Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Software Engineer - Vehicle Health Management
$160K - $217K *
Advance critical software solutions for embedded systems, ensuring performance and compliance across military applications with a focus on lifecycle management and predictive maintenance. Join a dynam...
Reposted 1 week ago
$105K - $128K *
Champion the development of cutting-edge weapon planning software, collaborating with cross-functional teams to enhance mission-critical systems using Agile methodologies and modern technologies like...
1 week ago
Procurement Agent (Procurement Admin)
$110K - $136K *
Innovate procurement strategies by integrating program objectives into sourcing, enhancing supplier relationships, and driving competitive contract negotiations to ensure optimal performance and compl...
Reposted 1 week ago
In-Home Health - Nurse Practitioner or Physician Assistant (Full Time) - Onondaga, NY
$95K - $206K *
Advance health outcomes by providing in-home evaluations, fostering trust and personalized care. Engage with patients to bridge gaps in health services, ensuring comprehensive support tailored to indi...
1 week ago
Staff Pharmacist FT- 7 on, 7 off
$124K - $158K *
Help us enhance patient care by managing pharmacy operations, ensuring compliance, and leading a dedicated team. Your expertise will drive safe dispensing, patient counseling, and immunization service...
1 week ago
$124K - $157K *
Lead the charge in transforming patient care by managing pharmacy operations, ensuring compliance, and fostering a culture of excellence while delivering compassionate service and support to the pharm...
1 week ago
Application Development Team Manager
$147K - $198K *
Lead a dynamic software development team, driving modernization and secure engineering practices across legacy and cloud-native systems while fostering collaboration and high-quality delivery...
1 week ago
Dashboard Developer (Medicare/Medicaid)
$72K - $97K *
Drive impactful data visualization by designing and maintaining interactive dashboards. Collaborate with analysts to convert complex data into actionable insights, enhancing decision-making for Medica...
1 week ago
Sr. Healthcare Data Analyst (Medicaid)
$112K - $143K *
Join a team that's dedicated to transforming healthcare data into actionable insights. Leverage your expertise in data analytics to support critical missions, enhance program oversight, and drive solu...
1 week ago
ICAM Data Engineer – IGA Analytics & Reporting
$127K - $172K *
Unlock your potential by designing and optimizing Power BI reporting solutions that transform complex identity datasets into actionable insights, enhancing enterprise decision-making and compliance re...
1 week ago
$119K - $161K *
Transform web applications by developing, deploying, and maintaining PHP solutions. Collaborate with cross-functional teams to enhance user experience and ensure optimal functionality in a client-faci...
1 week ago
Senior Director - Business Finance
$206K - $268K *
Empower operational finance by leading cost-of-revenue functions, serving as a strategic partner to executives and enhancing organizational performance and scalability through effective leadership and...
Reposted 1 week ago
Director of Sales, North Central
$150K - $180K *
Champion our enterprise sales growth by leading and developing a high-performing team across the North Central U.S., driving strategy, accountability, and client engagement to close high-value deals a...
Reposted 1 week ago
$80K - $95K *
Lead the charge in enhancing equipment reliability and team performance in a fast-paced manufacturing environment. Drive continuous improvement initiatives while fostering a culture of safety and acco...
1 week ago
Mercedes-Benz Automotive Finance Manager
$150K - $350K *
Join a team that's dedicated to providing exceptional finance solutions in a fast-paced automotive environment. Leverage your expertise to finalize deals, maintain compliance, and build strong relatio...
1 week ago
$120K - $150K *
Empower our Digital team as a Senior Software Engineer, driving full stack development and modernization initiatives. Collaborate closely to enhance our Digital Banking platform, architecting new APIs...
1 week ago
$90K - $110K *
Lead the customer lifecycle by driving onboarding, adoption, and expansion. Utilize AI tools to enhance workflows and deliver value, while building strong relationships and ensuring customer success t...
1 week ago
Senior Field Service Technician
$68K - $109K *
Champion customer satisfaction by executing service work, troubleshooting, and enhancing operational efficiency. Collaborate with teams to deliver quality solutions while ensuring safety and complianc...
1 week ago
Payroll Strategy and Operate Senior Manager
$171K - $338K *
Engage your expertise to lead strategic initiatives in Payroll Operations, guiding clients through process analysis, technology solutions, and team leadership. Drive growth and transformation while en...
1 week ago
Payroll Strategy and Operate Senior Manager
$171K - $338K *
Join a team that's transforming payroll operations by guiding clients through process analysis, technology solutions, and strategic planning. Leverage your leadership skills to drive growth and enhanc...
1 week ago
$105K - $135K *
Partner with us to lead comprehensive RFP and proposal processes, crafting persuasive technical content and collaborating with cross-functional teams to enhance our credibility in the healthcare secto...
1 week ago
$100K - $140K *
Empower global business practices by leading diverse project teams in innovative industries. Collaborate with stakeholders to ensure project success through effective management and integration of cut...
Reposted 1 week ago
$115K - $130K *
Lead the Archibus platform for a major Life Sciences client, driving enhancements and integrations while ensuring data integrity and user satisfaction. Collaborate with cross-functional teams to optim...
1 week ago
ServiceNow Business Systems Developer
$134K - $183K *
Champion automation excellence by designing and implementing ServiceNow solutions that enhance ITSM and operational efficiency across enterprise environments, driving innovation and seamless integrati...
1 week ago
Senior Strategic Financial Analyst
$110K - $140K *
Lead the development of financial forecasts and models, ensuring alignment with strategic goals. Collaborate with cross-functional teams to enhance financial processes and drive insights that support...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.