Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$300K *
Unlock potential by leading national consultant relations, driving strategy, and managing a team to enhance employer opportunities. Engage with key consulting firms while fostering relationships that...
Yesterday
$100K *
Analyze market trends and manage high-performing sales teams to enhance revenue. Contribute to strategic initiatives aimed at driving sales growth while fostering a competitive and productive team cul...
Reposted yesterday
Content Management and Operations Lead (Drupal)
$110K - $155K *
Lead content operations for a federal web services program, managing a team to ensure timely, accurate, and accessible communication. Drive strategic planning, oversee Drupal content management, and e...
Reposted yesterday
$135K - $175K *
Unlock potential by driving advanced network solutions, providing technical leadership, and optimizing architecture for high performance and security in a global enterprise environment...
Reposted yesterday
$90K - $110K *
Champion growth by expanding dealership networks and driving financing adoption in the powersports industry. Build relationships, identify opportunities, and enhance dealer experiences through strateg...
Yesterday
$130K - $155K *
Transform data into actionable insights by leading research initiatives, collaborating with business leaders, and developing predictive models to drive strategic decisions and enhance product offering...
Yesterday
Forward Deployed Consultant, Manufacturing
$125K - $150K *
Drive AI transformations in manufacturing by collaborating with C-level executives to identify high-impact opportunities, build tailored solutions, and achieve measurable results in core operating pro...
Reposted yesterday
Senior Risk Manager - Investment Advisory
$110K - $130K *
Join a team that's dedicated to managing investment advisory risks, collaborating across the organization to enhance risk management initiatives and support the Enterprise Risk Management framework. D...
Reposted yesterday
Manager, Bulk Distribution Services
$95K - $165K *
Lead the charge in optimizing bulk distribution services, managing barge supply chains, and ensuring operational excellence from stockpile management to delivery. Collaborate cross-functionally to enh...
Reposted yesterday
Business Operations & Program Management Support Analyst - Senior
$140K - $175K *
Unlock strategic program management oversight by analyzing cross-program activities, mitigating risks, and ensuring effective communication of technical progress to stakeholders. Drive mission outcome...
Reposted yesterday
$125K - $150K *
Empower customer success by designing impactful journeys that drive retention and revenue. Lead cross-functional teams to create and optimize service blueprints, ensuring seamless customer experiences...
Yesterday
Taxpayer Advocate Group Manager
$80K - $95K *
Transform taxpayer advocacy by leading a dedicated team to resolve complex cases, ensuring timely solutions and alignment with national priorities while fostering collaboration across IRS divisions...
Yesterday
Staff Data Scientist - Ads Marketplace
$190K - $283K *
Drive impactful data analyses and innovative experiment design to enhance product strategies and optimize Ads Marketplace performance, collaborating with cross-functional teams in a flexible, hybrid w...
Reposted yesterday
Finance Manager, Adaptive Planning
$110K - $130K *
Lead the charge in optimizing our Adaptive Planning platform, ensuring accurate data management and seamless integrations. Collaborate with cross-functional teams to enhance reporting and streamline f...
Yesterday
Senior Account Manager, Paid Media (Omnichannel)
$75K - $95K *
Elevate mobile app acquisition strategies by managing omni-channel paid media campaigns. Collaborate with clients to optimize performance, drive growth, and ensure seamless execution across platforms...
Yesterday
$90K - $92K *
Join a dynamic team as you support project execution and management for USACE maintenance tasks. Collaborate with stakeholders, track performance metrics, and guide project teams to ensure successful...
Yesterday
Vice President, Deputy General Counsel, Product, Regulatory & Litigation
$370K - $415K *
Unlock potential by leading Affirm's global legal strategy across Product, Regulatory, and Litigation teams. Collaborate with executives to drive innovation while managing complex legal risks in the c...
Yesterday
$83K - $140K *
Innovate financial strategies by partnering with R&D leaders to optimize costs, enhance reporting frameworks, and drive accurate forecasting in a dynamic environment. Your analytical skills will shape...
Yesterday
Senior Medical Science Liaison - Bone Health - MO, AR, KS
$172K - $233K *
Engage with healthcare leaders to advance scientific communication in bone health. This role involves collaboration, mentorship, and strategic support to enhance patient care and drive research initia...
2 days ago
$95K - $115K *
Shape the future of our organic social media presence by managing channels, coordinating campaigns, and leveraging analytics to enhance engagement and community growth across multiple platforms...
2 days ago
$85K - $118K *
Empower patient care by delivering dialysis treatments and collaborating with a dedicated team. Utilize your critical thinking skills in a fast-paced environment to ensure the safety and wellbeing of...
2 days ago
Altium Designer Trainer and Content Creator
$118K - $141K *
Deliver engaging training and develop content for Altium Designer, leveraging your PCB design expertise. Collaborate with teams to enhance training quality and support customer adoption through effect...
2 days ago
Senior Software Engineer, Operations Tools & Al Enablement
$120K - $145K *
Join a dynamic team to enhance Robotics Operations through innovative software solutions. Collaborate with cross-functional teams to identify needs, deliver impactful improvements, and maintain reliab...
2 days ago
$125K - $145K *
Lead and optimize transportation operations, driving excellence through team development, P&L management, and strategic partnerships. Foster a safety-first culture while exceeding customer expectation...
2 days ago
Commercial Project Manager, Pharmaceuticals
$80K - $95K *
Shape customer success by managing project timelines and expectations, fostering relationships, and ensuring accurate forecasting and billing. Drive operational excellence and continuous improvement t...
Reposted 2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.