Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,657
$90K - $110K *
Drive AI transformation by mapping current processes and designing future-state models across G&A functions. Collaborate with stakeholders to identify automation opportunities and enhance operational...
1 week ago
$140K - $185K *
Transform project delivery by managing IT initiatives for California agencies. Collaborate with state staff to ensure timely, budget-compliant outcomes while leveraging Agile methodologies and large s...
1 week ago
Advanced Practice Provider (NP/PA) - SOM Trauma Surgery
$90K - $110K *
Join a team that's dedicated to delivering high-quality, cost-effective patient care. As a key member of the healthcare team, you'll assess, diagnose, and implement treatment plans while collaborating...
1 week ago
$74K - $107K *
Drive comprehensive patient care as an RN Care Manager, coordinating assessments, care plans, and transitions in a collaborative environment to enhance patient outcomes and support their healthcare jo...
1 week ago
RN Clinical Nurse II-Intermediate Neurosciences & ENT Unit Nights
$71K - $100K *
Tackle complex patient care in a collaborative environment, providing expert nursing services in a new Intermediate Neurosciences and ENT Unit. Engage in patient assessment, education, and leadership...
1 week ago
Outpatient Obstetrics & Gynecology Physician (MD/DO) - UNC Health Southeastern
$210K - $250K *
Advance your career as an OB/GYN physician in a collaborative, team-oriented practice. Enjoy a supportive environment with a 4.5-day workweek, dedicated OR time, and opportunities for teaching and pro...
1 week ago
Family Medicine Advanced Practice Provider (NP/PA) - Eastern NC Medical Group
$90K - $110K *
Advance your career by providing compassionate primary care in a dynamic clinic. Collaborate with a dedicated team to deliver personalized healthcare services to diverse patients, ensuring quality and...
1 week ago
Senior Environmental Resources Manager
$110K - $130K *
Partner with us to lead complex environmental programs, drive hydropower licensing, and foster stakeholder relationships. Utilize your expertise to navigate regulatory landscapes and support strategic...
1 week ago
Global Meetings & Events Manager, Meeting Planning
$95K - $129K *
Champion complex, high-visibility programs from planning to execution. Lead cross-functional teams, manage budgets, and ensure compliance while enhancing attendee experiences in a dynamic corporate en...
1 week ago
Manager, Global Financial Reporting
$143K - $169K *
Shape the future of financial integrity by enhancing our reporting processes and ensuring compliance. Collaborate across functions to deliver accurate financial statements while fostering a robust, sc...
Reposted 1 week ago
$80K - $95K *
Champion strategic HR initiatives by partnering with leaders to enhance talent management, employee relations, and organizational effectiveness, ensuring alignment with business goals and compliance a...
1 week ago
$120K - $192K *
Join a team that's shaping innovative web solutions as a Development Lead. Drive full-stack delivery while mentoring engineers in a dynamic Agile environment, fostering a culture of ownership and cont...
1 week ago
$139K - $208K *
Accelerate progress at a leading procurement organization by driving transformation, managing category strategies, and optimizing supplier performance. Collaborate across teams to deliver measurable v...
Reposted 1 week ago
Purchasing - Purchasing Manager
$80K - $95K *
Empower a dynamic team to enhance procurement processes, ensuring timely delivery of materials and services for construction projects while driving operational excellence and collaboration across depa...
1 week ago
$88K - $120K *
Lead pharmacy operations by ensuring compliance, enhancing patient care, and supervising staff. Drive departmental success through strategic execution, customer service excellence, and adherence to re...
1 week ago
Channel Manager, SAP Solutions & Partner Growth
$148K - $242K *
Drive growth by identifying and developing SAP solutions, working with sales teams and partners to create revenue opportunities and implement strategic sales initiatives across various customer segmen...
Reposted 1 week ago
$160K - $180K *
Unlock your potential as a Technical Recruiter, driving Engineering hiring and building strong talent pipelines. Collaborate with leaders to define roles, enhance candidate experience, and adapt strat...
Reposted 1 week ago
Senior Software Engineer, Query
$185K - $255K *
Elevate data management by designing scalable storage solutions and ingestion pipelines. Lead technical direction, optimize performance, and ensure reliable access to historical data for product teams...
1 week ago
Urgent Care Nurse Practitioner / Physician Assistant - Wallace, NC | Up to $10K Sign-On Bonus
$114K - $187K *
Unlock potential by providing high-quality urgent care as a Family Nurse Practitioner or Physician Assistant. Enjoy a flexible schedule, competitive pay, and a supportive team environment while making...
1 week ago
Software Engineer III, iOS - Cal AI
$135K - $165K *
Engage with our Cal AI team to enhance user experiences through innovative iOS development. Collaborate, mentor, and implement high-quality features that empower users on their health journeys while f...
1 week ago
$164K - $205K *
Elevate scientific rigor in real-world evidence development. Collaborate with cross-functional teams to ensure agent conceptualization and evaluation meet scientific standards, driving impactful solut...
1 week ago
Remote Operations Specialist - Advanced
$69K - $124K *
Join a team that's dedicated to enhancing project success through effective coordination and support. As an Operations Specialist, you'll facilitate the Services Engagement Lifecycle, ensuring seamles...
1 week ago
$85K - $110K *
Engage top talent as a full-cycle Talent Acquisition Partner, managing recruitment across diverse functions and levels. Collaborate with hiring managers to attract and hire skilled professionals, ensu...
1 week ago
Director Manager CRM Klaviyo Email Marketing Lifecycle Loyalty
$140K - $170K *
Champion the future of customer engagement by leading lifecycle marketing strategies. Drive retention and loyalty through data-driven personalization across multiple channels, maximizing customer life...
1 week ago
Sr. Underwriter - Life Underwriting - Remote
$87K - $146K *
Partner with us to deliver thoughtful underwriting decisions and build trusted relationships. Leverage your expertise to enhance processes and contribute to a collaborative environment that drives inn...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.