Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,752

Sort By: Relevance

$144K - $189K *

Unlock potential by leading product innovation in clinical genomics. Shape tools for case management and data workflows, ensuring efficiency and quality while collaborating with lab directors and engi...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the safety implementation of an Environmental, Safety, and Health program, ensuring compliance and managing occupational safety for projects. Collaborate with teams to enhance safety practices an...

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $105K *

Provide comprehensive support for the Environmental, Safety, and Health program, ensuring compliance with regulatory standards and enhancing workplace safety measures through data analysis and stakeho...

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Innovate with us to build scalable legal frameworks that support rapid growth. As a strategic advisor, you'll manage complex agreements, corporate governance, and leverage AI to enhance operational ef...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$275K - $325K *

Lead the charge in building and managing a construction banking sector, driving strategy, partnerships, and product development while overseeing P&L and fostering key relationships to establish Flex a...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in advancing enterprise automation capabilities, driving quality engineering innovation, and influencing strategic decisions across a rapidly growing organization, enhancing software r...

US-AnywhereRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's shaping scalable backend systems to enhance pharmacy operations with AI-driven solutions, driving performance and reliability while mentoring engineers and influencing technical dir...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Grow your career with a dynamic role that bridges business needs and IT solutions, ensuring high-quality application performance and process improvements while collaborating with stakeholders to enhan...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Collaborate on strategic global purchasing efforts for capital equipment. Manage CAPEX transactions, lead contract processes, and support operations with financial assessments and compliance. Foster r...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Shape and drive strategic Innovation and Renovation projects, ensuring flawless execution from concept to completion. Lead cross-functional teams to meet key performance indicators while fostering col...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$83K - $102K *

Unlock potential by joining a dynamic team focused on data-driven project controls. Collaborate with cross-functional stakeholders to develop automated data flows and insightful dashboards, enabling i...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$109K - $197K *

Elevate your career by optimizing performance in large-scale enterprise applications. Join a dynamic team focused on enhancing user experience through innovative solutions and expert analysis of compl...

Today

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Champion vehicle platform design by leading a multifunctional team to fulfill quality, performance, and safety standards, while ensuring alignment with customer requirements and strategic goals...

Reposted today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$130K - $155K *

Lead and inspire a talented engineering team to innovate vehicle platforms, ensuring quality and performance standards are met while fostering strong supplier partnerships and collaboration across dep...

US-AnywhereRemote

Reposted today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$68K - $103K *

Empower your career by coordinating Epic optimization initiatives, managing requests, and facilitating collaboration across teams. Drive project success through effective communication and oversight...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Unlock your potential by leading regional waste management operations, ensuring compliance, optimizing efficiency, and driving sustainability initiatives across multiple sites while managing budgets a...

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$89K - $133K *

Empower success by leading healthcare technology implementations, optimizing workflows, and ensuring compliance. Collaborate across teams to guarantee smooth integrations and enhance system functional...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $200K *

Lead the charge in vulnerability management, driving remediation efforts and enhancing security across cloud environments. Collaborate with cross-functional teams to reduce risks and improve operation...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Join a dynamic team to advance small UAS capabilities, ensuring integration and performance across complex systems. Leverage your expertise in systems engineering and contribute to critical defense in...

Today

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Partner with us to lead and engineer complex projects, providing technical guidance and mentoring to junior engineers while ensuring design standards and solutions meet specifications across various s...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$165K - $200K *

Lead the charge in driving sales excellence and team development across a dynamic region. Oversee a team of Territory Managers, implement strategic initiatives, and collaborate cross-functionally to a...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive new account development and enhance customer relationships by leveraging Summit's competitive advantages. Collaborate across departments to promote solutions, resolve issues, and adapt strategie...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$72K - $90K *

Optimize immersive learning experiences for Cincinnati Innovation District partners. Lead project management, build relationships, and ensure quality delivery of educational workshops and programs to...

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $102K *

Champion clinical research initiatives by overseeing complex studies, ensuring compliance, and collaborating with diverse teams to enhance patient care and research outcomes in the Emergency Medicine...

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.