Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Manager, Operational Foundations
$130K - $168K *
Champion strategic initiatives to scale partner operations, leading a global team to drive growth and enhance capabilities through effective execution and collaboration across functions...
Reposted 3 days ago
Manager, Commercial Insights and Strategy
$144K - $222K *
Contribute to data-driven marketing strategies by analyzing insights, guiding teams, and identifying growth opportunities in pharma. Collaborate with leadership to enhance analytics capabilities and d...
3 days ago
$100K - $120K *
Champion comprehensive dental care by delivering services and education, overseeing dental staff, and enhancing patient health in a community-focused environment while adhering to best practices and r...
Reposted 3 days ago
$100K - $120K *
Lead the charge in transforming employer benefits by driving sales growth in the Mid-Atlantic region. Collaborate with teams to manage client relationships and contribute to product development while...
3 days ago
AI Quality Analyst, AI & Innovation
$80K - $95K *
Take ownership of AI quality assurance by ensuring the accuracy and reliability of AI data extraction processes. Collaborate with stakeholders to maintain ground-truth datasets and enhance evaluation...
3 days ago
$120K - $190K *
Unlock potential by leading the design and integration of advanced satellite communications systems. Drive system architecture, manage requirements, and collaborate across multi-disciplinary teams to...
Reposted 3 days ago
$150K - $180K *
Drive impactful financial solutions by leading teams and transforming data into strategic insights. Collaborate with stakeholders to enhance processes and deliver high-quality results that support inf...
3 days ago
Head of Technology Foundations
$160K - $200K *
Join a team that's redefining technology foundations to empower innovation. Lead the strategy and operations of core infrastructure, driving modernization and automation while collaborating with engin...
3 days ago
$135K - $175K *
Transform the sales landscape by driving growth through proactive prospecting, relationship building, and closing deals in the home improvement sector. Join a dynamic team focused on achieving targets...
3 days ago
Media Activation (Partner Media) Director, Partner Media
$110K - $130K *
Join a team that's driving innovative media strategies and partnerships. Oversee planning and execution of media investments across diverse channels, ensuring alignment with client objectives while fo...
Reposted 3 days ago
Customer Business Development Manager, D2C Dietary Supplements - West Coast
$132K - $150K *
Drive growth by building relationships with emerging dietary supplement brands, connecting customer ambitions with innovative solutions, and advancing projects from concept to commercialization across...
3 days ago
$120K - $173K *
Join us to build a robust Product Intelligence function, transforming complex data into actionable insights. You'll define key questions, create data infrastructure, and influence product decisions, s...
3 days ago
$125K - $150K *
Support client development efforts by providing Hogan IDS expertise. Collaborate on technical design, coding, and testing while ensuring smooth production migration. Leverage your extensive experience...
3 days ago
Account Director - US Remote (Ideally NYC)
$150K - $200K *
Elevate your career by leading a $3M-5M client portfolio, driving strategic initiatives and fostering strong relationships. Collaborate with diverse teams to deliver exceptional results while managing...
3 days ago
Urgent Care Nurse Practitioner Specialty Care - Jefferson City, MO (Dual Posted with Job ID: 61613)
$115K - $131K *
Grow your career with a dynamic Urgent Care team, providing exceptional patient care in a fast-paced environment. Leverage your clinical expertise to enhance healthcare experiences and ensure patient...
3 days ago
$87K - $128K *
Engage in strategic brand development and campaign execution, translating marketing strategies into impactful creative work. Collaborate across teams to enhance employee and member experiences through...
3 days ago
Lead Sales Enablement Program Manager
$119K - $169K *
Elevate customer engagement by shaping compelling narratives for high-value opportunities. Collaborate with Sales and cross-functional teams to create memorable experiences that clearly communicate va...
3 days ago
$80K - $120K *
Champion customer solutions by developing technical expertise across platforms, integrations, and operational processes. Collaborate with teams to resolve issues and ensure successful implementations...
3 days ago
Technical Product Manager - Salesforce CRM Platform
$120K - $145K *
Transform the Salesforce CRM platform by driving strategy, enhancements, and adoption, while leading cross-functional collaboration to deliver user-centric solutions that elevate customer engagement a...
Reposted 3 days ago
Physicians - Acute Care Advanced Care Practitioner
$90K - $110K *
Empower patient care by delivering high-quality outpatient services, collaborating with care teams, and ensuring accurate documentation while engaging with the community to promote health initiatives...
Reposted 3 days ago
$110K - $130K *
Unlock potential by leading client operations and driving revenue cycle improvements. Foster relationships, influence decisions, and ensure performance excellence while collaborating with stakeholders...
3 days ago
Governance & Securities Specialist, United States
$80K - $95K *
Shape the future of corporate governance by executing compliance workflows, managing documentation, and supporting senior legal professionals in a dual-listed public company environment, ensuring time...
3 days ago
$85K - $127K *
Seeking a skilled analytics manager to lead commercial data analysis, develop reporting solutions, and support pricing decisions. Collaborate cross-functionally to drive insights and enhance team perf...
Reposted 3 days ago
Senior Public Relations Manager, Financial Communications
$180K - $210K *
Transform financial communications by crafting compelling narratives that enhance investor understanding and media relations. Collaborate with cross-functional teams to elevate corporate strategy and...
3 days ago
$80K - $95K *
Transform packaging design strategies by bridging regulatory needs and industry practices. Collaborate with cross-functional teams to develop eco-design tools and resources, ensuring compliance and pr...
3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.