Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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1,000+

Oncologist Jobs in Oklahoma

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$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to delivering exceptional outpatient care while leading a dynamic clinic. This role combines hands-on patient treatment with strategic leadership to enhance clinic perform...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower a thriving outpatient clinic by leading a dedicated team, enhancing patient care, and driving operational success while maintaining a hands-on approach to physical therapy...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Champion strategic growth by managing major law enforcement accounts, driving revenue, and fostering relationships with key stakeholders. Collaborate cross-functionally to ensure successful outcomes a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$156K - $214K *

Transform the digital landscape for Medical Affairs by owning product vision, prioritizing backlogs, and ensuring compliance. Collaborate with experts to deliver insights and enhance engagement throug...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$245K - $265K *

Build impactful partnerships with Medical Experts to enhance neurology care. Drive strategic insights and collaboration across teams, influencing marketing and education initiatives while engaging wit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's shaping global regulatory strategy for rare disease therapies. In this pivotal role, you'll lead submissions and agency interactions across the US, EU, UK, and Japan, driving execut...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Staffing

$100K - $160K *

Join a team that's transforming healthcare with AI solutions. As an AI Solutions Engineer, you'll develop integrations and tools that enhance customer workflows, bridging the gap between clients and o...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive transformative AI initiatives across departments by leading a strategic team in designing scalable, agentic workflows that enhance decision-making and efficiency, ensuring measurable business ou...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $150K *

Shape the future of safety in a dynamic environment by developing and enhancing EHS programs. Collaborate across teams to foster a culture of safety and compliance, ensuring adherence to regulations w...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$105K - $129K *

Drive impactful market analysis and reporting as a Senior Analyst, leveraging data to guide strategic investments and growth opportunities. Collaborate with teams to enhance decision-making and optimi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$184K - $253K *

Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $170K *

Design innovative AI solutions on Microsoft Azure, bridging business needs and engineering execution. Own the architecture, ensure security, and lead the build process while adapting to evolving proje...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's leading Medicaid programs and initiatives, driving operational excellence and policy implementation while managing multidisciplinary teams and enhancing organizational performance a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's redefining healthcare recruiting by building and scaling a high-impact Direct Employer business through innovative sales strategies and cutting-edge technology, driving growth direc...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Staffing

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Elevate healthcare interoperability by designing and supporting MEDITECH interfaces. Collaborate with teams to enhance data exchange, improve patient care, and ensure seamless integration across syste...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$220K - $270K *

Join a team that's shaping the future of renewable energy finance by managing complex transactions and driving innovative legal solutions. Collaborate cross-functionally to optimize processes and enha...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $180K *

Champion innovation by developing full-stack web applications using TypeScript. Collaborate in a dynamic, remote-first team to deliver engaging user experiences, streamline operations, and lead techni...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Shape the future of brand strategy by leading integrated initiatives, translating insights into actionable plans, and collaborating with cross-functional teams to deliver impactful solutions across as...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $148K *

Drive your career with impactful consulting in healthcare, enhancing operational efficiency and financial performance for provider organizations through data analysis and project management...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.