Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Average Salary: $110,967
$180K - $220K *
Lead transformative technology initiatives as a strategic Chief Technology Officer, driving modernization and AI integration while ensuring business continuity and team development in a dynamic softwa...
4 days ago
Sr Manager, Payroll Connection & Integration Support
$135K - $145K *
Lead the charge in optimizing payroll integration operations, managing teams, and driving strategic alignment across functions. Elevate customer experience through data-driven insights and innovative...
4 days ago
Sr. Software Engineer - Stacklok Enterprise
$189K - $231K *
Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...
4 days ago
Director, Market Access - Commercial Coverage & Reimbursement
$187K - $281K *
Redefine market access strategies by leading payer engagement to enhance patient access to genomic testing. Collaborate cross-functionally to drive favorable coverage and reimbursement policies, ensur...
4 days ago
Senior Field Engineer, Data Center Design and Engineering
$320K - $405K *
Transform the future of data center engineering by resolving on-site technical issues, collaborating with contractors, and ensuring project success through effective problem-solving and communication...
4 days ago
$130K - $160K *
Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...
4 days ago
Software Engineer 4/5 - Data and Feature Infrastructure, AI Platform
$466K - $500K+*
Elevate your career by building a cutting-edge ML data platform that enhances productivity for ML practitioners. Collaborate with experts to create innovative solutions for feature computation and sha...
Reposted 4 days ago
Senior Product Manager - Fraud
$200K - $250K *
Champion the evolution of fraud prevention strategies, enhancing customer experience while safeguarding against risks. Collaborate cross-functionally to design innovative solutions that balance securi...
4 days ago
Business Transformation Analyst Sr. - Finance
$95K - $115K *
Inspire enterprise-wide transformation initiatives that enhance growth and innovation. Collaborate across departments to identify opportunities, leverage AI, and apply data-driven insights to drive im...
4 days ago
Medical Director, Utilization Management
$180K - $220K *
Lead the evaluation of outpatient referrals and inpatient admissions for medical necessity, utilizing guidelines and criteria to ensure quality care. Collaborate with providers and mentor UM nurses to...
4 days ago
Dealer Development Manager (Portland, OR)
$80K - $95K *
Join a dynamic team as you develop and maintain dealer partnerships, driving growth and enhancing customer satisfaction in the auto finance sector. Leverage your expertise to navigate market trends an...
4 days ago
$95K - $160K *
Elevate your career by supporting senior leaders in a dynamic tech environment. Manage complex calendars, coordinate travel, and streamline processes to enhance productivity and drive success across g...
4 days ago
$100K - $120K *
Unlock potential by leading a dynamic SQA team to enhance software quality. Drive testing strategies, mentor team members, and ensure compliance with best practices while managing multiple projects in...
4 days ago
$110K - $125K *
Analyze customer needs and drive product initiatives using AI tools. Own features from discovery to delivery, ensuring alignment with business priorities and quality outcomes while collaborating acros...
4 days ago
Director, Consulting & Advisory Alliances, North America
$150K - $170K *
Join a team that's expanding strategic partnerships with consulting firms to enhance supply chain solutions. Drive growth through collaboration, relationship management, and innovative go-to-market st...
4 days ago
$210K - $230K *
Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...
4 days ago
$122K - $205K *
Drive measurable SEO results by owning key surfaces and experiments, leveraging AI tools for hands-on building, and collaborating across teams to enhance organic growth and visibility in a dynamic, re...
4 days ago
Senior Civil Site Designer 1 -- Grid
$77K - $118K *
Lead the design and development of substation and transmission line projects, collaborating with engineers and project teams to deliver high-quality civil site designs and ensure compliance with regul...
4 days ago
$141K - $196K *
Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...
4 days ago
$168K - $232K *
Lead the charge in executing innovative financing strategies for our AI lending marketplace. Collaborate with investors and stakeholders to drive structured transactions, ensuring scalable funding sol...
4 days ago
$78K - $85K *
Build your career in outpatient orthopedic physical therapy, focusing on patient care while enjoying competitive pay, mentorship, and growth opportunities in a supportive environment...
4 days ago
$80K - $90K *
Champion customer success by managing strategic accounts, driving retention, and ensuring satisfaction through effective onboarding and ongoing support. Collaborate with internal teams to achieve cust...
Reposted 4 days ago
Director of Electrical Infrastructure (Heavy Industrial) - REMOTE WORK
$200K - $250K *
Lead the charge in advancing electrical infrastructure services, driving strategic growth and operational excellence across heavy industrial sectors. Foster client relationships and mentor teams to en...
Reposted 4 days ago
$120K - $145K *
Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...
4 days ago
$140K - $160K *
Lead strategic life sciences accounts, driving growth and team development while ensuring project success and client satisfaction through strong relationships and innovative solutions...
4 days ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.