Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,788
Principal Sales Account Manager - USAF
$317K - $371K *
Deliver innovative solutions in defense sales, expanding Air Force accounts while leveraging extensive industry knowledge and strategic relationships to meet client needs and drive revenue growth...
Reposted today
Strategic Program Manager - Boston
$123K - $145K *
Optimize product launches by collaborating cross-functionally to ensure timely delivery and high quality. Leverage engineering expertise to manage complex programs, drive continuous improvement, and e...
Today
Digital Sales Manager - Remote
$116K - $149K *
Manage strategic growth initiatives for digital solutions in commercial markets. Collaborate with cross-functional teams to drive customer adoption, enhance operational performance, and achieve revenu...
Today
Identity Operations Service Lead
$162K - $292K *
Join a team that's redefining identity operations by leading a 24/7 team to enhance access management strategies. You'll shape the vision, drive process innovation, and foster talent in a collaborativ...
Reposted today
Sr. Director, Revenue Operations - AMER
$198K - $298K *
Lead the charge in shaping the AMER Revenue Operations strategy, driving operational excellence and predictable outcomes. Collaborate with executive leadership to optimize sales processes and build a...
Today
$95K - $115K *
Join us to facilitate software design, coding, and testing while enhancing system reliability. Collaborate with cross-functional teams to deliver high-quality solutions and support user training for s...
Today
$160K - $220K *
Champion the design and architecture of data systems, driving innovation and collaboration across teams to enhance user experiences and optimize data management for MyFitnessPal's ecosystem...
Today
Software Engineer, Red Platform
$97K - $120K *
Champion the development of innovative software solutions, collaborating with cross-functional teams to design, implement, and optimize applications that drive business success while mentoring junior...
Today
Strategic Client Consultant I - National Accounts
$80K - $95K *
Transform client relationships by driving retention and growth through strategic insights and data analysis. Lead negotiations with complex clients, ensuring profitable partnerships while collaboratin...
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Senior Customer Success Manager
$110K - $130K *
Transform customer experiences by driving satisfaction and growth through strategic partnerships. Leverage your L&D expertise to enhance client engagement and ensure program success while collaboratin...
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Partner Engagement and Communications Manager
$85K - $110K *
Elevate your career by leading impactful fundraising communications and events. Drive donor engagement through compelling storytelling and strategic initiatives while managing a diverse portfolio in a...
Today
$180K - $200K *
Transform our data landscape by leading the end-to-end data platform, modernizing architecture, and empowering analytics teams to deliver trusted insights across the organization. Drive innovation wit...
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$130K - $160K *
Transform the user experience and operational workflows in a complex two-sided marketplace. Lead product initiatives that enhance clinician and district interactions, streamline processes, and drive i...
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Director, Quality Assurance (Clinical)
$175K - $236K *
Champion quality excellence by leading a dynamic team to enhance compliance and drive continuous improvement in clinical development. Collaborate across functions to ensure regulatory readiness and de...
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Senior Managing Counsel-Pharmacy Network Operations
$197K - $328K *
Shape the future of pharmacy network operations by leading a team of attorneys, providing strategic legal counsel on regulatory, operational, and transactional matters within the PBM landscape, while...
Reposted today
$148K - $208K *
Optimize business planning and financial analysis for Americas Sales, driving strategic insights and operational excellence through advanced modeling, reporting, and AI-enabled process improvements to...
Reposted today
Senior Campus Marketing Manager
$110K - $150K *
Transform student engagement by developing impactful marketing campaigns and community initiatives across partner campuses. Drive enrollment and retention through strategic partnerships, innovative ou...
Today
Director, GLP-1 & Cardiometabolic Product Marketing
$194K - $242K *
Unlock potential by leading product marketing strategies in GLP-1 and cardiometabolic health. Collaborate with cross-functional teams to enhance buyer clarity and sales effectiveness, while coaching a...
Today
Director Aseptic Compliance, Training Materials & Batch Release
$125K - $150K *
Empower aseptic manufacturing excellence by leading training initiatives, ensuring compliance, and driving continuous improvement. Collaborate across teams to enhance aseptic practices and maintain hi...
Today
Director of Cloud Architecture & Platform Engineering (Remote)
$150K - $180K *
Lead cloud architecture and platform engineering, balancing strategic vision with hands-on technical execution. Drive team growth, ensure compliance, and enhance infrastructure for secure healthcare s...
Today
$125K - $150K *
Join us to drive growth in enterprise accounts, owning the full sales cycle from prospecting to closing. Collaborate with a dynamic team to convert leads into revenue while leveraging market insights...
Today
Strategic Account Executive, Financial Services - US East
$114K - $186K *
Drive strategic enterprise growth by guiding large organizations through their DevSecOps transformation, ensuring successful adoption and long-term value from GitLab's AI-powered platform while managi...
Today
Physician (Family or Internal Medicine MD/DO)
$168K - $226K *
Empower healthcare delivery by providing comprehensive primary care services, managing diverse patient needs, and engaging in quality improvement initiatives while ensuring optimal patient outcomes an...
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$140K - $170K *
Join a dynamic team to optimize operational systems, drive growth, and enhance performance across departments. Collaborate with leadership to ensure strategic goals translate into measurable results a...
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Principal SAP Plant Maintenance Consultant
$150K - $180K *
Engage in designing and implementing SAP Plant Maintenance solutions for complex federal projects. Collaborate with stakeholders to enhance asset management efficiency and ensure seamless integration...
Today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.