Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,757

Sort By: Relevance

$143K - $185K *

Unlock potential by leading clinical data management for innovative cell therapy studies. Collaborate cross-functionally to ensure data integrity and compliance while managing teams and external partn...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K *

Join a team that's committed to excellence in logistics. As a Class A CDL Truck Driver, you'll deliver across multiple states, ensuring safety and compliance while enjoying competitive pay and benefit...

Today

  •   Less than 5 years exp.  •   Transportation

$100K - $130K *

Lead on-site management for industrial/petrochemical projects, ensuring safety, efficiency, and successful completion. Collaborate with crews and clients while overseeing daily operations and project...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $130K *

Lead on-site management for industrial projects, ensuring safety, efficiency, and client satisfaction. Oversee crew operations, manage resources, and drive project completion while maintaining quality...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $97K *

Unlock your potential as you drive customer success in Higher Education. Build trusted relationships, manage strategic accounts, and ensure satisfaction through effective collaboration and tailored su...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $130K *

Lead the charge in managing on-site operations for industrial projects, ensuring safety, efficiency, and successful completion while coordinating multiple crews and liaising with clients to meet proje...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$142K - $189K *

Transform enterprise client relationships by driving strategic growth, orchestrating tailored solutions, and ensuring alignment with corporate standards. Collaborate with cross-functional teams to add...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Business Services

$112K - $186K *

Shape the future of organizational strategy as a trusted advisor, driving execution of initiatives and enhancing leadership effectiveness across teams. Collaborate to navigate complexity and foster in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Accelerate the deployment of innovative manufacturing processes for oncology products, ensuring compliance and collaboration across teams. Lead technology transfers and facility readiness to enhance p...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $190K *

Join a team that's dedicated to advancing precision medicine by leveraging AI to provide cutting-edge educational support and scientific expertise on cancer biomarker tests while engaging key opinion...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$113K - $140K *

Champion the reliability and performance of critical systems, driving architecture evolution and incident response. Collaborate with a skilled team across AWS and Azure, ensuring security and scalabil...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$72K - $125K *

Join a dynamic team to design, develop, and implement software solutions that address business needs. Collaborate on agile projects, mentor junior engineers, and enhance system performance while ensur...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$85K - $90K *

Advance your career by maintaining and optimizing laser equipment across multiple clinics. You'll ensure operational excellence and reliability, serving as a vital link between clinical teams and equi...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Drive technical excellence in Colleague SaaS implementations, collaborating with clients and teams to enhance system performance and optimize higher education information systems. Lead projects from a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $90K *

Join a team that's dedicated to maintaining and optimizing laser equipment across multiple clinics. You'll ensure operational excellence and equipment reliability, playing a vital role in supporting c...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a dynamic team as you drive sales growth by cultivating client relationships and executing strategic marketing initiatives. Leverage your consultative skills to provide tailored workforce solutio...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $90K *

Transform clinic operations by ensuring optimal performance of laser equipment across multiple locations. You'll play a key role in maintaining reliability and readiness, bridging clinical teams with...

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Engage with enterprise clients to drive sales growth through strategic prospecting, relationship building, and consultative solutions. Collaborate with brokers and leverage marketing strategies to exc...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in a dynamic environment, driving sales and technical support for innovative insulating products while fostering relationships with key industry players and enhancing customer satisfac...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $180K *

Transform the future of cloud infrastructure by leading DevOps initiatives, enhancing systems integration, and driving innovative solutions for federal clients. Collaborate with stakeholders to optimi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock potential by leading the General Accounting function, ensuring accurate financial reporting and robust internal controls while driving continuous improvement and team development in a dynamic e...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead and enhance the General Accounting function, ensuring accurate financial reporting and robust internal controls while driving continuous improvement and team development in a dynamic environment...

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $140K *

Join us in transforming digital services for Veterans. As a Senior Designer, you'll lead user experience initiatives, conduct research, and shape information architecture for a large digital portal, e...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $94K *

Engage in technical support and troubleshooting for production lines, ensuring quality and efficiency. Collaborate on design improvements and conduct testing to enhance product performance while adher...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$154K - $221K *

Lead the charge in shaping the sales engineering team for core solutions, driving revenue growth through strategic partnerships and innovative problem-solving in a dynamic environment...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.