Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Country Corporate Counsel - US
$142K - $228K *
Join a team that's shaping the future of corporate governance and compliance! In this role, you'll provide strategic legal guidance, mitigate risks, and ensure adherence to laws, driving operational e...
Reposted 2 days ago
Director, Business Development
$312K - $446K *
Lead a high-performing team to drive strategic growth in defense and intelligence markets. Oversee opportunity identification, partner engagement, and pipeline development, ensuring disciplined execut...
2 days ago
$80K - $95K *
Drive building performance and energy efficiency by conducting assessments, audits, and evaluations for diverse properties. Collaborate with clients to enhance sustainability and reduce operational co...
2 days ago
Systems Engineer (Experienced OR Lead)
$121K - $185K *
Lead the charge in the design and optimization of complex systems, ensuring seamless integration and performance to achieve mission success while collaborating with multidisciplinary teams and stakeho...
Reposted 2 days ago
Electrical Engineer/Designer - MEP
$88K - $105K *
Join our dynamic team to design electrical systems for diverse industries, ensuring precision and innovation in every project while collaborating closely with cross-functional teams and clients...
Reposted 2 days ago
$125K - $150K *
Drive channel sales success by defining and executing programs that recruit, activate, and grow Trusted Advisors. Collaborate across teams to enhance performance, communication, and operational effici...
2 days ago
$130K - $200K *
Unlock potential by enhancing our data infrastructure. In this role, you'll own data pipelines, improve performance, and ensure reliable access to analytics across global markets, driving efficiency a...
2 days ago
Security Architect / Security Engineer
$164K - $235K *
Shape the future of security architecture for agentic AI systems by creating and implementing robust, secure solutions that empower innovative applications and ensure data safety in a collaborative, f...
Reposted 2 days ago
$80K - $95K *
Optimize supply chain operations by negotiating IT contracts and fostering collaboration across teams to enhance healthcare delivery and reduce costs. Drive strategic sourcing initiatives while ensuri...
2 days ago
$120K - $145K *
Grow your career with a dynamic engineering team, providing architectural leadership for Java microservices and cloud-native applications while fostering collaboration and continuous growth in a fast...
2 days ago
Senior Director Community Impact
$125K - $150K *
Contribute to a transformative social care strategy that integrates community support into clinical workflows, enhancing patient care and addressing social determinants of health through innovative pa...
2 days ago
Director Net Revenue Management
$125K - $150K *
Lead the charge in optimizing revenue performance by analyzing reimbursement trends, collaborating with teams to resolve discrepancies, and driving strategic initiatives to enhance financial outcomes...
2 days ago
Manager Claims and Litigation HPL PPL GL
$80K - $95K *
Join a team that's dedicated to excellence in risk management by supervising and mentoring a skilled group of Claims Specialists. Drive operational success through performance evaluations and expert g...
2 days ago
Senior Network Architect Security
$120K - $145K *
Shape the future of network security by leading global architecture, optimizing firewall ecosystems, and aligning strategies with cross-functional teams to enhance organizational security standards an...
2 days ago
$159K - $287K *
Drive growth and lead strategic partnerships as you oversee P&L performance and business strategy for key global accounts, ensuring operational excellence and customer satisfaction while managing high...
Reposted 2 days ago
$95K - $115K *
Transform the learner experience by owning business and functional requirements for custom LMS and LCMS platforms. Drive modernization and compliance while collaborating with cross-functional teams to...
2 days ago
Oracle HCM/Payroll Solution Architect Senior Manager/Associate Director
$116K - $140K *
Advance your career as you lead transformative Oracle solutions, architecting scalable designs that drive business value. Collaborate with clients and teams to deliver innovative strategies across HCM...
2 days ago
Head of Enterprise and Strategic Partnerships
$273K - $380K *
Take ownership of building innovative enterprise partnerships that embed financial solutions in leading platforms. Drive strategic deals, capitalize on your industry network, and structure first-of-a...
Reposted 2 days ago
SAP Data Migration Senior Manager - CMT/SemiConductors
$122K - $261K *
Lead the charge in architecting comprehensive SAP data migration strategies for S/4HANA transformations. Drive success through hands-on execution, mentoring teams, and engaging with stakeholders to en...
2 days ago
$80K - $95K *
Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...
Reposted 2 days ago
$100K - $120K *
Shape the future of cloud applications by developing scalable modules and enhancing legacy systems. Collaborate with teams to ensure high-quality code and optimize performance within an Agile framewor...
2 days ago
$118K - $140K *
Join a dynamic team to oversee the implementation and support of enterprise solutions, ensuring quality control and project management excellence while collaborating with clients on technical deployme...
2 days ago
Director of Engineering, Advertiser Experience
$150K - $180K *
Empower engineering teams to innovate advertiser tools, driving technical strategy and delivery while enhancing user experience across self-service and managed workflows in a dynamic ad tech environme...
2 days ago
Traveling Construction Superintendent
$80K - $95K *
Take ownership of field operations, leading construction projects through all phases while ensuring quality, safety, and profitability. Collaborate with teams to tackle challenges and maintain schedul...
Reposted 2 days ago
(Psychiatrist)Outpatient Mental Health Clinics - Assistant Supervisor
$166K - $200K *
Lead the charge in delivering comprehensive mental health services, overseeing clinical operations and team management to enhance patient care and operational efficiency within a dynamic healthcare en...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.