K *

Shape the future of global People Operations by leading innovative HR service delivery, enhancing employee experiences, and driving operational excellence in a rapidly scaling biopharmaceutical enviro...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$147K - $251K *

Unlock potential by driving revenue growth within U.S. Federal Government accounts. Engage stakeholders, execute account strategies, and ensure customer satisfaction through adoption and retention of...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $100K *

Accelerate progress at workforce development by managing training programs and initiatives that enhance public health laboratory capabilities. Collaborate with partners to design, implement, and evalu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Shape the future of technical content by building a robust function from the ground up, focusing on client engagement and leveraging emerging technologies to enhance understanding and communication...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$225K - $250K *

Champion compliance and innovation as you navigate complex legal landscapes, supporting diverse teams in a fast-paced environment. Leverage your expertise to drive growth while managing legal risks ac...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$225K - $281K *

Shape the future of application security by leading strategy and initiatives across teams. Drive secure design and standards, mentor engineers, and tackle complex security challenges in a collaborativ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.