Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$88K - $105K *
Engage in comprehensive finance integration for acquired companies, ensuring accurate data mapping, system conversion, and post-close stabilization. Collaborate with cross-functional teams to streamli...
1 week ago
$130K - $160K *
Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...
1 week ago
Principal Software Engineer, Workload Orchestration (Distributed Compute))
$165K - $215K *
Architect innovative solutions to complex technical challenges, driving platform direction and enabling deep specialists. You'll tackle high-leverage problems that define our future capabilities and e...
1 week ago
Senior Expert Engineer Industrial Services
$149K - $205K *
Contribute to engineering compliance by leading audits and assessments across North American factories. Drive standardization, mitigate risks, and enhance regulatory adherence while collaborating with...
1 week ago
$95K - $137K *
Contribute to marketing strategies and brand goals by leading projects across consumer communications and product innovation, while inspiring cross-functional teams to execute effectively and efficien...
Reposted 1 week ago
$75K - $99K *
Empower production efficiency by supervising teams and driving continuous improvement. Oversee scheduling, quality compliance, and safety for optimal output and equipment maintenance while fostering e...
Reposted 1 week ago
$143K - $190K *
Lead the charge in delivering scalable digital solutions by establishing standards and practices across teams and vendors. Drive performance management and integrated planning to ensure successful pro...
1 week ago
Mechanical Engineer II - Thermal Systems
$80K - $95K *
Redefine the HVAC&R industry by developing innovative products for commercial and defense markets. Collaborate on testing and analysis, support design tasks, and provide thermodynamic insights to driv...
Reposted 1 week ago
Pricing & Promotion Lead - US Remote
$85K - $144K *
Engineer comprehensive pricing strategies that maximize revenue and profitability while leveraging data analytics and automation tools. Collaborate with cross-functional teams to establish pricing fra...
Reposted 1 week ago
Vice President (General Contracting)
$150K - $180K *
Pioneer sustainable growth by leading strategic initiatives, strengthening client relationships, and enhancing operational excellence in commercial construction. Drive performance and cultivate top ta...
Reposted 1 week ago
Business Development Manager - Transactional Division
$110K - $120K *
Engage and drive regional growth for comprehensive due diligence services in the Midwest. Build strategic relationships with key stakeholders in commercial real estate, delivering actionable insights...
Reposted 1 week ago
Senior Engineering Consultant - Equity Due Diligence
$110K - $130K *
Unlock potential by leading complex commercial real estate due diligence projects. Collaborate with multidisciplinary teams to provide technical guidance and client leadership, ensuring high-quality d...
1 week ago
Senior Director of Community Programs and Shelter Plus Care
$90K *
Take ownership of community outreach initiatives, leading diverse programs to enhance housing and recovery services. Cultivate partnerships, inspire teams, and drive innovative solutions to improve li...
Reposted 1 week ago
Traveling General Superintendent - Justice
$100K - $120K *
Take ownership of complex construction projects in the justice sector, overseeing management, safety, and quality assurance while leading diverse teams to successful completion and lasting impact...
Reposted 1 week ago
$80K - $95K *
Manage complex low voltage construction projects, ensuring quality, safety, and budget adherence. Collaborate with trade partners and oversee execution while developing efficient workflows to deliver...
Reposted 1 week ago
Director Commercial Execution USA - Digital Health (Silent Cloud)
$162K - $203K *
Join a team that's transforming digital tinnitus care in the U.S. by leading commercial execution across healthcare sectors. Drive adoption and optimize partnerships to enhance patient engagement and...
Reposted 1 week ago
$90K - $110K *
Drive growth by leading sales and technical initiatives in heating and combustion solutions across the Southeast Region, fostering relationships with key clients and internal teams to achieve strategi...
1 week ago
Senior Security Engineer, Corporate Security
$186K - $218K *
Architect robust security solutions to safeguard corporate infrastructure and user devices. Collaborate with IT and engineering teams to identify risks and implement effective security measures, ensur...
1 week ago
Regional Manager Payor Accounts - Midwest
$140K - $185K *
Accelerate your career by executing regional payor strategies to secure coverage and reimbursement for innovative Surgical Glaucoma products. Collaborate with cross-functional teams and build relation...
Reposted 1 week ago
Enterprise Cybersecurity Manager
$101K - $158K *
Lead enterprise-wide cybersecurity initiatives, aligning operations and compliance with strategic goals. Drive actionable security plans, manage risks, and enhance capabilities while fostering a high...
1 week ago
Optometrist-St. Louis, MO-LensCrafters
$100K - $120K *
Elevate patient care by joining a dynamic optometry practice, where you'll enjoy professional autonomy and flexible scheduling while utilizing advanced technology to provide exceptional eye care servi...
1 week ago
Physical Security - Facilities Lead
$163K - $203K *
Elevate security standards by leading classified design and accreditation for defense facilities. Collaborate with cross-functional teams to ensure compliance and streamline processes for rapid deploy...
1 week ago
Associate Chief Financial Officer
$204K - $216K *
Lead the charge in enhancing compliance operations and financial oversight for multi-billion-dollar loan and grant programs, ensuring sound accounting practices and providing expert guidance to senior...
1 week ago
On Premise Specialist - San Francisco
$90K - $95K *
Join a team that's driving brand visibility and growth in the on-premise channel. As an On-Premise Specialist, you'll manage key accounts, optimize sales strategies, and collaborate with distributors...
Reposted 1 week ago
Business Operation and Data Intelligence Manager
$110K - $130K *
Reimagine operational excellence by integrating data intelligence and insights across multiple business functions. This role enhances strategic decision-making, optimizes workflows, and supports marke...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.