Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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1,000+

Oncologist Jobs in Alabama

Sort By: Relevance

$156K - $211K *

Unlock your potential as a Senior Machine Learning Engineer, driving innovative AI solutions. Collaborate with cross-functional teams to develop scalable prototypes, translating complex business needs...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$98K - $155K *

Accelerate progress at the forefront of value-based care by leading strategic partnerships, driving growth innovation, and optimizing performance across national health plans and ACOs while mentoring...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $139K *

Join a team that's dedicated to driving excellence in clinical trial contracts. As a Senior Site Contracts Manager, you'll negotiate and manage site budgets and agreements, collaborating with key stak...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$58K - $105K *

Unlock your potential by managing the full contracting lifecycle, supporting critical agreements for Medicare Advantage and Commercial operations, while collaborating with diverse teams to enhance com...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $215K *

Transform regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$143K *

Join a team that's redefining virtual healthcare by delivering high-quality, patient-centered care. As a key member, you'll provide comprehensive virtual medical services, collaborate with stakeholder...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Shape the future of cybersecurity by monitoring and responding to real-time threats, conducting forensic analysis, and enhancing national security through proactive defense strategies and incident man...

Today

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Empower government contract management by overseeing the full lifecycle, ensuring compliance, and mitigating risks while supporting internal stakeholders and government customers effectively...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $100K *

Reimagine talent acquisition by leading full-cycle recruiting efforts, collaborating with leadership to forecast hiring needs, and enhancing employer branding to attract top talent while ensuring comp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Innovate your career by leading SAP S/4HANA transformations, guiding clients through Order to Cash solutions, and enhancing operational efficiency while establishing strong partnerships and delivering...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Champion data-driven decision-making by transforming complex marketing insights into actionable recommendations. Collaborate with clients and teams to enhance reporting solutions and drive campaign su...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Empower our finance team by overseeing accounting operations, ensuring compliance, and enhancing financial reporting. Lead month-end close activities and mentor team members in a dynamic, multi-entity...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock your potential by analyzing Medicaid data to enhance program performance, quality, and access. Collaborate with diverse teams to develop insights that drive impactful decisions in healthcare an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Empower life sciences innovation by evaluating AI model outputs, ensuring quality and accuracy. Collaborate with cross-functional teams to enhance predictive analytics and insights, bridging clinical...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in developing and overseeing scientific content across multiple therapeutic areas, ensuring high-quality contributions and strategic client interactions to drive growth and innovation...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$67K - $173K *

Transform project controls for major capital programs, ensuring compliance and driving efficiency. Lead diverse teams to deliver critical assets in manufacturing, focusing on safety, cost, and quality...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the development and execution of Immunology access services strategy, ensuring seamless patient and provider experiences. Collaborate cross-functionally to enhance reimbursement initiatives and d...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $188K *

Unlock potential by leading product strategy and management for diverse lines, ensuring customer needs drive innovation while aligning with corporate goals. Collaborate with cross-functional teams to...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Unlock potential by overseeing clinical trials, ensuring compliance with protocols and regulations. Collaborate with investigators and coordinators to protect participant rights and verify data integr...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$147K - $220K *

Champion transformative health solutions by managing key client relationships, driving sales, and collaborating across teams to enhance Verily's impact in Life Sciences. Leverage expertise to unlock n...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $200K *

Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$320K - $400K *

Contribute to a dynamic team as a Board Certified Orthopaedic Surgeon specializing in Total Joint procedures. Leverage advanced technology and strong support systems to deliver exceptional patient car...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.