Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,816

Sort By: Relevance

$160K - $200K *

Lead IT's AI-first transformation by driving vision, coordinating cross-functional initiatives, and ensuring platform uptime while empowering teams to adopt AI tools effectively across the organizatio...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in executing North America's largest trade shows and events. Collaborate with sales and marketing teams to drive strategy, manage budgets, and enhance brand presence, while ensuring al...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$134K - $185K *

Reimagine paid search strategy and execution, leading a dynamic team to enhance performance, drive growth, and establish market presence while connecting client objectives with innovative solutions an...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Elevate your career by driving LPG tank sales across the Eastern US. Build lasting relationships with propane marketers and distributors while executing a results-driven commercial strategy to achieve...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$105K - $130K *

Elevate patient care by managing clinical support for monitoring systems. Lead diverse teams to enhance customer relationships and ensure effective product utilization post-implementation, driving cli...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$90K *

Deliver exceptional medical sales solutions by building relationships with healthcare professionals, demonstrating products, and exceeding sales goals while ensuring customer satisfaction and effectiv...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$113K - $188K *

Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in building operations and maintenance, ensuring exceptional tenant satisfaction and safety. Oversee engineering teams, manage budgets, and drive efficiency while nurturing talent and...

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Lead the charge in transforming data analytics for critical enterprise systems. Drive innovative solutions, manage complex data architectures, and collaborate with diverse teams to enhance data-driven...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate partner success by managing strategic mid-market and enterprise relationships. Drive revenue growth through effective onboarding, enablement, and co-selling, while collaborating cross-function...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic finance team as you oversee financial reporting, manage reconciliations, and enhance accounting processes. Your expertise will ensure compliance with GAAP while supporting audits and op...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$500K+*

Champion the future of neuroradiology by providing expert diagnostic services in a collaborative, supportive environment. Engage with a dedicated team to deliver high-quality care across multiple faci...

Greensboro, NCRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$140K - $178K *

Lead the charge in architecting and optimizing enterprise AI infrastructure, collaborating with global teams to enhance performance and reliability of cutting-edge supercomputing platforms while mento...

Yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$160K - $180K *

Join a team that's dedicated to delivering seamless technical solutions for clients. You'll scope, implement, and maintain risk screening and data integration workflows, ensuring optimal performance a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$103K - $146K *

Drive proactive, data-driven security by owning data pipelines and attribution layers. Transform raw security data into actionable insights, enhancing remediation speed and influencing AI-augmented an...

North Carolina, USRemote

Yesterday

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$103K - $146K *

Unlock potential by becoming the Domain Expert for data pipelines, transforming security data into actionable insights. Drive proactive monitoring and enhance data quality to reduce remediation time a...

Yesterday

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$110K - $115K *

Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$240K - $318K *

Lead a global BSS engineering team, driving architecture, delivery, and product strategy while ensuring platform performance and compliance across diverse telecommunications solutions...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Optimize supply planning for finished goods, driving process improvements and inventory management while collaborating with cross-functional teams to meet sales and operational goals...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Join a dynamic team to drive customer activation and retention strategies across the prescription lifecycle. Collaborate cross-functionally to optimize customer journeys and deliver measurable growth...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$70K - $117K *

Transform facilities assessment by leveraging your expertise in mechanical systems. Collaborate with a dynamic team to evaluate diverse infrastructures, ensuring compliance and operational excellence...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$123K - $188K *

Elevate channel partnerships by driving service growth and collaboration. Leverage your expertise in sales and services to implement strategies that enhance revenue and foster relationships with busin...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$107K - $167K *

Manage complex, cross-functional projects to enhance Product Lifecycle processes, ensuring disciplined execution and stakeholder collaboration for successful product development improvements across th...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $265K *

Drive the development of seamless integrations for security platforms, leading a team to deliver high-quality, reliable products that enhance customer security stacks and ensure compatibility with evo...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$115K - $162K *

Develop and optimize backend features for a Rust-based graph data service, enhancing reliability and scalability while collaborating across teams to deliver impactful solutions for GitLab's platform...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.