Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$100K - $120K *

Optimize your recruiting expertise to attract top technical talent. Collaborate with engineering leaders to enhance hiring strategies and deliver an exceptional candidate experience while championing...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$108K - $130K *

Manage and optimize the National Reconditioning Center's logistics and repair operations for complex electronic systems, ensuring effective integration and support for NWS programs while providing str...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $140K *

Unlock potential by driving growth in the Level Measurement Solutions sector. Build and maintain strategic client relationships, conduct impactful sales presentations, and collaborate across teams to...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Transform our sales strategy by leading a high-performing team to drive revenue growth, enhance customer engagement, and expand market presence in the North American TEST business. Collaborate cross-f...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Lead regional sales efforts by developing strategic plans, managing high-performing teams, and strengthening client relationships to drive revenue growth and market penetration effectively...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $110K *

Unlock advanced analytics capabilities by leading data science initiatives that drive informed decision-making and operational efficiency in a regulated environment. Collaborate with stakeholders to d...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $115K *

Engineer innovative power interconnect solutions by collaborating with customers and internal teams. Drive technical discussions, translate architecture needs, and support product development to enhan...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $326K *

Grow your career with a strategic role driving Data & AI Security channel sales. Collaborate with partners to develop scalable practices, enhance revenue, and shape go-to-market strategies while engag...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $190K *

Drive your career with a dynamic role focused on digital advertising strategy, optimizing B2B client acquisition through Google PPC. Collaborate across teams to enhance performance marketing, leveragi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that's dedicated to driving sales success through strategic planning, team development, and strong leadership. Collaborate with sales reps to achieve goals and foster a positive work envir...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Drive growth by managing strategic accounts, developing new business, and nurturing relationships within your territory. Collaborate with teams to ensure client satisfaction and achieve sales targets...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $95K *

Transform workplace dynamics by managing employee and labor relations, conducting investigations, and ensuring compliance with labor laws. Collaborate with management to foster a fair and productive e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$150K - $180K *

Engage with C-suite leaders to drive strategic sales for a compliance platform. Lead full sales cycles, develop account strategies, and leverage AI tools to enhance client relationships and achieve re...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$109K - $175K *

Champion a pivotal role bridging scientific and commercial teams, driving Spatial Proteomics sales through customer engagement, KOL relationships, and market activation. Leverage scientific expertise...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $160K *

Transform store operations by leading a high-performing team, enhancing customer experiences, and driving sales growth while ensuring safety and operational excellence in a fast-paced automotive servi...

1 week ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Take ownership of complex ERP solutions by analyzing business processes, designing customizations, and leading integration efforts to optimize performance and ensure data integrity across systems whil...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $250K *

Advance your career as a patient-focused Associate Dentist in a supportive practice, utilizing modern technology and clinical freedom to deliver exceptional care while contributing to a growing team d...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$230K - $290K *

Pioneer the future of checkout experiences by leading frontend engineering initiatives. Collaborate across teams to set technical strategies, enhance operational processes, and foster a culture of qua...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$170K - $200K *

Shape the future of finance transformation by prioritizing systems requests and process improvements. Collaborate across teams to enhance operations and drive impactful change in a fast-paced, dynamic...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$235K - $270K *

Join a team that's driving access strategy across the Northeast, managing key payer relationships and ensuring launch readiness for rare disease therapies. Collaborate with cross-functional teams to o...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Deliver exceptional sales performance by managing territory relationships and driving growth through effective product promotion and client engagement in the electrical industry...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Champion the development of Planning and Inventory strategies, leading a team to optimize supply chain performance and ensure compliance. Drive process improvements and manage supplier relationships t...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in optimizing physical therapy operations, enhancing care quality and access through strategic resource allocation and team development. Collaborate across clinical functions to drive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$200K - $240K *

Unlock potential by leading performance marketing initiatives to drive qualified customer acquisition through innovative digital strategies and collaboration with cross-functional teams...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.