Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,677
$100K - $120K *
Transform the safety landscape by leading initiatives, mentoring teams, and ensuring compliance across projects. Drive a culture of safety excellence, develop training programs, and collaborate with s...
Reposted today
$95K - $115K *
Unlock your potential as a Product Manager, driving product health and outcomes through strategic decision-making, collaboration, and customer insights across the product lifecycle. Shape the future o...
Today
21GRAMS- Associate Creative Director, Copy
$160K - $180K *
Unlock potential by leading creative engagements across healthcare accounts. Drive innovative campaigns, mentor teams, and manage client relationships while delivering impactful narratives that resona...
Today
$100K - $120K *
Lead the charge in managing a high-performing Account Management team, driving customer retention and revenue growth through effective strategies and collaboration. Foster team development and optimiz...
Today
Senior Implementation Consultant
$100K - $130K *
Join a team that's pivotal in implementing strategic solutions for Fortune 500 clients. You'll drive key project initiatives, ensuring effective change management and superior customer adoption for wo...
Reposted today
Junior SAP Integration Developer
$63K - $105K *
Elevate your career as a Junior SAP Integration Developer, driving technical design and development of SAP solutions. Collaborate with stakeholders to ensure seamless system integration and support, w...
Today
Senior Regulatory Coordinator, Neurosurgery
$70K - $112K *
Join a team that's redefining clinical research by overseeing complex neurosurgery trials. You'll coordinate innovative studies, ensuring regulatory compliance and quality while collaborating with div...
Today
Clinical Research Nurse Coordinator - Duke Cancer Institute
$66K - $107K *
Join a leading oncology clinical research unit to coordinate innovative trials, ensuring excellence in patient care and regulatory compliance while collaborating with multidisciplinary teams to advanc...
Reposted today
Assistant Vice Provost for Business Services
$120K - $150K *
Join us as a senior leader overseeing financial support for academic units, ensuring exceptional service and compliance. Lead a diverse team, manage budgets, and drive process improvements while colla...
Today
$67K - $104K *
Collaborate with us to blend clinical speech-language pathology with research, conducting evaluations and therapy for adults with neurogenic disorders while supporting innovative studies in the health...
Reposted today
Technical Specialist - Embedded QT
$168K - $231K *
Join a team that's dedicated to advancing healthcare technology by designing innovative software solutions for medical devices. Leverage your expertise in embedded systems and Qt development to enhanc...
Today
$142K - $213K *
Join a team that's shaping the future of project execution in Power Systems. Lead diverse teams, drive operational excellence, and ensure project success across the U.S. while fostering collaboration...
Today
Nurse Manager, Operations - Neuro ICU
$88K - $105K *
Lead the charge in managing operations of a dynamic Neuro ICU, ensuring optimal patient care and compliance with established clinical standards while fostering a collaborative team environment...
Reposted today
Staff Site Reliability Engineer
$109K - $156K *
Champion reliability by leading SRE projects from inception to production. Collaborate with teams to enhance infrastructure across hybrid environments, driving architectural excellence and operational...
Today
$95K - $115K *
Champion user experience by enhancing our insurance platform's web interface. Collaborate with teams to simplify design, implement UX initiatives, and develop solutions that empower agents and interna...
Today
Lead Information Security Engineer - Red Team
$105K - $155K *
Champion advanced security initiatives by leading Red Team efforts to identify vulnerabilities and enhance protection across enterprise systems through penetration testing and adversarial emulation, w...
Reposted today
$80K - $105K *
Champion quality assurance initiatives by resolving production challenges and enhancing manufacturing processes, ensuring customer satisfaction and compliance with industry standards through effective...
Reposted today
Lead Solution Marketing Manager, Cybersecurity Segments and Industries
$93K - $124K *
Lead the development of compelling cybersecurity narratives and content that connect technology solutions to customer needs. Collaborate across teams to create impactful sales enablement materials and...
Today
Manufacturing IT Systems & Software Engineer
$68K - $98K *
Transform manufacturing processes by developing custom IT solutions using diverse programming languages and systems. Collaborate with engineers and factory staff to enhance operational efficiency and...
Today
Senior Staff Machine Learning Engineer - US
$150K - $180K *
Champion innovative AI platform architecture and drive enterprise-level integration of machine learning, ensuring security, accuracy, and reliability across systems while mentoring teams to elevate te...
Reposted today
AI Administrator, Business Applications
$115K - $151K *
Grow your career with a dynamic team focused on AI tool administration and governance. Collaborate across departments to enhance system connectivity and process automation while ensuring data privacy...
Today
$120K - $190K *
Lead the charge in combating cyber-enabled fraud by investigating complex threats, analyzing digital signals, and collaborating across teams to enhance detection and risk mitigation strategies...
Today
Procurement Operations Analyst
$115K - $150K *
Elevate procurement operations by managing vendor coordination, documentation, and process consistency. This role focuses on execution and queue management, ensuring timely and organized procurement s...
Today
Software Engineering Program Manager
$120K - $145K *
Elevate your career by managing technical programs across global engineering teams. Drive alignment, enhance decision-making, and leverage AI to optimize workflows while supporting senior leadership i...
Today
Associate Director Travel & Expense
$114K - $171K *
Lead a dynamic team overseeing travel and expense operations, ensuring compliance and efficiency. Drive strategic initiatives, manage vendor relationships, and enhance user experience while optimizing...
Reposted today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.