Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Regional Director of Agent Channel - Atlanta
$110K - $130K *
Champion strategic partnerships and drive revenue growth through effective channel management and collaborative business planning, ensuring sales success and partner satisfaction while navigating comp...
Reposted 5 days ago
$120K - $247K *
Unlock potential by leading complex digital production across diverse platforms, ensuring seamless execution of business and creative strategies. Collaborate with cross-functional teams to deliver imp...
5 days ago
Sr. Adobe Experience Platform (AEP) Engineer
$96K - $166K *
Lead the enhancement and scaling of Adobe Experience Platform solutions, ensuring optimal data governance and architecture across digital ecosystems. Collaborate with cross-functional teams to achieve...
Reposted 5 days ago
Sr. Account Manager - State Government (Northeast)
$114K - $218K *
Transform customer relationships and lead enterprise sales initiatives while driving innovative GIS solutions in state government markets. Collaborate with teams to meet revenue goals and foster profe...
Reposted 5 days ago
$160K - $210K *
Transform healthcare communications by strategizing and executing impactful media outreach, building relationships, and crafting compelling narratives that resonate with consumers and industry leaders...
Reposted 5 days ago
$135K - $160K *
Shape the future of secure, scalable backend systems as a hands-on leader. Design and guide a team while writing Golang code for critical distributed services serving millions. Drive performance and p...
Reposted 5 days ago
Sr Technical Program Manager, Data
$120K - $145K *
Join a team that's redefining enterprise data management by leading cross-functional initiatives, ensuring data reliability, and driving strategic insights through advanced program management and tech...
5 days ago
Senior Director, Analytical Development
$230K - $280K *
Champion analytical development by leading strategy and execution for pipeline products. Drive compliance and quality control while building a high-performing team in a dynamic environment focused on...
5 days ago
Lead Counsel, Commercial and Marketing, APAC and Americas
$236K - $270K *
Drive commercial legal strategies across APAC and the Americas, partnering with cross-functional teams to support growth. Leverage extensive experience in B2B transactions and marketing law to provide...
5 days ago
Remote - Account Executive (Healthcare Provider Solutions)
$150K - $200K *
Grow your career with a dynamic role focused on driving new business in the healthcare provider space. Leverage your sales expertise to exceed quotas, engage decision-makers, and collaborate with inte...
5 days ago
Psychiatric Mental Health Nurse Practitioner (PMHNP)
$181K - $233K *
Shape the future of mental health care by delivering exceptional patient support as a Psychiatric Mental Health Nurse Practitioner. Enjoy a hybrid work model, competitive compensation, and a collabora...
5 days ago
Clinical Psychiatrist (Outpatient) -Kansas City MO
$350K - $400K *
Transform patient care by providing exceptional outpatient psychiatric services. Collaborate with a dedicated team in a supportive environment, ensuring clinical excellence and work-life balance while...
5 days ago
CPG Marketing Account Director
$110K - $130K *
Shape the future of digital marketing by driving performance through integrated strategies across multiple channels. Lead and mentor high-performing teams while cultivating strong client relationships...
Reposted 5 days ago
$166K - $200K *
Elevate your career as a Chief CRNA, leading a dedicated anesthesia team in a collaborative environment. Enjoy flexible scheduling, high autonomy, and a supportive culture while providing exceptional...
5 days ago
$170K - $200K *
Drive exceptional anesthesia care in a modern outpatient setting while enjoying autonomy and a predictable schedule. Collaborate closely with a skilled team in a physician-led environment focused on h...
Reposted 5 days ago
$170K - $200K *
Lead the charge in delivering exceptional anesthesia care for outpatient GI procedures, enjoying a high degree of autonomy without the demands of night, weekend, or holiday shifts. Join a supportive...
Reposted 5 days ago
SAP Project Scheduler - 100% onsite in St. Louis, MO
$72K - $132K *
Accelerate progress at large SAP projects by developing, managing, and maintaining a comprehensive master schedule. Ensure clear communication and timely updates with clients and delivery teams while...
Reposted 5 days ago
SAP ABAP Developer (100% onsite in St. Louis, MO)
$91K - $246K *
Unlock your potential by developing high-quality SAP ABAP solutions. Collaborate with cross-functional teams to translate business needs into technical designs, mentor junior developers, and drive mod...
Reposted 5 days ago
Director, CMS & HHS Business Development
$182K - $250K *
Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...
Reposted 5 days ago
Staff AI Engineer | US | Remote
$154K - $185K *
Lead the charge in developing advanced AI systems and automation platforms. Own multi-agent architectures and backend services that optimize workflows across teams, driving operational efficiency and...
Reposted 5 days ago
Account Executive, Commercial West
$300K - $350K *
Lead the charge in driving enterprise revenue across the West territory, engaging with senior security leaders in regulated industries. Shape strategic sales initiatives and build lasting relationship...
Reposted 5 days ago
Channel Account Manager, DIB/MSSP
$215K - $235K *
Lead the charge in building a robust partner ecosystem for defense contractors, driving revenue through MSSPs, MSPs, RPOs, and C3PAOs. Own partner recruitment, enablement, and success, while collabora...
Reposted 5 days ago
Salesforce Higher Ed Solution Architect
$120K - $145K *
Transform higher education through innovative Salesforce solutions, guiding institutions in architecture design, implementation, and best practices to enhance student engagement and operational effici...
Reposted 5 days ago
Technical Account Manager, Commercial
$130K - $160K *
Join a team that's dedicated to optimizing customer success through technical expertise. As a trusted advisor, you'll manage relationships, guide deployments, and ensure seamless adoption for federal...
Reposted 5 days ago
Enterprise Architect - Oracle CX, ERP, HCM & SCM
$135K - $160K *
Lead enterprise architecture strategy across Oracle CX, ERP, HCM, and SCM Cloud. Collaborate with stakeholders to develop scalable solutions, ensuring alignment with business capabilities and technolo...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.