Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,632
$100K - $120K *
Lead the charge in managing a high-performing Account Management team, driving customer retention and revenue growth through effective strategies and collaboration. Foster team development and optimiz...
3 days ago
Senior Regulatory Coordinator, Neurosurgery
$70K - $112K *
Join a team that's redefining clinical research by overseeing complex neurosurgery trials. You'll coordinate innovative studies, ensuring regulatory compliance and quality while collaborating with div...
3 days ago
Clinical Research Nurse Coordinator - Duke Cancer Institute
$66K - $107K *
Join a leading oncology clinical research unit to coordinate innovative trials, ensuring excellence in patient care and regulatory compliance while collaborating with multidisciplinary teams to advanc...
Reposted 3 days ago
Assistant Vice Provost for Business Services
$120K - $150K *
Join us as a senior leader overseeing financial support for academic units, ensuring exceptional service and compliance. Lead a diverse team, manage budgets, and drive process improvements while colla...
3 days ago
$67K - $104K *
Collaborate with us to blend clinical speech-language pathology with research, conducting evaluations and therapy for adults with neurogenic disorders while supporting innovative studies in the health...
Reposted 3 days ago
$142K - $213K *
Join a team that's shaping the future of project execution in Power Systems. Lead diverse teams, drive operational excellence, and ensure project success across the U.S. while fostering collaboration...
3 days ago
Staff Site Reliability Engineer
$109K - $156K *
Champion reliability by leading SRE projects from inception to production. Collaborate with teams to enhance infrastructure across hybrid environments, driving architectural excellence and operational...
3 days ago
$95K - $115K *
Champion user experience by enhancing our insurance platform's web interface. Collaborate with teams to simplify design, implement UX initiatives, and develop solutions that empower agents and interna...
3 days ago
Lead Information Security Engineer - Red Team
$105K - $155K *
Champion advanced security initiatives by leading Red Team efforts to identify vulnerabilities and enhance protection across enterprise systems through penetration testing and adversarial emulation, w...
Reposted 3 days ago
$80K - $105K *
Champion quality assurance initiatives by resolving production challenges and enhancing manufacturing processes, ensuring customer satisfaction and compliance with industry standards through effective...
Reposted 3 days ago
Lead Solution Marketing Manager, Cybersecurity Segments and Industries
$93K - $124K *
Lead the development of compelling cybersecurity narratives and content that connect technology solutions to customer needs. Collaborate across teams to create impactful sales enablement materials and...
3 days ago
Senior Staff Machine Learning Engineer - US
$150K - $180K *
Champion innovative AI platform architecture and drive enterprise-level integration of machine learning, ensuring security, accuracy, and reliability across systems while mentoring teams to elevate te...
Reposted 3 days ago
AI Administrator, Business Applications
$115K - $151K *
Grow your career with a dynamic team focused on AI tool administration and governance. Collaborate across departments to enhance system connectivity and process automation while ensuring data privacy...
3 days ago
$120K - $190K *
Lead the charge in combating cyber-enabled fraud by investigating complex threats, analyzing digital signals, and collaborating across teams to enhance detection and risk mitigation strategies...
3 days ago
Procurement Operations Analyst
$115K - $150K *
Elevate procurement operations by managing vendor coordination, documentation, and process consistency. This role focuses on execution and queue management, ensuring timely and organized procurement s...
3 days ago
Software Engineering Program Manager
$120K - $145K *
Elevate your career by managing technical programs across global engineering teams. Drive alignment, enhance decision-making, and leverage AI to optimize workflows while supporting senior leadership i...
3 days ago
$95K - $155K *
Lead the charge in municipal engineering projects, collaborating with multidisciplinary teams to design and implement innovative water, wastewater, and roadway systems while ensuring client satisfacti...
3 days ago
Developer - Salesforce Process Engineering
$120K - $150K *
Optimize our Salesforce environment by developing innovative solutions and collaborating with cross-functional teams to enhance platform performance and user experience in a dynamic IT Process Enginee...
3 days ago
Project Executive, Grocery & Retail Construction Programs
$130K - $160K *
Join a team that's transforming retail spaces by leading multi-site construction programs. You'll partner with senior stakeholders to drive strategic initiatives, ensuring successful execution and fin...
3 days ago
$108K - $140K *
Transform talent acquisition by leading a dynamic recruiting team, driving data-informed strategies, and enhancing candidate experiences to meet organizational growth and workforce needs...
3 days ago
Marketing Technology Product Owner - Salesforce Loyalty & Offer Management
$91K - $145K *
Optimize customer engagement as a Product Owner, driving innovation in Salesforce Loyalty Management. Partner with cross-functional teams to enhance product value and enhance user experiences through...
Reposted 3 days ago
$80K - $95K *
Drive innovation in healthcare technology management by serving as a key advisor in biomedical engineering, overseeing medical technology infrastructure, and ensuring seamless integration of clinical...
3 days ago
Director, Enterprise Enablement
$150K - $180K *
Drive transformative AI initiatives across departments by leading a strategic team in designing scalable, agentic workflows that enhance decision-making and efficiency, ensuring measurable business ou...
Reposted 3 days ago
Specialist Seller, Enterprise Core (Tracking Label)
$222K - $278K *
Empower businesses by eliminating supply chain blind spots. Drive adoption of our innovative Tracking Label product, collaborating with Enterprise teams to enhance shipment visibility and security acr...
3 days ago
$160K - $200K *
Drive the evolution of Sales Operations by designing and optimizing processes, governance, and technology to enhance execution and productivity across the organization, ensuring alignment with strateg...
3 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.