Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs offering salaries of $100,000 or more, from leadership positions to specialized roles. Whether you’re targeting a new opportunity in Columbus, Cleveland, Cincinnati, or another Ohio community, find openings that match your experience and career goals.

Find Opportunities Across Ohio

Ohio’s job market spans major metropolitan areas and a wide range of industries. Search roles in cities such as Columbus, Cleveland, and Cincinnati, as well as opportunities throughout the state. Availability varies by employer and location, so explore current listings to see where your skills are in demand.

Explore Professional Roles and Industries

High-paying Ohio openings may include positions in technology, healthcare, finance, manufacturing, sales, and operations. Listings can range from experienced individual-contributor roles to director, vice president, and executive positions. Review each posting for its responsibilities, qualifications, location, and compensation details.

Make Your Ohio Job Search More Focused

Use Ladders to narrow your search by role, location, and other preferences. Tailor your resume to highlight relevant achievements, leadership experience, and measurable results. Check listings regularly and apply to opportunities that align with your qualifications and compensation expectations.

Discover Your Next Career Move

Find vetted professional jobs paying $100,000 or more in Ohio on Ladders. Browse current openings and take the next step toward a role that fits your experience and ambitions.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,757

Sort By: Relevance

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

RemoteRemote

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  •   5 - 7 years exp.  •   Healthcare

$246K - $332K *

Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...

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  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$219K - $285K *

Shape and lead a centralized commercial analytics function, transforming complex data into actionable insights. Drive performance measurement, growth identification, and strategic decision-making acro...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$235K - $350K *

Transform the future of cyber defense by architecting cutting-edge AI systems that autonomously protect against real-world threats. Lead technical direction, mentor teams, and drive innovation from re...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$100K - $145K *

Elevate your career by managing Kubernetes clusters across diverse environments. Collaborate with senior engineers to automate processes, troubleshoot issues, and enhance platform performance while de...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Lead asphalt plant operations to optimize safety, production, and team performance while driving continuous improvement and managing capital projects to support growth objectives...

Today

  •   15+ years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate pharmacy operations by managing a dynamic team, ensuring compliance with regulations, and optimizing financial performance in oncology and ambulatory infusion settings. Drive excellence in pat...

Today

  •   Less than 5 years exp.  •   Healthcare

$174K - $234K *

Shape the future of Hematology analytics by leading strategic insights and performance initiatives. Collaborate with cross-functional teams to enhance field execution and drive commercial success thro...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$133K - $173K *

Drive compliance excellence by managing global monitoring programs and investigations. Collaborate with stakeholders to enhance compliance infrastructure and ensure adherence to regulations, while lea...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $140K *

Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$121K - $206K *

Lead the charge in architecting and delivering Microsoft Azure and 365 solutions for SMBs. Oversee cloud migrations, security implementations, and project management while fostering strong partner rel...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$97K - $165K *

Shape the future of cloud solutions by leading technical relationships, validating AWS architectures, and driving presales strategies. Empower teams through mentorship while ensuring secure, scalable...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$74K - $124K *

Elevate compensation strategies by transforming complex data into actionable insights. Collaborate with stakeholders to manage compensation programs, analyze trends, and recommend solutions that ensur...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $138K *

Pioneer innovative construction solutions by managing multiple projects, ensuring quality, budget adherence, and timely completion while collaborating with contractors and internal teams to achieve de...

Ohio, USRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$485K *

Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitality & Recreation

$162K - $207K *

Lead the charge in implementing and optimizing SAP Vistex solutions, translating business strategies into technical architecture while managing cross-functional teams and project deliverables for enha...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead the charge in advancing clinical excellence by managing a team of APPs, fostering collaboration, and ensuring high-quality patient care across multiple sites while maintaining a hands-on clinical...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing quality and safety in healthcare. This role involves leading multidisciplinary projects, educating staff, and implementing continuous improvement initiatives...

Today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Transform healthcare by collaborating with physicians to provide critical care in an inpatient setting. Utilize advanced clinical skills to enhance patient outcomes and support surgical teams in a dyn...

Today

  •   Less than 5 years exp.  •   Healthcare

$129K - $185K *

Unlock potential by leading the Customer Identity & Access Management function, overseeing CIAM platform operations, and driving identity strategy across global digital ecosystems while collaborating...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in aligning HR strategies with business goals, enhancing organizational effectiveness and employee engagement while navigating complex labor relations in a unionized manufacturing envi...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $180K *

Shape your career by developing strategic sales plans, conducting impactful presentations, and building strong relationships to achieve sales goals in the pharmaceutical sector while adhering to ethic...

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  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Unlock potential by developing effective strategies and relationships to drive sales growth in the territory, ensuring compliance with regulations and high levels of customer engagement through effect...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Engage with targeted customers to drive sales growth through strategic planning, effective presentations, and relationship building while adhering to ethical practices and achieving quarterly goals in...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, senior, leadership, and executive roles across fields such as technology, healthcare, finance, manufacturing, sales, and operations. Available positions vary, so check current postings for details.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, and other Ohio communities. Search by location to see current openings near you or in a city where you’d like to work.

  • How can I find Ohio jobs that pay at least $100,000?question toggle

    Browse Ohio listings on Ladders and review each posting’s compensation information, location, and qualifications. Use available search filters to focus on roles that fit your experience and goals.

  • Are all Ohio jobs on Ladders remote or on-site?question toggle

    Work arrangements vary by employer and position. Review each listing for its location and whether it describes the role as on-site, hybrid, or remote.