Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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Oncologist Jobs in Iowa

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$150K - $224K *

Unlock potential by engaging with healthcare stakeholders to enhance patient outcomes through strategic medical insights and collaboration within the CNS ecosystem, driving effective utilization of Ot...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$153K - $210K *

Transform your career by partnering with teams to drive strategic growth through legal expertise in healthcare contracts, negotiations, and compliance. Collaborate with leadership to optimize performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $88K *

Accelerate progress at expanding customer accounts by driving annual recurring revenue and enhancing retention through structured sales strategies and digital engagement, while managing a high-volume...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$175K - $200K *

Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Champion project success by leading clinical trials from initiation to closure, ensuring compliance with budgets, timelines, and regulations while fostering collaboration among stakeholders and team m...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $144K *

Lead the charge in delivering exceptional customer service and technical support at assigned medical equipment sites, ensuring compliance with contracts and fostering strong client relationships throu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$210K *

Unlock potential by joining our telemedicine team, where you'll provide compassionate, patient-centered care across Iowa. Enjoy flexible scheduling while managing diverse clinical cases through secure...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Join a team that's redefining healthcare delivery through telemedicine. Provide high-quality, patient-centered virtual care across Iowa, managing diverse clinical cases while enjoying a flexible sched...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Engage with clients to showcase innovative healthcare solutions, driving sales success through impactful demonstrations and expert guidance. Collaborate with sales teams to address client needs and en...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $120K *

Drive impactful research initiatives by leading complex projects, mentoring teams, and securing new business opportunities. Collaborate with diverse stakeholders to deliver high-quality evaluations an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $234K *

Shape the future of advanced analytics and AI, driving data-driven solutions across commercial, medical, and clinical operations. Collaborate cross-functionally to deliver insights, enhance decision-m...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $194K *

Pioneer impactful scientific exchanges as a Senior Medical Science Liaison, fostering relationships with healthcare providers and key opinion leaders in hematology/oncology while supporting Rigel's in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Transform patient care by assisting Gastroenterology faculty in delivering comprehensive diagnostic and therapeutic services, ensuring optimal outcomes for adult patients in outpatient and infusion se...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Unlock potential by shaping innovative solutions for Opioid Treatment Programs and Medication Assisted Treatment. Collaborate with clients and teams to translate complex needs into actionable product...

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4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$124K - $171K *

Accelerate sales growth by managing and qualifying strategic Enterprise Intelligence opportunities. Collaborate with cross-functional teams, ensuring comprehensive engagement and communication to opti...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$201K - $251K *

Transform workforce intelligence by leading People Analytics, establishing data governance, and driving strategic decision-making in a high-growth environment. Collaborate across functions to enhance...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Engage with a dynamic CRO to oversee clinical monitoring and enhance site performance. Foster relationships, ensure compliance with regulations, and lead a team in delivering quality outcomes in clini...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $115K *

Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving sales strategy and value analysis, partnering with cross-functional teams to enhance proposals, pricing, and contracts. Lead market research and client engagement to optimi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Elevate your career by providing clinical support and training for patient monitoring systems. Lead implementation teams, ensure customer satisfaction, and maintain clinical expertise while managing t...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $103K *

Shape the future of revenue cycle management by driving process improvements and reducing denials. Collaborate with teams to analyze trends, implement best practices, and enhance client satisfaction t...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$225K - $250K *

Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$81K - $94K *

Join a team that's dedicated to providing holistic outpatient clinical services. This role involves conducting assessments, therapy, and crisis intervention while ensuring compliance with clinical gui...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.