Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,313

Sort By: Relevance

$135K - $155K *

Lead treasury and investment functions, ensuring financial stewardship and strategic growth. Collaborate across teams, manage relationships, and optimize portfolio performance while aligning investmen...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in advancing F-22 modernization efforts by managing complex acquisition programs, collaborating with military stakeholders, and ensuring effective resource allocation to enhance operat...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $185K *

Shape the future of oncology solutions by leading product strategy and execution for a groundbreaking genomic profiling product line, driving innovation and enhancing patient care through cross-functi...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower innovation by enhancing our Kubernetes platform through design, implementation, and optimization. Collaborate with teams to ensure security, scalability, and reliability while driving continuo...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $115K *

Help us accelerate progress at the forefront of defense technology by designing and developing scalable software solutions in a collaborative Agile environment, enhancing national security missions th...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$74K - $109K *

Join a dynamic team to apply your engineering expertise in solving complex problems, coordinating projects, and enhancing processes while providing guidance to junior staff in a collaborative environm...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $130K *

Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $172K *

Transform customer experiences by providing expert technical support, troubleshooting issues, and implementing scalable solutions. Collaborate with global teams to enhance service delivery and ensure...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $190K *

Shape the future of our legal operations by leading in-house legal efforts, managing contracts, advising on compliance, and collaborating with leadership to drive strategic initiatives across commerci...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $250K *

Unlock your potential by leading product strategy for innovative Java solutions. Shape the future of enterprise SaaS with a focus on performance, optimization, and customer success. Collaborate with e...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $159K *

Analyze and build evaluation frameworks for AI agents, ensuring quality and performance meet client and business standards. Collaborate with cross-functional teams to establish testing methodologies a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $90K *

Unlock potential by exploring various technology disciplines at the Designer I level. Collaborate with mentors, gain hands-on experience, and apply fundamental skills across ICT, Security, AV, and mor...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$69K - $101K *

Grow your career with a dynamic team providing holistic clinical care management services. Collaborate with diverse populations to enhance health outcomes through assessment, care planning, and coordi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$54K - $155K *

Join a team that's transforming mental health delivery through innovative, tech-enabled solutions. Provide 24/7 support via video, chat, or phone, ensuring timely access to high-quality mental health...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Engage in high-level intelligence advising and requirements management, leading enterprise coordination and documentation for critical defense programs. Collaborate with senior leadership to enhance i...

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$126K - $170K *

Elevate your career by driving risk selection and profitability in a dynamic Excess Liability Division. Collaborate with clients and internal teams to deliver tailored insurance solutions while mainta...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$228K - $285K *

Pioneer advancements in AI inference platforms, driving strategy and execution across cross-functional teams to enhance scalability and reliability for enterprise customers. Lead product initiatives f...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$144K - $200K *

Shape the future of enterprise technology by leading transformative consulting engagements. Collaborate with C-level executives to drive strategic initiatives in AI, cloud, and analytics, ensuring imp...

RemoteRemote

3 days ago

  •   11 - 15 years exp.  •   Information Technology

$95K - $115K *

Drive innovation in hypersonic aerothermodynamics by modeling and analyzing advanced systems. Collaborate in a dynamic R&D environment, utilizing high-fidelity CFD applications to tackle complex chall...

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive growth by acquiring new customers for our innovative SaaS solutions. Leverage your sales expertise to engage decision-makers, understand their needs, and promote our Amplify Platform, focusing o...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$112K - $150K *

Shape the PMD performance management process by overseeing operational delivery, coordinating with stakeholders, and ensuring effective execution of performance strategies across the U.S. firm. Drive...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$108K - $130K *

Champion new business growth by leveraging consultative sales strategies to develop tailored solutions for warehousing and manufacturing environments. Collaborate with cross-functional teams to drive...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$73K - $109K *

Collaborate with global teams to drive circularity initiatives, focusing on recyclability, reusability, and compostability of materials. Leverage technical expertise to influence strategies and naviga...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.