Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,752

Sort By: Relevance

$175K - $200K *

Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading product strategy and development, collaborating across teams to drive market success. You'll oversee product roadmaps, manage budgets, and enhance customer engagement while...

Today

  •   Less than 5 years exp.  •   Technical Services

$85K *

Join a dynamic 6-month program designed for recent engineering graduates to develop technical sales skills. Gain hands-on experience, mentorship, and build relationships while supporting sales activit...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$74K - $203K *

Drive integration excellence by overseeing OIC implementations and collaborating with stakeholders to enhance enterprise applications. Play a key role in optimizing performance and ensuring seamless c...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$114K - $167K *

Drive impactful SAP BRIM projects by leading cross-functional teams, managing client relationships, and ensuring project alignment with business goals. Foster innovation and quality while optimizing r...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Shape your career with impactful EHS leadership by overseeing safety and compliance initiatives across multiple sites, coaching teams, and driving sustainability efforts to enhance workplace safety an...

Reposted today

  •   5 - 7 years exp.  •   Transportation

$149K - $205K *

Lead the charge in delivering innovative engineering solutions across multiple factories, ensuring alignment with strategic initiatives and operational excellence while fostering collaboration and tec...

Today

  •   8 - 10 years exp.  •   Food & Beverages

$81K - $109K *

Drive category growth by managing key customer accounts, achieving sales targets, and fostering strong relationships. Collaborate with cross-functional teams to execute strategic business plans and en...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$119K - $163K *

Transform the future of bioinformatics by developing innovative algorithms for analyzing large-scale genomic datasets, collaborating with scientists to drive research from prototype to clinical valida...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $151K *

Join a team that's responsible for overseeing complex Generation Projects. Lead engineering activities through the project lifecycle, ensuring safe, efficient delivery of utility-scale power generatio...

Reposted today

  •   8 - 10 years exp.  •   Energy & Utilities

$150K - $175K *

iCapital is seeking a Regional Senior Vice President or Managing Director to lead the Midwest market's Alternative Investment sales team. This role involves overseeing a team, developing client relati...

US-AnywhereRemote

Reposted today

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Advance operational excellence by leading a dynamic team to optimize production, enhance efficiency, and ensure compliance in a fast-paced manufacturing environment. Drive continuous improvement initi...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Engage with strategic accounts by leading a dynamic team of Technical Account Managers, enhancing customer relationships and driving satisfaction through tailored strategies and exceptional service, e...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Drive the future of technical sales leadership by managing a team of Solutions Engineers, enhancing enterprise adoption of cutting-edge technologies, and ensuring technical wins through strategic part...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Unlock potential by driving strategic insights and operational excellence in a dynamic environment. Collaborate across teams to analyze complex problems, shape pricing strategies, and support market e...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Drive the development of innovative data-driven software solutions that enhance engineering analysis and decision-making. Collaborate with teams to design, build, and maintain full-stack applications...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$102K - $147K *

Drive new business opportunities by cultivating relationships with C-level executives. Own the full sales cycle for Large Enterprise clients, ensuring value delivery and exceeding sales targets while...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Manage the full sales cycle to open new mid-market and enterprise accounts, develop cross-sell opportunities, and grow customer relationships through high-value cybersecurity services, ensuring commer...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$116K - $193K *

Pioneer innovative EHR strategies by leading cross-functional teams to enhance interoperability, optimize workflows, and drive measurable outcomes in healthcare delivery. Collaborate with diverse stak...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$230K - $300K *

Lead global Strategic Marketing initiatives, driving segment strategies, customer insights, and go-to-market planning to enhance organizational capability and revenue growth across diverse markets...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Business Services

$250K - $325K *

Champion the development and execution of innovative sales enablement programs, collaborating with cross-functional teams to enhance training, elevate performance, and drive growth in the competitive...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$188K - $314K *

Shape the future of our technology ecosystem by leading engineering teams, driving innovation, and aligning technology strategy with business goals to enhance customer experiences and operational effi...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Finance & Insurance

$85K - $102K *

Lead the charge in managing complex projects, ensuring successful execution from initiation to closeout. Collaborate with teams, track progress, and adapt to changes while meeting organizational objec...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$217K - $310K *

Elevate your career by leading investor relations and strategic finance initiatives. Collaborate with executives to craft compelling narratives, build investor relationships, and drive impactful finan...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$105K - $130K *

Transform patient care by delivering high-quality primary and palliative services. Collaborate with a dedicated team to assess, diagnose, and treat diverse patients, ensuring optimal health outcomes i...

Today

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.