Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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1,000+

Oncologist Jobs in Iowa

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$125K - $157K *

Join our dynamic team to design and enhance a web portal application, improving user experience and functionality. Collaborate with engineers and product managers to deliver impactful solutions that s...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$61K - $104K *

Engage in impactful public health data analysis, utilizing quantitative skills and epidemiological knowledge to enhance surveillance programs and support critical health initiatives...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$140K - $165K *

Elevate your career by driving strategic pricing initiatives and financial analysis. Collaborate cross-functionally to develop business cases, optimize pricing models, and present actionable insights...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$135K - $175K *

Drive criticality safety evaluations and develop safety programs for innovative nuclear fuel recycling. Collaborate with a dynamic team to ensure compliance and enhance safety measures in a fast-paced...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$160K - $192K *

Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$130K - $150K *

Unlock potential by leading the full sales cycle in healthcare, engaging C-suite executives and driving strategic decisions. Leverage your experience to meet quotas, build account strategies, and enha...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$160K - $170K *

Shape the future of pricing strategy by leading complex deal governance and analytics. Collaborate across teams to enhance deal integrity and leverage AI-driven tools for efficient pricing models, ens...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $116K *

Lead the charge in enhancing patient care by managing clinic operations, training staff, and fostering community engagement. Join a collaborative environment focused on continuous learning and quality...

Today

  •   Less than 5 years exp.  •   Healthcare

$150K - $214K *

Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$128K - $145K *

Support the full life cycle of vendor contracts, from negotiation to execution. Collaborate with stakeholders to manage legal risks and ensure compliance in a fast-paced environment, focusing on healt...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $132K *

Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$111K - $167K *

Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$122K - $184K *

Drive operational excellence by leading physician practices in Ohio. Collaborate with clinical and regional teams to enhance performance, accountability, and patient experience while translating data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$78K - $92K *

Engage in impactful virtual counseling for patients with acute mental health conditions. Develop treatment plans, exercise clinical judgment, and collaborate with multidisciplinary teams to enhance be...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$176K - $287K *

Shape the future of oncology by cultivating relationships with KOLs, providing critical insights, and supporting research initiatives. Drive awareness and education while ensuring compliance and integ...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's redefining customer success by leveraging AI to enhance the post-sale journey. Lead and scale a dynamic team while driving retention and expansion for enterprise clients in a fast-p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $224K *

Advance patient outcomes by leveraging your expertise in CNS as a Medical Science Liaison. Collaborate with healthcare providers and stakeholders to deliver evidence-based insights and drive strategic...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion growth by leading national accounts, driving strategy, and enhancing partnerships with specialty distributors and GPOs. Leverage expertise to ensure product availability and exceed corporate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Support patient evaluations by conducting psychological assessments and collaborating with a clinical team to enhance diagnostic outcomes and treatment plans. Leverage expertise in standardized testin...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$177K - $221K *

Manage the strategy and execution of access marketing for oncology products, focusing on value propositions for payers and healthcare providers. Collaborate with cross-functional teams to ensure effec...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $156K *

Empower your career by leading revenue analytics, overseeing financial analysis, and enhancing payer contract strategies. Collaborate with cross-functional teams to optimize reimbursement and drive or...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.