Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$210K *

Empower patients through innovative telehealth solutions. Join our team of board-certified OB/GYN physicians to deliver high-quality, patient-centered care across Iowa, balancing flexibility with clin...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Engage in a rewarding telehealth role, providing compassionate care across various clinical cases. Enjoy flexible scheduling while delivering high-quality virtual consultations to patients throughout...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic team to enhance decision-making and support EHRM initiatives. Drive program management, facilitate stakeholder engagement, and contribute to strategic communications while ensuring effe...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving partnerships within health systems, building strategic relationships, and creating impactful ecosystems that accelerate product adoption and streamline sales cycles, while...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $160K *

Contribute to the evolution of data-driven healthcare products, shaping strategy and execution. Collaborate with cross-functional teams to deliver AI-enabled solutions that enhance clinical outcomes a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$149K - $202K *

Make your mark at the forefront of patient access marketing, leading strategies and initiatives to enhance the Bone portfolio experience. Collaborate cross-functionally to optimize access solutions an...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$148K - $222K *

Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Empower a high-performing sales team to drive strategic growth and customer engagement in the biopharma sector. Lead complex sales initiatives, build executive relationships, and translate business st...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $195K *

Shape the future of cardiovascular care by driving the launch of a novel cardiac myosin inhibitor. Collaborate with healthcare professionals and internal teams to establish strategic relationships and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$84K - $99K *

Join a dynamic team to evaluate and process medication prior authorization requests, ensuring compliance with clinical guidelines and regulatory standards while facilitating timely patient access to n...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $146K *

Partner with us to provide clinical support for contrast media, delivering education and product expertise to healthcare professionals while collaborating with internal teams to enhance patient care a...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Serve as the primary contact for clients, driving engagement and service quality while fostering relationships with key stakeholders and leveraging expertise to enhance organizational growth and clien...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Lead corporate legal strategy and M&A transactions, guiding complex deals and governance. Manage a growing legal team, develop processes, and partner with senior leadership to drive business initiativ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$199K - $269K *

Grow your career with a leadership role in AI Digital Product Management, driving strategy and innovation across a portfolio of AI products. Collaborate with cross-functional teams to deliver scalable...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $150K *

Elevate healthcare performance by leading analytics-driven consulting engagements. Collaborate with clients to identify needs, deliver insights, and implement solutions while managing project economic...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $112K *

Join a team that's dedicated to advancing clinical research by ensuring high standards of care and compliance in monitoring clinical trials. Leverage your expertise in oncology and clinical monitoring...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Develop and lead regional strategies to drive product launch success, ensuring alignment with corporate goals. Build a high-performing team, foster customer relationships, and execute data-driven deci...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$141K - $191K *

Champion high-impact scientific communication strategies, collaborating across Medical Affairs and Commercial. Lead content development, enhance engagement, and drive operational excellence for effect...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Lead the charge in shaping detection and response strategies, driving hands-on initiatives to enhance security architecture and incident management. Collaborate across teams to ensure robust threat de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's advancing oncology solutions by managing global clinical trials. Lead project execution from protocol development to study closeout, ensuring quality and compliance while fostering...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Transform provider engagement by leading peer-to-peer conversations and ensuring clinical governance. Leverage your medical expertise to enhance patient safety and optimize drug strategies while repre...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Drive evidence-based healthcare improvements by leading evaluations and strategic analyses. Collaborate with multidisciplinary teams to enhance Military Health System outcomes through expert consultat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$204K - $340K *

Lead the charge in generating impactful real-world evidence to support oncology products, ensuring alignment with market needs and regulatory requirements while collaborating across teams to drive evi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.