Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$175K - $195K *

Shape the future of enterprise AI solutions by leading technical delivery and client engagement. Utilize your expertise in AI platforms to create measurable outcomes and drive adoption, while collabor...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead enterprise implementation initiatives for Levelpath and JAGGAER, focusing on system configuration, workflow design, and API integrations. Collaborate with stakeholders to deliver secure, scalable...

3 days ago

  •   8 - 10 years exp.  •   Staffing

$143K *

Join a team that's redefining virtual healthcare by delivering high-quality, patient-centered care. As a key member, you'll provide comprehensive virtual medical services, collaborate with stakeholder...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform your career by leading financial strategy and operations at a dynamic institution. Drive sustainable growth, oversee budgeting and compliance, and collaborate with executive leadership to en...

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$200K - $250K *

Transform your career by driving new business growth for SMBs through innovative cloud, backup, and disaster recovery solutions. Own your pipeline and strategy while collaborating with a dedicated tea...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Elevate your career by contributing to innovative civil engineering designs while supporting project management and team collaboration to ensure successful project delivery and client satisfaction...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$132K - $154K *

Elevate customer engagement by leading strategic initiatives in the insurance sector. As a trusted advisor, you'll bridge client needs with platform capabilities, driving revenue and enhancing Solutio...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$187K - $257K *

Empower transformation initiatives by leading enterprise projects, managing stakeholder relationships, and driving strategic outcomes. Collaborate with diverse teams to define program strategies and e...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $185K *

Lead and inspire engineering teams to deliver high-quality digital products, ensuring alignment with business priorities while fostering a culture of collaboration and continuous improvement in a dyna...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $190K *

Pioneer the growth of a $20M+ regional field service business, driving strategy, profitability, and team development while ensuring safety and quality in service delivery. Collaborate with cross-funct...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$287K - $359K *

Drive growth as you cultivate federal accounts, enhance sales strategies, and facilitate large, strategic deals. Leverage your expertise to position mission-critical solutions in a competitive landsca...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform manufacturing processes by optimizing production and driving innovation. Collaborate with cross-functional teams to enhance quality and efficiency while ensuring compliance with safety stand...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $135K *

Drive the evolution of critical DNS infrastructure, ensuring operational excellence, collaborating across teams, and enhancing production services through automation and API development...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Drive operational excellence by leading integrated planning and scheduling across multiple facilities. Collaborate with cross-functional teams to optimize inventory management, enhance service deliver...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$134K - $215K *

Empower our team by leading operational solutions and client services. Drive strategic initiatives, enhance product delivery, and ensure exceptional quality across digital platforms while collaboratin...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Drive feasibility strategy and execution for clinical studies, ensuring alignment with program objectives. Collaborate with cross-functional teams to deliver insights and recommendations that enhance...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in optimizing client waste and recycling programs, ensuring savings and compliance while managing supplier relationships and client interactions. Drive strategic improvements and enhan...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$117K - $195K *

Drive impactful data analysis and visualization for a key Federal client, leveraging big data techniques and statistical methods to deliver actionable insights and solutions. Collaborate with a dynami...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive impactful in-store communication strategies that enhance customer experience and align with brand objectives. Lead a team to innovate signage solutions, manage print services, and collaborate ac...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$88K - $105K *

Deliver application support for GxP systems in a regulated environment, managing upgrades, troubleshooting, and ensuring compliance while collaborating with vendors and internal teams to enhance syste...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$117K - $196K *

Optimize the lending domain by designing and maintaining ontologies and semantic models. Collaborate with stakeholders to enhance data integration and support AI initiatives, ensuring alignment with e...

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$160K - $215K *

Empower innovation by designing and prototyping product experiences, collaborating closely with cross-functional teams to enhance user workflows and drive product evolution from concept to execution...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Drive retail excellence by managing AI-driven merchandising programs that enhance product placement and sales growth across key categories. Collaborate with teams to transform insights into actionable...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Join a leading role in driving HR strategies and initiatives to enhance teammate engagement and operational excellence, promoting a safe and compliant workplace, while evolving HR practices within a f...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.