Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,758

Sort By: Relevance

$150K - $180K *

Lead the charge in global expansion strategy for an innovative English language assessment solution. Drive international partnerships, attract investors, and expand market presence across established...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$149K - $299K *

Engage as a strategic partner to the COO, driving operational excellence and performance transformation across the organization through data-driven decision-making and continuous improvement initiativ...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Join our team as a Senior Systems Analyst Epic to optimize healthcare IT applications. Collaborate with stakeholders to design, implement, and support Epic systems that enhance clinical and operationa...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$80K - $150K *

Unlock potential by driving hardware security assessments, improving client security postures, and delivering actionable insights. Collaborate with teams and engage directly with clients while enhanci...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$60K - $129K *

Grow your career with a remote Case Manager RN role, focusing on patient advocacy, care coordination, and clinical assessments to ensure optimal health outcomes while managing multiple priorities in a...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$184K - $396K *

Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$66K - $142K *

Manage comprehensive case management processes to assess, plan, and advocate for patient needs, ensuring optimal health outcomes through effective communication and resource utilization in a fully rem...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of aggregate production by overseeing operations, ensuring safety compliance, managing budgets, and leading personnel across multiple facilities to achieve efficiency and profitabilit...

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$169K - $220K *

Champion backend innovation by architecting scalable systems and guiding a team of engineers. Leverage cutting-edge technologies to optimize user experiences and deliver impactful solutions in a colla...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$123K - $159K *

Elevate customer experiences by leading activation readiness initiatives. Ensure operational excellence through effective training, playbook development, and cross-functional collaboration, driving co...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Oversee security initiatives to protect personnel and assets, developing comprehensive programs and policies. Collaborate with cross-functional teams to enhance security infrastructure and foster a cu...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's shaping water and wastewater solutions, managing engineering for diverse projects. Lead multi-discipline teams, oversee budgets, and mentor staff while driving innovation in sustain...

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$126K - $149K *

Innovate credit risk management strategies by collaborating across teams to enhance portfolio performance, drive effective governance, and identify emerging risks for continual business growth and reg...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$108K - $116K *

Empower your nursing career by utilizing your clinical expertise to assess, plan, and coordinate healthcare services. Collaborate with providers to enhance patient care and promote effective utilizati...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a dynamic team to drive profit and loss performance while ensuring compliance in multiple industrial services environments. Lead operations, manage talent, and build customer relationships to ach...

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $100K *

Drive fraud risk strategies and tools to enhance detection and mitigate losses. Collaborate with teams to balance customer experience and operational impacts while ensuring compliance with regulations...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Help us shape the future of construction financing by leveraging your experience in loan origination. Join our dynamic team and gain direct access to a nationwide market, empowering clients with tailo...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $100K *

Develop and manage fraud risk strategies for commercial accounts, focusing on IT tools to enhance detection and mitigate losses while balancing customer experience and operational impacts. Collaborate...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Engage in a dynamic role overseeing large projects and teams, ensuring successful delivery through effective stakeholder coordination and project management. Contribute to innovative power delivery so...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$65K - $100K *

Lead and develop teams while driving financial performance and enhancing customer service. Collaborate with associates to implement business solutions and foster a culture of continuous improvement an...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Transform healthcare by optimizing Epic applications that ensure safe patient care and enhance operational workflows. Collaborate with cross-functional teams to build, train, and support vital system...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$104K *

Unlock potential by leading HVAC installations and maintenance, ensuring compliance with local codes while training junior technicians and delivering exceptional service to clients in both residential...

Today

  •   Less than 5 years exp.  •   Technical Services

$120K - $150K *

Transform your career by leading a dynamic team to ensure clinical excellence across multiple regions, driving project success through strategic management and collaboration while fostering a culture...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive quality excellence by leading the quality team, improving processes and compliance, and enhancing customer relationships to achieve operational success in a manufacturing setting. Foster a cultu...

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.