Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$125K - $155K *

Join a team that's driving sales success in the Iowa territory by leveraging your expertise in pharmaceutical products and building strong relationships with healthcare providers to enhance patient ca...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $155K *

Drive sales success by leveraging product knowledge and strong communication skills to engage healthcare providers in the Iowa territory. Utilize analytical abilities for effective territory managemen...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $125K *

Shape the future of pharmacy operations by optimizing customer engagement and operational performance across a national portfolio. Drive proactive interventions and enhance workflow efficiency to ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $113K *

Transform proposal management by leading cross-functional teams to deliver high-quality, compliant responses. Drive efficiency through strategic planning, risk management, and collaboration, ensuring...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$290K - $350K *

Pioneer sales innovation by targeting major enterprises for GRC solutions. You’ll drive revenue growth through cold prospecting, strategic planning, and customer engagement, making a significant impac...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$68K - $116K *

Join a dynamic team to lead clinic operations, enhance patient care, and foster employee development. Drive quality outcomes while utilizing innovative AI technology to streamline documentation and im...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $169K *

Lead product quality initiatives to ensure compliance and continuous improvement throughout the product lifecycle, partnering with cross-functional teams to enhance manufacturing performance and suppo...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Manage a portfolio of strategic enterprise clients, fostering executive relationships and driving retention and adoption. Utilize data and AI tools to enhance client value, mentor team members, and sh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$275K - $350K *

Lead the charge in transforming operations by integrating AI and technology to enhance member and clinician experiences, ensuring efficient care delivery and operational excellence across a distribute...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $143K *

Deliver impactful reporting solutions by translating measurement needs into actionable requirements, managing backlogs, and collaborating with cross-functional teams to ensure effective execution and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$197K - $232K *

Lead growth in a dynamic sales team focused on enterprise accounts, driving execution and collaboration to enhance market reach and customer relationships. Shape strategy and sales processes while bui...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Information Technology

$143K - $193K *

Accelerate progress at the forefront of data-driven transformation in life sciences. Collaborate with leadership to shape and execute enterprise data architecture initiatives, ensuring scalable, trust...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$83K - $222K *

Innovate your career with a Senior Epic Analyst role focused on designing and optimizing Epic solutions for population health and care coordination, while mentoring junior analysts and collaborating w...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$163K - $220K *

Transform vendor strategies and cost management across the organization. Drive financial performance with analytics, lead sourcing events, and collaborate with cross-functional teams to optimize value...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform credentialing operations by leading a dedicated team to ensure compliance, enhance efficiency, and support provider network growth through strategic oversight and process improvement initiat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Collaborate with cross-functional teams to implement and configure innovative solutions on a risk and compliance platform, ensuring customer success through expertise and effective communication in a...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $173K *

Champion a transformative clinical team, leading 60-70 RNs in delivering exceptional post-discharge care. Drive innovative strategies to enhance patient outcomes and foster a culture of collaboration...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in project management excellence, coordinating cross-functional teams to deliver high-quality projects on time and within budget while fostering stakeholder engagement and team develop...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$199K - $370K *

Engage with high-value government accounts nationwide, driving sales of industry-leading cloud solutions. Leverage your expertise in government procurement to build relationships, exceed quotas, and c...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$72K - $116K *

Engage in financial analysis and reporting, developing forecasts and insights. Collaborate across departments to enhance business outcomes and present findings to management, driving strategic decisio...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$91K - $137K *

Shape the future of clinical research by managing site operations, ensuring patient safety, and maintaining data integrity. Collaborate with study teams to oversee monitoring activities and drive succ...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$91K - $137K *

Empower your career by managing clinical research sites, ensuring patient safety, and maintaining data integrity. Collaborate with teams to oversee study implementation and monitoring, while enhancing...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $180K *

Empower clients by owning technical relationships for the Enterprise Suite, guiding them from discovery to implementation. Collaborate with teams to enhance adoption and resolve issues, ensuring seaml...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Contribute to the success of multiple clinical research sites by leading operations, ensuring compliance with regulations, and fostering team development to enhance patient care and operational excell...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.