Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,967

Sort By: Relevance

$185K - $315K *

Join us to shape strategic financial planning and analysis, leveraging AI to enhance forecasting and decision-making. This high-impact role collaborates with executives, driving insights that align wi...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $124K *

Champion innovative project management solutions, guiding teams through configuration, product demonstrations, and stakeholder collaboration to deliver value-driven consulting services that adapt to e...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Take ownership of SSP partnerships to optimize programmatic supply, enhance monetization, and ensure compliance. Collaborate with cross-functional teams to drive revenue growth and improve inventory q...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$70K - $110K *

Champion the resolution of complex Tier 3 auto claims, leveraging expertise in investigation, liability assessment, and negotiation to ensure effective outcomes while serving as the primary contact fo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by leading the strategic growth of our Attorney Banking Division. Drive business development, mentor a remote team, and enhance client experiences while achieving personal producti...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $135K *

Shape client relationships and drive growth by expanding existing accounts, identifying service opportunities, and delivering tailored managed security solutions that enhance compliance and risk manag...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$222K - $278K *

Join a dynamic team to drive enterprise sales, transforming industries through innovative technology. Engage with C-level executives, manage complex deals, and build lasting relationships that impact...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $200K *

Lead the innovation and implementation of cutting-edge technology solutions to enhance data governance, optimize operations, and improve workplace experiences while managing a high-performing team of...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$101K - $132K *

Drive impactful media relations and communications strategies to enhance advocacy efforts for Healthy Communities. Collaborate with diverse teams to shape narratives, engage with journalists, and expa...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Elevate your career by leading the development of high-quality clinical documents for global regulatory submissions. Collaborate with cross-functional teams to ensure data-driven messaging aligns with...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of cloud security solutions by leading technical sales pursuits, collaborating with clients and internal teams to deliver tailored compliance strategies and drive successful implement...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Join a team that's driving revenue growth by leveraging strategic relationships and expertise in telecommunications. You'll engage with customers, align solutions to their needs, and lead business dev...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Transportation

$70K - $110K *

Unlock your potential by analyzing data and conducting audits to enhance compliance for innovative B2B and B2C platforms. Collaborate with cross-functional teams, apply critical thinking, and gain ins...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $160K *

Drive high-volume technical recruitment efforts, focusing on specialized roles like Data Scientists and AI Engineers. Collaborate with hiring managers to build strong candidate pipelines and ensure an...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $356K *

Unlock potential by developing innovative AI solutions and enhancing infrastructure capabilities. Collaborate with strategic partners to deliver hands-on technical support, ensuring optimal performanc...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$85K - $111K *

Lead cross-functional teams to design and implement resilient infrastructure solutions. Collaborate with diverse stakeholders to ensure timely delivery of high-quality systems, leveraging automation a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$135K - $145K *

Deliver seamless integration and Tier 3 support for secure mobile infrastructure. Collaborate with enterprise stakeholders to ensure compliance, performance, and customer satisfaction while managing c...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $220K *

Champion innovation in macOS development, driving core sensor features for endpoint protection. Collaborate with a dynamic team to enhance security capabilities, ensuring high performance and reliabil...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$155K *

Transform complex challenges into impactful software solutions. Collaborate with engineers, designers, and justice leaders to drive product strategy and execution, enhancing the criminal justice syste...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Take ownership of software engineering initiatives within established companies. Lead teams, modernize development processes, and enhance code quality while delivering impactful software solutions. Co...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$161K - $190K *

Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$85K - $115K *

Elevate healthcare education by developing evidence-based content for clinicians. Collaborate with experts to create innovative learning materials that address practice gaps and enhance professional s...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.