Find $100K+ Professional Jobs in Ohio

Explore high-paying professional opportunities across Ohio with Ladders. Browse vetted roles with salaries of $100,000 or more in major employment centers such as Columbus, Cleveland, Cincinnati, Dayton, and Akron. Whether you’re seeking your next leadership position or a specialized role, discover openings across a range of industries and experience levels.

Explore Ohio’s Major Job Markets

Ohio’s diverse economy creates opportunities in metropolitan hubs and communities throughout the state. Search roles in Columbus, a center for business, healthcare, government, and technology; Cleveland, with opportunities in healthcare, manufacturing, finance, and professional services; and Cincinnati, known for corporate headquarters, consumer goods, logistics, and healthcare. You can also explore positions in Dayton, Akron, Toledo, and other Ohio locations.

Industries and Career Paths

Ohio employers hire experienced professionals across industries including healthcare, technology, engineering, manufacturing, finance, sales, operations, and executive leadership. Available positions and compensation vary by employer, role, location, and qualifications. Use search filters to focus on the fields and opportunities that match your career goals.

Find the Right Ohio Opportunity

Review job requirements, responsibilities, location, and compensation details to identify roles that fit your experience. Keep your profile and résumé current, set up job alerts, and check back often to find newly posted opportunities. Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore their next career move in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $125,313

Sort By: Relevance

$150K - $184K *

Lead the charge in enhancing platform security and infrastructure as a Senior Software Engineer. Utilize your Python expertise and SRE mindset to drive critical improvements, mentor teammates, and ens...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Lead the charge in advancing oncology diagnostics by managing a team of bioinformaticians and data scientists, driving product development, and ensuring high-quality analysis and validation of ctDNA-b...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K *

Lead and develop a high-performing SDR team to enhance sales pipeline efficiency, ensuring timely responses and quality prospect engagement through data-driven strategies and collaborative processes w...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower product innovation by driving engineering excellence in new product development, process improvement, and manufacturing efficiency. Collaborate with cross-functional teams to ensure quality an...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Lead the charge in managing electrical installations for utility-scale solar projects. Oversee contractor coordination, ensure quality control, and foster strong relationships while navigating a dynam...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform cybersecurity by leading the enterprise adversary emulation program. Oversee complex attack simulations, validate security controls, and drive improvements across teams to enhance detection...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$119K - $149K *

Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $130K *

Lead comprehensive Medical Loss Ratio examinations, ensuring compliance with ACA regulations. Oversee examiners, manage communications, and analyze data to deliver accurate results. Work remotely in a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$75K - $100K *

Champion the creative process by managing digital ad production, enhancing workflows, and collaborating with cross-functional teams to deliver high-quality marketing assets on time. Drive innovation a...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Optimize enterprise monitoring solutions by administering Dynatrace, enhancing application performance, and ensuring operational observability across diverse environments. Collaborate with teams to im...

Columbus, OHRemote

3 days ago

  •   5 - 7 years exp.  •   Staffing

$144K - $192K *

Drive quality assurance in software development by automating tests and enhancing analytics. Collaborate with cross-functional teams to tackle complex challenges across platforms, ensuring robust prod...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Drive enterprise observability by implementing and optimizing Dynatrace monitoring solutions. Collaborate across teams to enhance application performance, infrastructure monitoring, and incident respo...

3 days ago

  •   5 - 7 years exp.  •   Staffing

$247K - $305K *

Support the strategic commercialization of rare disease therapies by leading marketing initiatives, collaborating cross-functionally, and optimizing brand strategies to enhance patient access and enga...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $190K *

Transform economic insights into strategic decisions by analyzing global markets and trends. Collaborate with leadership to forecast economic conditions and drive data-driven initiatives that enhance...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$121K - $202K *

Shape the future of performance engineering by leading QA delivery for high-transaction healthcare platforms. Drive strategy, mentor teams, and enhance the reliability and scalability of critical syst...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive impactful change by planning and executing complex assignments. Collaborate with teams to analyze data, evaluate systems, and recommend improvements. Take ownership of projects to enhance operat...

3 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$103K - $136K *

Optimize complex casualty claims management by investigating, negotiating, and resolving high-severity cases while ensuring compliance and effective communication with stakeholders to achieve favorabl...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $210K *

Unlock potential by leading HEOR strategy and AI integration, ensuring project success and client satisfaction. Drive business growth, mentor teams, and influence health policy through innovative rese...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$206K - $309K *

Elevate the Analyst Experience by owning strategy and outcomes for security workflows. Lead a team of product managers to unify analyst tools, drive customer migrations, and enhance product vision, en...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$67K - $109K *

Shape the future of retail media by managing end-to-end campaign execution, collaborating with sales and internal teams to drive strategic growth and deliver impactful insights for brand partners...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$127K - $171K *

Join a team that's dedicated to enhancing air quality compliance across AWS data centers. Lead regional programs, provide expert guidance, and collaborate with diverse stakeholders to ensure adherence...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $350K *

Transform client financial futures by providing objective, fee-based advice. Focus on building trusted relationships and delivering comprehensive planning without marketing pressures, ensuring client...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $161K *

Accelerate progress at the forefront of AI solutions by deploying and supporting enterprise AI assistants, ensuring secure and scalable practices while collaborating with clients to drive effective ad...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Lead impactful B2B paid media strategies, optimizing campaigns for top clients. Drive performance, enhance client relationships, and deliver insightful analysis while managing multiple accounts in a f...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Ohio listings may include professional, management, executive, and specialized positions in fields such as healthcare, technology, engineering, manufacturing, finance, sales, and operations. Roles and salaries vary by employer and qualifications.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Opportunities may be available in Columbus, Cleveland, Cincinnati, Dayton, Akron, Toledo, and other Ohio communities. Availability changes as employers post and fill positions.

  • Are the Ohio jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Review each listing for its specific compensation and requirements.

  • How can I find a suitable job in Ohio?question toggle

    Search by location, job title, industry, or other relevant filters. Compare the qualifications, responsibilities, location, and compensation listed for each role, and keep your résumé and profile up to date.