Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

Sort By: Relevance

$110K - $130K *

Champion the clinical supply chain for late-stage oncology trials, ensuring seamless operations and communication between sites, suppliers, and stakeholders. Drive continuous improvement and complianc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $153K *

Transform financial management practices by leading budgeting, forecasting, and resource allocation efforts. Collaborate with teams to enhance decision-making and optimize financial systems, ensuring...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Drive strategic growth by managing key Pharma and Biotech accounts, engaging C-suite executives, and leading expansion sales processes. Collaborate cross-functionally to enhance client experiences and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $210K *

Shape the future of financial reporting by leading SEC compliance and technical accounting. Drive policy development, optimize processes, and collaborate with cross-functional teams to support growth...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$83K - $113K *

Drive regional clinical study delivery by supporting management and execution of trials, ensuring quality standards and timelines are met. Collaborate with stakeholders and contribute to operational e...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$158K - $250K *

Join a team that's redefining market access strategies in the pharma industry. Leverage your expertise in managed care and payer relationships to drive coverage and reimbursement for innovative therap...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$119K - $179K *

Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Transform the future of business applications by leading strategy, delivery, and operations. Collaborate with multidisciplinary teams to enhance core processes and drive value through effective system...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Champion the full sales cycle for top enterprise accounts, utilizing a consultative approach to solve complex challenges. Drive impactful relationships with stakeholders, and navigate lengthy processe...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Shape the future of tax strategies by leading our diverse team and managing client relationships. Engage with various industries to deliver tailored solutions and ensure client satisfaction while driv...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Drive your career by leading regional strategy and performance in the Middle Market Nonprofit sector. Shape client relationships and foster a high-performing team to deliver integrated banking solutio...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $130K *

Grow your career with a dynamic role that involves conducting in-depth research across various topics, delivering actionable insights, and collaborating with a high-performing team to tackle complex q...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Transform healthcare engagement by building relationships with HCPs through digital interactions and telephone conversations, promoting products, and achieving sales goals while ensuring compliance wi...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform inpatient coding operations by leading a dedicated team to ensure accurate coding, compliance, and timely billing. Collaborate with clinical and administrative staff to enhance financial per...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a team that's transforming women's health by driving sales in OB/GYN and maternal-fetal medicine. You'll manage the full sales cycle, leveraging existing relationships to expand our reach and ens...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $164K *

Unlock potential by leading research and analysis to identify system impacts, dependencies, and business needs. Collaborate with stakeholders to enhance processes and deliver clear requirements in a d...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform lender relationships by managing program performance, onboarding, and communication. Collaborate with leadership to identify trends and opportunities, ensuring clarity and efficiency in fina...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Drive analytics initiatives that connect Paid Media performance to full-funnel outcomes. Collaborate with cross-functional teams to design measurement frameworks, optimize data models, and provide act...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's transforming software sales by driving technical solutions and creative outreach. Lead the full sales cycle and collaborate cross-functionally to deliver unique insights and busines...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$76K - $93K *

Accelerate progress at customer success by building strong relationships, driving product adoption, and ensuring customer satisfaction. Collaborate cross-functionally to resolve issues and enhance cus...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Join a team that's redefining SaaS sales in the academic sector. Leverage your expertise to innovate AI-driven solutions, build relationships, and drive growth. Collaborate across teams to enhance cli...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of pricing strategy by leading deal governance and commercial frameworks. Collaborate across teams to enhance pricing effectiveness and support ARR growth while guiding complex deal s...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Lead the charge in managing workplace design and construction projects, ensuring operational readiness and accountability across multiple sites while optimizing budgets and vendor performance for succ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$119K - $155K *

Shape the future of enterprise sales by driving growth and cultivating long-term relationships. Manage complex sales cycles and leverage AI tools to optimize efficiency and insights, ensuring customer...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $205K *

Transform sales strategies by driving key account growth, building relationships, and executing plans for a new kidney transplant product. Collaborate cross-functionally to ensure optimal market acces...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.