Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$100K - $120K *

Transform the safety landscape by leading initiatives, mentoring teams, and ensuring compliance across projects. Drive a culture of safety excellence, develop training programs, and collaborate with s...

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Unlock your potential as a Product Manager, driving product health and outcomes through strategic decision-making, collaboration, and customer insights across the product lifecycle. Shape the future o...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $180K *

Unlock potential by leading creative engagements across healthcare accounts. Drive innovative campaigns, mentor teams, and manage client relationships while delivering impactful narratives that resona...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in managing a high-performing Account Management team, driving customer retention and revenue growth through effective strategies and collaboration. Foster team development and optimiz...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $130K *

Join a team that's pivotal in implementing strategic solutions for Fortune 500 clients. You'll drive key project initiatives, ensuring effective change management and superior customer adoption for wo...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$63K - $105K *

Elevate your career as a Junior SAP Integration Developer, driving technical design and development of SAP solutions. Collaborate with stakeholders to ensure seamless system integration and support, w...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$70K - $112K *

Join a team that's redefining clinical research by overseeing complex neurosurgery trials. You'll coordinate innovative studies, ensuring regulatory compliance and quality while collaborating with div...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$66K - $107K *

Join a leading oncology clinical research unit to coordinate innovative trials, ensuring excellence in patient care and regulatory compliance while collaborating with multidisciplinary teams to advanc...

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Join us as a senior leader overseeing financial support for academic units, ensuring exceptional service and compliance. Lead a diverse team, manage budgets, and drive process improvements while colla...

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$67K - $104K *

Collaborate with us to blend clinical speech-language pathology with research, conducting evaluations and therapy for adults with neurogenic disorders while supporting innovative studies in the health...

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$168K - $231K *

Join a team that's dedicated to advancing healthcare technology by designing innovative software solutions for medical devices. Leverage your expertise in embedded systems and Qt development to enhanc...

Today

  •   8 - 10 years exp.  •   Healthcare

$142K - $213K *

Join a team that's shaping the future of project execution in Power Systems. Lead diverse teams, drive operational excellence, and ensure project success across the U.S. while fostering collaboration...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead the charge in managing operations of a dynamic Neuro ICU, ensuring optimal patient care and compliance with established clinical standards while fostering a collaborative team environment...

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$109K - $156K *

Champion reliability by leading SRE projects from inception to production. Collaborate with teams to enhance infrastructure across hybrid environments, driving architectural excellence and operational...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Champion user experience by enhancing our insurance platform's web interface. Collaborate with teams to simplify design, implement UX initiatives, and develop solutions that empower agents and interna...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $155K *

Champion advanced security initiatives by leading Red Team efforts to identify vulnerabilities and enhance protection across enterprise systems through penetration testing and adversarial emulation, w...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $105K *

Champion quality assurance initiatives by resolving production challenges and enhancing manufacturing processes, ensuring customer satisfaction and compliance with industry standards through effective...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$93K - $124K *

Lead the development of compelling cybersecurity narratives and content that connect technology solutions to customer needs. Collaborate across teams to create impactful sales enablement materials and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$68K - $98K *

Transform manufacturing processes by developing custom IT solutions using diverse programming languages and systems. Collaborate with engineers and factory staff to enhance operational efficiency and...

Today

  •   Less than 5 years exp.  •   Transportation

$150K - $180K *

Champion innovative AI platform architecture and drive enterprise-level integration of machine learning, ensuring security, accuracy, and reliability across systems while mentoring teams to elevate te...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$115K - $151K *

Grow your career with a dynamic team focused on AI tool administration and governance. Collaborate across departments to enhance system connectivity and process automation while ensuring data privacy...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $190K *

Lead the charge in combating cyber-enabled fraud by investigating complex threats, analyzing digital signals, and collaborating across teams to enhance detection and risk mitigation strategies...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $150K *

Elevate procurement operations by managing vendor coordination, documentation, and process consistency. This role focuses on execution and queue management, ensuring timely and organized procurement s...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Elevate your career by managing technical programs across global engineering teams. Drive alignment, enhance decision-making, and leverage AI to optimize workflows while supporting senior leadership i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$114K - $171K *

Lead a dynamic team overseeing travel and expense operations, ensuring compliance and efficiency. Drive strategic initiatives, manage vendor relationships, and enhance user experience while optimizing...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.