Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,319

Sort By: Relevance

$110K - $130K *

Join a team that's redefining global sourcing strategies for machined parts and outside processing. Drive supplier relationships, negotiate contracts, and enhance cost efficiency while collaborating a...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$212K - $287K *

Join us to lead and develop a high-performing sales team in Hematology, driving sales excellence and strategic initiatives while ensuring compliance and integrity across the Great Plains region...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion pricing strategy development and execution to drive profitable growth. Collaborate cross-functionally to optimize pricing governance and enhance commercial effectiveness, transforming pricing...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate clinical operations by leading urgent care centers, ensuring high-quality patient care and fostering teamwork. Collaborate with medical staff to enhance service efficiency and patient experien...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$184K - $356K *

Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Help us advance literacy education by leading research, teaching, and mentorship in reading and writing. Collaborate with diverse stakeholders to enhance teacher preparation and engage in impactful co...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$189K - $249K *

Drive transformation by leading process excellence and change management teams. Ensure sustainable improvements across business units, optimizing performance and stakeholder experience while fostering...

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $130K *

Advance cardiac surgical care by collaborating with a skilled team of surgeons and APPs. Engage in OR and clinical duties, ensuring high-quality patient outcomes through expert assistance and comprehe...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $170K *

Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$61K - $122K *

Optimize project coordination by leading packaging initiatives that enhance nutrition product development. Collaborate with cross-functional teams to ensure timely execution and quality outcomes, whil...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $189K *

Lead the charge in delivering exceptional pharmaceutical care by interpreting prescriptions, consulting with patients, and ensuring quality assurance. Collaborate with healthcare professionals to opti...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower developers by diagnosing and resolving complex technical issues related to APIs. Collaborate across teams, advocate for improvements, and enhance developer experiences in a fast-paced, innovat...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$129K - $192K *

Champion business growth by leading strategic development for Durables applications. Collaborate with cross-functional teams and customers to drive innovation, clarify needs, and build a robust opport...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$129K - $192K *

Unlock potential by leading strategic business development for Durables, bridging customer needs with cross-functional teams to drive growth and innovation in North America. Build relationships and de...

Mentor, OHRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$195K - $325K *

Unlock the future of AI in healthcare by leading multi-year strategies and technical solutions across teams. Drive innovation, influence executive decisions, and shape governance policies while mentor...

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$195K - $325K *

Join a team that's shaping the future of AI in healthcare by leading multi-year strategies, resolving complex technical challenges, and influencing executive decisions across the organization to ensur...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a dynamic team to develop and enhance SaaS applications, utilizing Agile methodologies. Collaborate with peers, support customers, and drive innovative solutions while staying updated on technica...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$65K - $96K *

Advance leadership development by designing impactful programs and coaching talent. Collaborate with teams to enhance learning experiences and drive measurable success in succession planning and organ...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $196K *

Shape the future of K-12 education by leading product marketing strategies that drive growth and adoption. Collaborate cross-functionally to deliver compelling messaging and go-to-market initiatives t...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$170K - $210K *

Elevate project management excellence by leading design coordination for OFCI mechanical systems in a dynamic data center environment, ensuring seamless integration and adherence to technical standard...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.