Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Ohio

Average Salary in USD

Average Salary: $124,752

Sort By: Relevance

$108K - $184K *

Unlock potential by leveraging clinical expertise to enhance pharmacy benefit management, analyze drug trends, and build strong client relationships. Drive strategic recommendations and support client...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $268K *

Unlock potential by leading the design and implementation of cutting-edge CX orchestration platforms, enhancing self-service capabilities and integrating advanced technologies for a seamless customer...

US-AnywhereRemote

Reposted today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$111K - $201K *

Elevate your career as a key IT professional driving the technical design and implementation of advanced CX orchestration platforms. Collaborate with cross-functional teams and take ownership of featu...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$176K - $220K *

Transform the future of genetic medicine by leading translational operations and regulatory integration. Drive cross-functional collaboration, ensure compliance, and enhance program execution to deliv...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$220K - $250K *

Lead enterprise security operations and resilience, driving cyber risk strategy and innovation. Collaborate cross-functionally to embed security principles, modernize defenses, and build high-performi...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$71K - $120K *

Unlock your potential as a Cybersecurity Control Analyst, driving compliance and control assessments while collaborating with diverse stakeholders to enhance our GRC program and strengthen cybersecuri...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Drive the commercial strategy and growth within a rapidly changing environment. Lead a multi-level sales organization, optimizing account planning and CRM processes while fostering teamwork and innova...

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$139K - $208K *

Join a team that's transforming Global Supply Chain and ERP processes. As a Staff Business Process Leader, you'll drive process standardization, support ERP transformations, and engage with stakeholde...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Aerospace & Defense

$110K - $130K *

Optimize and support database platforms, focusing on MySQL and SQL Server migrations to AWS. Lead performance tuning, replication, and maintenance while collaborating with developers to enhance databa...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K *

Take ownership of complex mortgage loan evaluations, ensuring compliance with guidelines while assessing borrower risk. Collaborate with internal teams and vendors to facilitate loan approvals and mai...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Real Estate & Construction

$83K - $140K *

Join a dynamic team to drive insurance product design and implementation. Collaborate cross-functionally to manage projects, ensuring alignment with strategic goals while facilitating effective busine...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $112K *

Lead the charge in clinical trial monitoring, ensuring compliance and data integrity while managing site operations and training staff. Collaborate with teams to deliver high-quality patient care and...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $112K *

Join a team that's dedicated to advancing clinical research by ensuring high standards of care and compliance in monitoring clinical trials. Leverage your expertise in oncology and clinical monitoring...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of plant nutrients by leading integrated strategies across wholesale, specialty, and agronomy sectors. Drive commercial performance, foster collaboration, and unlock efficiencies to e...

Today

  •   8 - 10 years exp.  •   Food & Beverages

$175K - $210K *

Empower your marketing expertise to drive strategy, revenue, and brand positioning across multiple segments. Lead a dynamic team, collaborate with executives, and shape customer advocacy initiatives t...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$136K - $204K *

Transform enterprise marketing by owning ABM strategy, driving pipeline growth, and executing tailored campaigns. Collaborate cross-functionally to engage key accounts and achieve revenue targets thro...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$76K - $98K *

Contribute to innovative civil engineering projects by designing stormwater management systems and collaborating with multidisciplinary teams to deliver sustainable solutions while ensuring compliance...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$70K - $105K *

Collaborate with cross-functional teams to enhance EHR workflows, improve operations, and optimize patient care through effective configuration and analysis of Professional Billing Claims applications...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $225K *

Join a team that's dedicated to delivering innovative tax solutions for sophisticated real estate clients. Lead engagements, mentor staff, and navigate complex tax matters while building strong client...

Today

  •   8 - 10 years exp.  •   Legal & Accounting

$99K - $129K *

Join a team that's transforming nonprofit organizations through expert financial management. As an Accounting Manager/Controller, you'll lead financial planning, reporting, and compliance, ensuring ou...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$280K - $481K *

Join a team that's driving growth in advanced therapeutics through strategic leadership, P&L accountability, and innovative business development. Shape the future of RNA oligonucleotide manufacturing...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$163K - $306K *

Champion the future of laboratory innovation by leading global product strategy, connecting emerging technologies and customer insights to drive impactful business initiatives across diverse markets...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$116K - $219K *

Unlock your potential as a senior contributor in software quality engineering, driving high-quality solutions through collaboration, automation, and Agile practices. Enhance product reliability and ef...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$159K - $319K *

Join a team that's driving innovation in Atomic Spectroscopy sales. Leverage your technical expertise to build relationships and create opportunities across commercial, government, and academic sector...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K *

Join a dynamic team to drive the adoption of innovative vascular therapies, expanding market share through strategic account development and training. This role requires proactive engagement with heal...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.