Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,760

Sort By: Relevance

$168K - $285K *

Elevate the future of software planning by leading a team that integrates human and AI collaboration. Shape product direction, connect work to business priorities, and drive strategic decisions in a d...

United StatesRemote

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  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's redefining cloud reliability by enhancing observability, automation, and operational excellence. Collaborate across departments to ensure seamless deployment and management of SaaS...

United StatesRemote

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  •   Less than 5 years exp.  •   Information Technology

$120K - $155K *

Contribute to Oracle database modernization by assessing, planning, and executing migration strategies. Collaborate with technical teams to optimize performance and ensure successful data migration in...

United StatesRemote

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  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Drive data-driven decision-making by transforming complex data into actionable insights. Collaborate with cross-functional teams to enhance reporting and analytics using advanced SQL and AI tools, ens...

United StatesRemote

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  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $180K *

Drive your career with a dynamic role leading a sales team across the Great Lakes Region. Foster dealer relationships, enhance team performance, and achieve growth in a fast-paced environment while ma...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$174K - $215K *

Lead a dynamic team to drive business performance in hematology/oncology, focusing on metastatic breast cancer. Develop strategies for patient access and treatment, ensuring compliance and collaborati...

United StatesRemote

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  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$66K - $169K *

Lead product quality initiatives to ensure compliance and continuous improvement throughout the product lifecycle, partnering with cross-functional teams to enhance manufacturing performance and suppo...

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  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $245K *

Empower the oncology portfolio strategy by driving regional marketing initiatives, fostering KOL relationships, and executing launch tactics to optimize product adoption and customer engagement across...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...

United StatesRemote

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  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in advancing F-22 modernization efforts by managing complex acquisition programs, collaborating with military stakeholders, and ensuring effective resource allocation to enhance operat...

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$95K - $115K *

Help us accelerate progress at the forefront of defense technology by designing and developing scalable software solutions in a collaborative Agile environment, enhancing national security missions th...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $140K *

Champion the proposal process by leading submissions, coordinating resources, and ensuring strategic alignment. Drive improvements in proposal development while fostering collaboration across teams to...

United StatesRemote

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  •   5 - 7 years exp.  •   Information Technology

$116K - $151K *

Shape the future of distribution systems by leading construction and maintenance efforts, ensuring safety and reliability while managing budgets and resources effectively to meet customer needs and re...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$162K - $194K *

Drive growth as a Senior Product Marketing Manager, shaping messaging and campaigns for Observability products. Collaborate with cross-functional teams to enhance customer engagement and retention thr...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Shape the future of industrial and data center projects by leading the entitlement process, navigating regulatory landscapes, and ensuring timely approvals. Collaborate with teams and consultants to d...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$122K - $183K *

Transform the aerospace certification landscape by leading process development, ensuring compliance with DO-178C standards, and collaborating with cross-functional teams to deliver high-quality softwa...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by managing Salesforce CRM implementations and configurations. Collaborate with teams to enhance user experience and ensure compliance with cybersecurity policies while providing exce...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$46K - $122K *

Lead the charge in implementing health insurance projects by collaborating with teams, analyzing client needs, and ensuring successful onboarding. Foster relationships and provide mentorship to drive...

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Accelerate your career by driving operational excellence and strategic improvements. Collaborate with leadership and cross-functional teams to enhance customer experiences and optimize processes in a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Unlock potential by driving sales growth and client relationships in a dynamic territory. Collaborate with teams to deliver tailored solutions, mentor staff, and ensure exceptional customer service wh...

Today

  •   Less than 5 years exp.  •   Transportation

$130K *

Analyze and enhance cost accounting practices across manufacturing operations, leveraging Oracle ERP expertise to drive process improvements and financial insights. Collaborate with cross-functional t...

United StatesRemote

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  •   5 - 7 years exp.  •   Business Services

$124K - $158K *

Empower patient health by managing pharmacy operations, ensuring safe dispensing, and leading a dedicated team. Collaborate with healthcare professionals to enhance patient experiences and outcomes wh...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$152K - $254K *

Shape the future of behavioral health by leading clinical programs, driving strategic initiatives, and fostering cross-functional partnerships to enhance member outcomes and operational excellence...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion data-driven decision-making by bridging clinical operations and analytics. Lead projects, deliver actionable insights, and enhance performance across clinics while managing stakeholder commun...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$75K - $109K *

Advance the future of Building Information Modeling by leading BIM strategies, ensuring model quality, and mentoring teams. Drive innovation through technology initiatives and enhance project delivery...

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  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.