Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Information Technology (IT) Business Partner
$148K - $201K *
Transform IT services by developing strategic partnerships and delivering innovative solutions that enhance business performance and production capabilities within the Defense, Space & Security divisi...
6 days ago
Experienced Procurement Agent (Precision Engagement Systems)
$88K - $109K *
Join a team that's redefining procurement strategies in a dynamic environment. Leverage your expertise in supplier management and contract negotiation to drive performance and innovation in our Precis...
6 days ago
Experienced Estimating and Pricing Specialist
$93K - $126K *
Optimize pricing strategies and cost proposals by leveraging your expertise in estimating, financial analysis, and compliance. Collaborate with cross-functional teams to enhance accuracy and drive suc...
6 days ago
Data Acquisition Specialist – CPG Purchase Data
$80K - $95K *
Join us to manage and enhance our consumer purchase data assets, collaborating with vendors and internal teams to ensure high-quality data acquisition and compliance, driving insights and analytics fo...
6 days ago
Business Development Manager – Gas Piping Systems
$76K - $180K *
Innovate in business development by driving growth for gas piping systems. Lead strategies to enhance contractor demand and expand wholesale distribution, translating market insights into measurable r...
6 days ago
BIM/VDC Engineering Services Specialist
$57K - $108K *
Engage in innovative BIM/VDC projects, delivering precise drafting services and managing multiple tasks in a dynamic environment. Collaborate with clients to create detailed piping drawings and advanc...
6 days ago
$124K - $149K *
Grow your career with us as you design and enhance security infrastructure across AWS and on-premises environments, ensuring robust protection for critical workloads through innovative cloud security...
6 days ago
HPC (High-Performance Computing) Service Delivery Manager
$149K - $201K *
Lead the delivery and optimization of high-performance computing services, ensuring reliability and compliance while managing client relationships and operational issues. Drive continuous improvement...
6 days ago
$147K - $199K *
Contribute to dynamic frontend engineering, driving strategic direction and leading the development of user-centered web applications for government clients. Harmonize technical excellence with a stro...
Reposted 6 days ago
$102K - $138K *
Unlock potential by leading major incident management to enhance healthcare IT operations. Collaborate with cross-functional teams to ensure system stability and improve patient care across diverse me...
6 days ago
Medicaid Business Operations Program Director
$161K - $218K *
Lead the charge in healthcare operations, ensuring program success and financial performance while collaborating with stakeholders to adapt to evolving needs. Drive high-performance teams and deliver...
Reposted 6 days ago
ICAM Project Manager – Identity Governance & Administration (IGA)
$131K - $178K *
Transform enterprise identity governance by leading IGA projects, ensuring timely delivery and alignment with mission needs. Collaborate across teams to enhance security and compliance in a dynamic IC...
6 days ago
Senior Power Platform Administrator
$79K - $108K *
Join a team that's transforming technology into opportunity by administering and governing Microsoft Power Platform environments. Leverage your expertise to enhance mission-critical projects and drive...
6 days ago
$97K - $115K *
Transform technology into opportunity by developing innovative SharePoint solutions. Lead the charge in enhancing user experiences and integrating Microsoft 365 services while collaborating with cross...
6 days ago
Information Systems Security Engineer
$113K - $154K *
Shape the future of cybersecurity by leading the modernization of critical systems. Utilize AI tools and collaborate with teams to implement robust security measures, ensuring compliance with federal...
6 days ago
Senior SharePoint Administrator
$79K - $108K *
Optimize SharePoint environments by administering, configuring, and supporting both SharePoint Server and Online. Collaborate with teams to ensure platform health, security, and compliance while mento...
6 days ago
Committee Engagement Specialist
$85K - $92K *
Lead the charge in managing Safety and Compliance Committee operations, ensuring accurate records, effective onboarding, and seamless collaboration with stakeholders to uphold governance standards and...
Reposted 6 days ago
$102K - $138K *
Lead major incident management efforts to enhance healthcare IT operations, ensuring stability and availability of critical systems. Collaborate with cross-functional teams to resolve high-severity in...
6 days ago
FinOps Cloud Engineer | Active Secret clearance
$129K - $149K *
Unlock your potential as you collaborate with teams to design and optimize cloud solutions, ensuring secure and cost-efficient operations for mission-critical projects. Drive innovation and efficiency...
6 days ago
Principal Palo Alto Networks SME
$153K - $207K *
Lead the design and optimization of advanced network security architectures, focusing on Palo Alto Networks solutions. Provide senior technical leadership, drive enterprise-scale implementations, and...
6 days ago
Senior Backend Engineer - Microservices
$131K - $178K *
Develop and support scalable microservices for enterprise systems, collaborating with product and engineering teams to ensure high-quality delivery within a cloud-native platform, while mentoring and...
Reposted 6 days ago
ICAM Project Manager - Enterprise Identity Services
$131K - $178K *
Join a team that's driving identity data management initiatives, ensuring accurate aggregation and synchronization of identity and entitlement data across diverse environments. Lead project delivery a...
6 days ago
Senior Manager, Family Office Outsourcing
$108K - $189K *
Unlock potential by leading a team handling diverse Family Office clients. Drive client success through high-quality financial reporting, talent development, and collaborative processes, ensuring a su...
Reposted 6 days ago
$85K - $100K *
Lead the charge in revenue accounting excellence, ensuring compliance with ASC 606 while driving process improvements and delivering insightful financial analyses to stakeholders across the organizati...
6 days ago
Sales Specialist Manager, Loyalty Issuers
$100K - $143K *
Elevate your career by driving loyalty solutions sales within the financial services sector. Leverage your expertise to build relationships, execute strategies, and secure multimillion-dollar deals wh...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.