Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
$220K - $287K *
Manage construction projects by planning, organizing, and supervising teams to ensure quality, compliance, and budget adherence while driving operational excellence and safety standards...
Yesterday
Software Engineer Senior Consultant II
$90K - $153K *
Drive the design and development of enterprise applications as a Senior Software Engineer, leading full stack solutions in a collaborative Agile environment. Partner with cross-functional teams to tac...
Yesterday
Cybersecurity Regional Manager
$134K - $241K *
Elevate your career by leading cybersecurity initiatives across California and the West Coast. Drive customer engagement, enhance security compliance, and support critical infrastructure sectors while...
Yesterday
Senior Marketing Campaigns Manager
$145K - $185K *
Transform account-based marketing strategies into impactful campaigns that drive pipeline growth and revenue. Lead integrated initiatives across multiple channels, ensuring alignment with sales and ma...
Reposted yesterday
Senior Manager, Enterprise Data Products
$120K - $145K *
Champion data innovation by leading a team to enhance enterprise data quality, governance, and analytics. Drive strategic initiatives and collaborate with cross-functional teams to align data products...
Yesterday
Pulmonologist (MD/DO) - Onslow Memorial Hospital
$210K - $250K *
Lead the charge in providing comprehensive care for chronic respiratory diseases, utilizing your expertise in pulmonology to enhance patient outcomes and manage complex cases effectively...
Yesterday
$88K - $105K *
Drive your career forward by leading SEO strategy and optimization efforts. Collaborate across teams to enhance digital visibility, user engagement, and business performance through data-driven insigh...
Yesterday
Senior Manager, Enterprise Data Products
$120K - $145K *
Transform enterprise data management by leading a team to enhance data quality, governance, and analytics. Drive strategic initiatives and collaborate with cross-functional teams to deliver scalable d...
Yesterday
Director, QMS Process Owner - Global Change Control Management
$168K - $228K *
Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...
Yesterday
Associate Director, Global Commercial Trade Compliance
$138K - $188K *
Lead global trade compliance initiatives, ensuring adherence to regulations across multiple jurisdictions. Drive strategic programs for import/export operations, risk management, and partner governanc...
Yesterday
Nurse Practitioner-Hematology Oncology
$95K - $115K *
Elevate patient care by independently managing acute and chronic conditions, collaborating with interdisciplinary teams, and implementing evidence-based practices to enhance health outcomes in a dynam...
Yesterday
Physician (Hematology Oncology)
$210K - $250K *
Join a team that's dedicated to providing expert consultation in Hematology and Oncology, managing patient care in both inpatient and outpatient settings while guiding advanced practice providers and...
Yesterday
$80K - $95K *
Advance the future of mental health by providing expert psychological assessments, evaluations, and treatments. Collaborate with interdisciplinary teams to enhance patient care and manage complex clin...
Yesterday
$110K - $130K *
Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...
Yesterday
HSE and Portfolio Performance Lead
$110K - $130K *
Lead the charge in enhancing health, safety, and environmental performance across data center construction projects. Collaborate with teams to ensure compliance with OSHA standards and drive continuou...
Yesterday
Senior Scientist I Team Leader
$110K - $130K *
Pioneer innovative crop genetic engineering by leading a team of scientists in transgenic event generation, enhancing biotech capabilities, and driving efficient product development in a dynamic resea...
Yesterday
$110K - $130K *
Innovate in cancer research by designing and deploying advanced AI and machine learning solutions. Collaborate with cross-functional teams to develop multimodal models integrating diverse clinical dat...
Yesterday
Field Reimbursement Manager, Southeast - Skeletal Dysplasia,
$185K - $235K *
Optimize family access and reimbursement strategies in a hybrid role, collaborating with healthcare providers and families. Leverage your expertise to navigate complex pathways, ensuring compliance an...
Yesterday
Product Manager- Data Acceleration
$120K - $145K *
Join a dynamic team to drive product strategy for high-performance data processing and analytics, shaping modern solutions that integrate seamlessly with cloud-native environments and enhancing the wa...
Reposted yesterday
Product Manager- Data Acceleration
$120K - $145K *
Transform product strategy for high-performance data processing. Collaborate with cross-functional teams to drive innovation in cloud-native environments, ensuring seamless integration and exceptional...
Reposted yesterday
Field Reimbursement Manager, Midwest - Skeletal Dysplasia
$185K - $235K *
Join a team that's redefining access in healthcare by leading reimbursement strategies and supporting families in navigating complex pathways for Skeletal Dysplasia therapies. Drive impactful change t...
Yesterday
Identity and Access Management Engineering Technology Director
$215K - $355K *
Develop and lead advanced IAM engineering initiatives for multi-cloud environments. Shape the organization's cloud-agnostic identity strategy while fostering teams focused on innovation, security, and...
Reposted yesterday
Comm Appraisal Services Conslt.
$80K - $95K *
Lead the charge in delivering expert appraisal services for commercial real estate, ensuring compliance and quality through vendor management, training, and performance evaluation while collaborating...
Yesterday
Senior Product Marketing Manager (US)
$120K - $145K *
Unlock potential by leading product marketing strategies for developer-facing solutions. Collaborate across teams to enhance messaging, drive customer engagement, and ensure successful deployments, al...
Yesterday
$95K - $125K *
Transform client relations through innovative sales strategies while achieving consistent targets in a dynamic market. Drive growth by effectively managing existing partnerships and exploring new oppo...
Reposted yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.