Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $116,335
Oracle HCM Technical Architect
$120K - $145K *
Transform client experiences by leading the design and implementation of Oracle HCM Cloud solutions. Collaborate with teams to ensure scalable, reliable, and high-performance technical architectures t...
Reposted today
Oracle HCM Principal Consultant- Core HR
$110K - $130K *
Drive successful Oracle Cloud HCM implementations by leading Core HR solutions, collaborating with stakeholders, and ensuring best practices for HR operations. Provide functional leadership and mentor...
Reposted today
$95K - $150K *
Join a team that's dedicated to empowering small businesses with tailored security solutions. Collaborate with clients to understand their needs and deliver innovative products, while building lasting...
Today
Director, Software Engineering, Healthcare Interoperability
$180K - $215K *
Lead a dynamic team to innovate and enhance healthcare technology solutions. Drive cross-functional collaboration, mentor engineers, and ensure high-quality software delivery while aligning with strat...
Today
Senior Oracle HCM Consultant (Time & Labor and Absence Lead)
$110K - $130K *
Join a team that's transforming the future of HR by providing expert Oracle Cloud HCM consulting. Lead implementations, mentor clients, and drive innovative solutions across diverse industries while e...
Today
Customer Success Manager, Commercial Accounts
$160K - $180K *
Reimagine customer success by driving onboarding, adoption, and renewals for a diverse portfolio. Collaborate with cross-functional teams to ensure every user thrives, turning initial deployments into...
Reposted today
$211K - $272K *
Transform your career by leading enterprise applications strategy and delivery. Collaborate with cross-functional teams to enhance processes, drive AI adoption, and ensure robust application architect...
Reposted today
$95K - $150K *
Drive your career forward by providing tailored security solutions to small businesses. Collaborate with owners to understand their needs, customize systems, and cultivate lasting relationships while...
Today
Project Manager - Power (Multiple Locations)
$140K - $460K *
Lead the charge in managing complex energy storage projects, driving innovative solutions in renewable energy. Collaborate with multi-disciplinary teams to ensure project success from development to e...
Today
Project Procurement Manager - Construction (Kansas City)
$95K - $115K *
Join a team that's optimizing procurement strategies to enhance operational efficiency across multiple projects. Leverage supplier relationships and manage negotiations to drive performance and cost s...
Reposted today
$150K - $180K *
Empower your career by leading innovative GTM engineering initiatives. Drive AI workflows, automate marketing processes, and enhance productivity across teams. Collaborate with stakeholders to transfo...
Reposted today
Associate Director/Director, Clinical Program Management
$135K - $160K *
Advance clinical trial execution by leading cross-functional teams, ensuring timely delivery of innovative therapies. Collaborate with stakeholders to navigate product life cycles from concept to comm...
Today
$160K - $180K *
Drive the product metrics operating system, managing quarterly planning, release cycles, and customer feedback integration. Collaborate with product managers to ensure alignment between roadmap work a...
Today
VP, IT Strategy & Business Alignment, Innovation
$175K - $210K *
Drive enterprise technology strategy and innovation, aligning IT with business goals. Lead strategic planning, vendor management, and financial oversight to enhance operational performance and support...
Today
$153K - $225K *
Drive the design and execution of impactful sales programs that enhance pipeline generation and revenue outcomes. Collaborate cross-functionally to ensure alignment and accountability, while operating...
Today
Regional Sales Director - Milwaukee
$180K - $215K *
Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...
Reposted today
Senior Manager, Performance and Quality
$67K - $182K *
Unlock your potential as you lead proposal development and client audit responses, ensuring clarity and compliance in complex healthcare contracts. Drive project management for implementations while c...
Today
Regional Sales Director - Phoenix
$180K - $215K *
Transform regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability an...
Reposted today
Regional Sales Director - Austin
$180K - $215K *
Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...
Reposted today
Senior Medical Science Liaisons (MSL) - Cardiovascular, Arizona
$215K - $240K *
Elevate your career by engaging with key opinion leaders and healthcare professionals. This role focuses on scientific collaboration and strategic partnerships, driving impactful medical insights with...
Reposted today
Regional Sales Director - Washington D.C.
$180K - $215K *
Shape the future of healthcare by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster s...
Reposted today
BDM (Affiliates & Partnerships) USA
$100K - $120K *
Join a team that's redefining partnerships in the crypto and fintech space. You'll engage with key affiliates and networks, driving growth through live negotiations and strategic collaborations, all w...
Reposted today
Senior Application Security Engineer
$110K - $130K *
Join our Cyber Security team to spearhead a robust application security program, collaborating with developers to secure software and mitigate vulnerabilities. Help innovate security tools while enhan...
Reposted today
$85K - $100K *
Transform veterinary care by joining a dynamic team offering flexible scheduling options. Contribute to two growing hospitals, providing high-quality medical and surgical services while enjoying a sup...
Reposted today
Workday Business Solutions Analyst
$88K - $138K *
Drive cross-functional projects by translating business needs into technical requirements, ensuring successful adoption of solutions across various People Technology platforms, including Workday and T...
Reposted today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.