Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Managing Consultant - Value Based Care and Population Health - Healthcare
$125K - $200K *
Shape the future of healthcare by leading value-based care initiatives, managing client engagements, and driving strategic recommendations that enhance quality and reduce costs. Collaborate with diver...
2 days ago
Public Sector Account Director (Southeast)
$110K - $130K *
Lead strategic sales initiatives in the SLED sector, driving revenue growth and building executive relationships. Manage complex sales cycles, mentor junior staff, and represent the company at industr...
2 days ago
$110K - $130K *
Lead the origination and management of ESOP lending relationships, ensuring comprehensive client support, deal structuring, and strategic business development in the commercial banking sector...
Reposted 2 days ago
BIM Designer & Coordinator: Civil
$110K - $130K *
Join a team that's shaping the future of large-scale data center design. Leverage your civil BIM expertise to develop and coordinate complex models, ensuring seamless integration of infrastructure and...
2 days ago
$181K - $226K *
Join a team that's redefining release management by building efficient processes that enhance collaboration between product and engineering. You'll drive operational excellence and ensure timely produ...
2 days ago
$125K - $130K *
Join a dynamic team as a strategic marketing partner, driving growth and market positioning for office advisory services through innovative strategies and compelling narratives...
Reposted 2 days ago
$206K - $257K *
Lead the charge in developing and mentoring a high-performing engineering team, driving collaboration across product and design to enhance our software solutions while fostering a culture of inclusion...
2 days ago
$160K - $180K *
Lead staffing operations by directing recruiting activities and ensuring compliance. Develop metrics for process improvement and manage the recruitment budget while enhancing the employment brand and...
Reposted 2 days ago
$400K - $500K *
Innovate operational excellence by leading global delivery strategies, enhancing client outcomes, and driving profitability. Collaborate with executive teams to shape a scalable, AI-enabled organizati...
2 days ago
Sr Business Analyst Manhattan Scale
$87K - $115K *
Optimize warehouse operations by implementing WMS solutions. Collaborate with teams to enhance workflows, lead testing, and ensure successful deployments, driving efficiency and scalability in logisti...
Reposted 2 days ago
$95K - $115K *
Champion large-scale event production by leading strategic initiatives, managing budgets, and collaborating with clients to create impactful experiences that align with their objectives and engage aud...
2 days ago
Senior Mechanical Engineer - Kiewit Power Engineering
$110K - $130K *
Lead the charge in innovative mechanical design for large-scale power plants, driving projects from concept to completion. Collaborate with a dynamic team to enhance energy solutions and ensure projec...
Reposted 2 days ago
Pharmacy Manager - $150,000 Sign On Bonus and Relocation Available
$100K - $120K *
Transform patient care by providing expert pharmacy consulting and clinical services. Lead a dedicated team to enhance patient experiences, manage pharmacy operations, and ensure compliance with regul...
2 days ago
Pharmacy Manager - $150,000 Sign On Bonus and Relocation Available
$110K - $130K *
Transform pharmacy operations by delivering empathetic consulting services, enhancing patient experiences, and managing staff performance. Oversee medication accuracy, workflow efficiency, and communi...
2 days ago
Payment Integrity Strategic Initiatives Lead
$94K - $130K *
Advance your career by tackling complex business challenges using data insights. Collaborate with stakeholders, lead a team, and drive strategic initiatives to enhance organizational performance and d...
2 days ago
Pharmacy Manager - $150,000 Sign On Bonus and Relocation Available
$112K - $135K *
Drive impactful pharmacy consulting services, enhancing patient care through medication management, immunizations, and clinical services. Lead pharmacy operations, optimize workflow, and foster staff...
2 days ago
$104K - $130K *
Empower growth by transforming complex data into actionable insights. Collaborate with senior leaders to build analytical tools and models that drive strategic decisions, while enhancing operational e...
Reposted 2 days ago
$100K - $120K *
Build and foster strong customer relationships while identifying new business opportunities in the power generation market. Prepare proposals, negotiate contracts, and ensure sales growth through stra...
Reposted 2 days ago
Portfolio Manager - Prediction Markets
$160K - $200K *
Elevate the performance of prediction markets by overseeing strategy, risk management, and team leadership. Drive P&L accountability and collaborate with engineering to enhance infrastructure and mark...
Reposted 2 days ago
Senior Product Manager, AI Workflow Design| US Remote
$115K - $123K *
Empower users by designing intuitive experiences that simplify complex data and workflows. Collaborate with cross-functional teams to deliver accessible, user-centered designs that align with establis...
2 days ago
Senior Technical Program Manager
$130K - $155K *
Manage complex cybersecurity verification programs across large-scale data center projects. Lead coordination among diverse teams, ensuring operational readiness and technical integration throughout c...
Reposted 2 days ago
Electrical Engineer/Designer Team Lead - MEP
$95K - $115K *
Manage and lead a team of electrical designers, ensuring high-quality technical drawings and effective collaboration across disciplines. Drive departmental growth and technical expertise while deliver...
Reposted 2 days ago
$110K - $130K *
Elevate your career by designing and developing scalable cloud-native applications. Leverage your expertise in Java, Spring Boot, React, and Node.js to enhance Workforce Management and Customer Experi...
2 days ago
$116K - $135K *
Lead the charge in enhancing product security for critical defense systems, ensuring compliance with government regulations while managing risks and implementing robust cybersecurity measures througho...
Reposted 2 days ago
Senior Market Strategy & Optimization Consultant
$110K - $176K *
Unlock potential by driving strategic growth initiatives through competitive intelligence and market insights. Collaborate with cross-functional teams to enhance sales effectiveness and client retenti...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.