Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$80K - $95K *

Transform your career by leading operational excellence in a multi-practice medical environment. Drive improvements in efficiency, manage teams, and ensure the highest standards in patient care while...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$205K - $380K *

Drive transformative supply chain initiatives, providing strategic leadership and operational oversight to enhance efficiency and best practices across client hospitals. Collaborate with C-suite execu...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$140K - $170K *

Shape the future of healthcare market strategies by analyzing trends, defining growth initiatives, and collaborating cross-functionally to drive innovation in life science and medical services. Lead m...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$185K - $220K *

Join a team that's redefining engineering service delivery for legal and professional clients. Lead a dynamic organization focused on operational excellence, client satisfaction, and continuous improv...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$135K - $160K *

Champion innovative solutions by advising top financial institutions on identity verification and fraud prevention. Collaborate cross-functionally to ensure seamless client experiences and drive produ...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Advance your career by leading incident response efforts in a dynamic IT environment. Coordinate multi-team activities to restore operations efficiently, ensuring compliance with best practices and dr...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K *

Take ownership of complex mortgage loan evaluations, ensuring compliance with guidelines while assessing borrower risk. Collaborate with internal teams and vendors to facilitate loan approvals and mai...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$74K - $129K *

Elevate healthcare delivery by managing operations for a nationwide virtual medical team. Collaborate with leaders to optimize patient care, drive performance improvements, and implement innovative wo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Support clients in maximizing their Workday investment by implementing and enhancing Adaptive Planning solutions. Drive project success through relationship building, best practices, and exceptional s...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Advance your career by driving market intelligence and product strategy for RUO oncology and transplant products. Collaborate with cross-functional teams to enhance customer relationships and ensure s...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Elevate financial management and strategic planning efforts by providing expert analysis, guidance, and support for budget formulation and execution within a dynamic team focused on mission delivery f...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Drive customer engagement and satisfaction by managing the full customer lifecycle, utilizing innovative AI workflows, and collaborating across teams to enhance service delivery and trust in our solut...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower our analyst relations program by managing evaluations, timelines, and coordination. Collaborate with stakeholders to ensure accurate, timely engagement and support market insights for strategi...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

The Data Integration Specialist at Timely will ensure seamless integration of data between school district systems and Timely's scheduling technology. This role involves collaborating with various sta...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to advancing NMR technology and research. Oversee facility operations, manage user access, and provide expert support to a diverse group of researchers while ensuring safe...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $129K *

Transform healthcare analytics by leveraging your expertise in data analysis, database management, and visualization tools. Collaborate with teams to optimize workflows and deliver impactful solutions...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $179K *

Lead the charge in bridging genomic variants with clinical insights, collaborating with scientists to automate and scale curation workflows. Drive innovation in AI/ML applications while ensuring softw...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $130K *

Join a team that's redefining clinical engagement by leading strategic initiatives to enhance clinician pipelines, improve hiring processes, and foster partnerships across multiple regions, driving or...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$155K - $200K *

Elevate product management by driving vision, strategy, and execution across digital solutions in clinical development. Collaborate with cross-functional teams to enhance user experience and operation...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Join a team that's shaping high-impact strategies and narratives for enterprise growth. Collaborate with senior leaders to craft compelling pitches and support organic initiatives, driving success acr...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Join us to lead nursing practice across ambulatory and inpatient areas, enhancing patient care through education, consultation, and research. Collaborate with clinical leaders to improve orthopedic ca...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$92K - $167K *

Drive strategic initiatives in Medicare Advantage provider networks, analyzing data and collaborating with leadership to enhance performance and achieve goals. Lead complex projects from inception to...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $95K *

Lead the charge in client engagement and lifecycle management, driving retention and organic growth within legal accounts. Build relationships, identify cross-sell opportunities, and ensure high clien...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $92K *

Unlock insights as you support senior analysts in corporate bond and bank loan research. Collaborate on financial models, enhance credit processes, and develop your analytical skills in a dynamic inve...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.