Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,758

Sort By: Relevance

$88K - $105K *

Unlock potential by leading a team of tax professionals, managing complex compliance work, and delivering solutions to minimize client tax liabilities while mentoring staff in a dynamic public account...

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Partner with us to enhance and manage a dealer platform, driving user adoption and optimizing functionality. Collaborate with cross-functional teams to ensure seamless integration and deliver an excep...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$252K - $300K *

Unlock potential by leading the technical strategy for Data Labs, guiding engineering teams to innovate AI training solutions, and shaping the future of model evaluation and deployment in a rapidly ev...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Drive the enterprise ownership of Microsoft 365 services, ensuring optimal performance, security, and compliance. Collaborate with IT teams and external partners to enhance collaboration tools and sup...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $180K *

Drive compliance and legal strategy in a pivotal role, advising leadership while managing risk, privacy, and governance across global operations. Leverage AI tools for efficiency and effectiveness in...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$184K - $230K *

Shape the future of product security by leading architecture reviews and risk mitigation strategies. Collaborate with engineering and compliance teams to embed security throughout the development life...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$108K - $250K *

Elevate your career by driving oncology sales, promoting top-tier products, and enhancing healthcare provider relationships to improve patient outcomes and access within key accounts. Be a pivotal for...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Join a team that's dedicated to transforming health care by delivering exceptional patient care, overseeing pharmacy operations, and fostering a culture of excellence while ensuring compliance and saf...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $165K *

Join us to drive the adoption of a groundbreaking product in cardiovascular care. This dynamic role requires strong sales skills and a commitment to enhancing patient outcomes through collaboration wi...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Partner with us to drive financial strategy and insights, enhancing profitability and resource allocation. Lead budgeting, forecasting, and compliance while influencing cross-functional decisions to o...

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$91K - $112K *

Elevate school culture and scholar success by leading initiatives that foster inclusivity, accountability, and high academic achievement. Collaborate with staff and families to create a safe, supporti...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to delivering accurate financial statements compliant with U.S. GAAP. You’ll drive the preparation and analysis of financial reports, ensuring timely insights and adherenc...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$124K - $157K *

Transform patient care by leading a dedicated pharmacy team, ensuring safety, compliance, and quality service. Drive growth and enhance community health through innovative solutions and compassionate...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team as you lead mobile development in an AI-first environment. Drive innovation, mentor engineers, and shape user experiences across platforms while collaborating closely with product...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$113K - $151K *

Support three senior leaders in a dynamic environment, managing schedules, communications, and logistics while ensuring smooth operations and fostering strong relationships across teams and external p...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$99K - $149K *

Elevate your career by ensuring successful Workday implementations for healthcare clients. Collaborate with a diverse team to deliver tailored solutions, leveraging your expertise in HCM systems and i...

Today

  •   Less than 5 years exp.  •   Consumer Technology

$99K - $149K *

Elevate healthcare outcomes by implementing innovative Workday solutions for clients. Collaborate within a dynamic team to ensure successful deployments tailored to customer needs, leveraging your ind...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Consumer Technology

$88K - $105K *

Join a dynamic team to oversee the implementation of technology programs, ensuring alignment with client needs and regulatory requirements. Collaborate with cross-functional teams to manage documentat...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Transportation

$88K - $105K *

Partner with us to drive operational excellence across multiple facilities, ensuring compliance and quality standards. Oversee revenue-generating centers, analyze performance metrics, and lead strateg...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by ensuring the operational security of information systems. Collaborate with security leadership to manage day-to-day operations and guarantee compliance with security standards f...

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $105K *

Unlock potential by driving strategic sales cycles, acquiring new enterprise customers, and managing complex, multi-solution deals. Collaborate with technical and business stakeholders to tailor solut...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Transform healthcare data by designing and implementing scalable knowledge graph solutions. Collaborate with cross-functional teams to ensure robust technical implementations and optimize graph querie...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$59K - $156K *

Join a team that's transforming data solutions by leveraging Google Cloud Platform expertise. Collaborate on building data pipelines, analytics, and AI models while supporting clients and enhancing yo...

Today

  •   Less than 5 years exp.  •   Business Services

$88K - $105K *

Unlock your potential by leading compliance initiatives in a dynamic environment. Drive regulatory strategies, oversee audits, and collaborate across departments to ensure adherence to quality standar...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$59K - $156K *

Unlock potential by delivering data modernization and AI solutions on GCP. Collaborate with clients, support architecture design, and build data pipelines while enhancing your expertise in data engine...

Today

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.