Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Mechanical Engineer | Chiller Systems
$95K - $115K *
Advance your career by developing cutting-edge marine chiller systems. Lead engineering projects, innovate HVAC&R solutions, and collaborate on product design to meet commercial and defense needs whil...
Reposted 1 week ago
Senior Test Engineer - Systems
$93K - $125K *
Join us as a Senior Test Engineer to lead the planning and execution of complex product testing, utilizing your expertise to assess performance criteria across various systems while collaborating with...
Reposted 1 week ago
Senior Pricing Analyst - Material Cost Estimator
$79K - $103K *
Transform cost estimation processes by collaborating with multifaceted teams to deliver precise material pricing for DoD proposals, ensuring compliance and competitiveness while supporting strategic d...
Reposted 1 week ago
Senior Director, Alliance Management
$242K - $290K *
Empower strategic partnerships by managing alliances, driving collaboration, and ensuring alignment with organizational goals. Leverage your expertise to foster trust and deliver impactful outcomes in...
1 week ago
$95K - $115K *
Manage progress at construction sites, ensuring adherence to safety, schedule, and quality standards while overseeing craft and subcontractor performance for successful project execution...
Reposted 1 week ago
Professional Services Engineer - Remote
$110K - $160K *
Optimize customer networks while delivering integrated networking and cybersecurity solutions. Collaborate globally, enhance performance, and ensure satisfaction as you tackle complex challenges in an...
Reposted 1 week ago
$100K - $120K *
Lead the monthly close and day-to-day accounting operations, ensuring accuracy and efficiency as the business scales. Collaborate with cross-functional teams to enhance processes and implement automat...
1 week ago
Senior Strategist, Paid Search (DTC)
$85K - $106K *
Empower clients by leading innovative paid search strategies across diverse categories. Collaborate with cross-functional teams to drive performance, optimize campaigns, and connect search tactics to...
1 week ago
Senior Talent Acquisition Specialist
$90K - $100K *
Unlock potential by spearheading talent acquisition strategies and cultivating relationships with leadership. Drive recruitment across various functions while mentoring teams to build a pipeline of to...
Reposted 1 week ago
Enterprise Principal Architect
$150K - $180K *
Lead the charge in shaping architectural design and integrity of core systems. Collaborate with senior leaders to set technical direction, evaluate new technologies, and resolve complex issues, paving...
1 week ago
$80K - $95K *
Lead the implementation of safety programs across multiple wind and solar project sites, ensuring compliance and promoting a safe work environment for all team members and contractors. Collaborate wit...
Reposted 1 week ago
Lead Actuarial Predictive Modeler
$110K - $130K *
Optimize predictive modeling initiatives by designing and implementing advanced actuarial pricing models. Collaborate with cross-functional teams to ensure compliance and drive strategic pricing solut...
1 week ago
Senior Actuarial Predictive Modeler
$95K - $115K *
Drive impactful pricing strategies by developing predictive models that enhance segmentation and lifetime value. Collaborate with cross-functional teams to ensure compliance and deliver high-quality a...
1 week ago
Director of Recruitment and Talent Development
$90K - $125K *
Lead recruitment and talent development initiatives to attract top legal professionals, enhance performance evaluations, and implement HR policies, fostering a culture of excellence and collaboration...
1 week ago
Territory Manager - Glaucoma - Central
$90K - $140K *
Unlock potential by driving growth and adoption of innovative surgical glaucoma technology. Collaborate with surgeons and staff to deliver exceptional support and education, while building sustainable...
Reposted 1 week ago
Environmental, Health and Safety Manger - Distribution Warehouse
$80K - $105K *
Champion safety initiatives across multiple locations, enhancing EHS programs and training while collaborating with operations to ensure compliance and continuous improvement in a dynamic industrial e...
1 week ago
21GRAMS- Creative Director, Copy
$200K - $220K *
Drive impactful healthcare advertising by leading creative teams, overseeing brand strategies, and ensuring high-quality copy and art execution. Collaborate across departments to foster innovation and...
1 week ago
VP OF SALES - EAST COAST - HEALTHCARE
$160K - $200K *
Empower your career by leading a high-performing sales team to drive profitable growth in the healthcare sector. Develop and execute strategic sales initiatives, foster client relationships, and ensur...
Reposted 1 week ago
$180K - $220K *
Optimize revenue and profitability as you lead commercial finance, drive pricing strategies, and negotiate pivotal agreements with stakeholders, playing a vital role in shaping financial success acros...
Reposted 1 week ago
Senior Engineering Manager - GTM
$239K - $298K *
Discover a pivotal role in shaping the future of our engineering function. Lead a small team to enhance our GTM engine, integrating product and marketing efforts while driving innovation in technology...
1 week ago
$80K - $95K *
Drive your career with impactful first-line support for flight simulator software, troubleshooting hardware, and collaborating with cross-functional teams to enhance customer experience and resolve te...
Reposted 1 week ago
Division Vice President IT and Digital Transformation- Aerospace & Defense Division
$225K - $250K *
Lead the charge in pioneering technology strategies that enhance operational excellence and drive innovation across multiple business units. Partner with leaders to implement advanced solutions in AI...
Reposted 1 week ago
$110K - $145K *
Partner with us to drive sales growth and elevate client relationships. Utilize tailored product demos and consultative techniques to enhance customer satisfaction and revenue, while leveraging your e...
Reposted 1 week ago
Marketing Manager - Operations
$88K - $105K *
Transform your career by leading strategic marketing initiatives that enhance brand visibility and drive revenue growth. Collaborate with cross-functional teams to create compelling content and optimi...
1 week ago
Supervisory Criminal Investigator (Special Agent in Charge)
$100K - $120K *
Lead strategic planning and execution of investigative programs, ensuring alignment with organizational goals. Oversee multiple units, manage resources, and provide guidance to enhance operational eff...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.