Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Mississippi

Average Salary in USD

Average Salary: $110,967

Sort By: Relevance

$90K - $110K *

Join a team that's dedicated to ensuring supplier compliance and quality in the nuclear industry. Leverage your expertise in quality assurance to evaluate supplier programs, conduct audits, and mainta...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$146K - $183K *

Empower growth by leading full-cycle executive searches for Director and VP roles, focusing on Engineering, Product, Design, and Data. Collaborate with senior leaders to attract top talent and enhance...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $200K *

Join a team that's dedicated to empowering small businesses through direct sales. This role focuses on prospecting, building relationships, and enrolling new members, driving growth in a dynamic, fiel...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$148K - $248K *

Unlock potential by leading a dynamic team focused on driving growth in financial services. You'll develop strategies, build relationships, and enhance productivity for major institutions, ensuring al...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$93K - $126K *

Elevate your career by supporting diverse system studies in renewable energy projects. Collaborate in a dynamic environment, delivering technical expertise and leveraging advanced tools to ensure safe...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $180K *

Lead staffing operations by directing recruiting activities and ensuring compliance. Develop metrics for process improvement and manage the recruitment budget while enhancing the employment brand and...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $105K *

Lead product marketing initiatives by crafting compelling messaging and strategies that drive customer engagement and adoption. Collaborate cross-functionally to ensure alignment and measure performan...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $150K *

Transform the Salesforce landscape by designing and delivering innovative solutions. Leverage your coding expertise and declarative skills to create scalable applications that meet complex business ne...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Lead the digitization and automation of manufacturing processes, enhancing equipment performance and quality through integration of operational technology and smart systems. Collaborate with cross-fun...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$104K - $108K *

Transform patient care by delivering high-quality acute dialysis services. Collaborate with healthcare teams to ensure optimal outcomes through assessment, planning, and implementation of individualiz...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$330K - $500K *

Shape the future of content discovery by leading product operations and program management. Drive efficiency and innovation across teams, ensuring seamless collaboration and execution of high-impact i...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$200K - $250K *

Optimize your career as a full-stack software engineer, collaborating with agile teams to enhance high-transaction e-commerce applications. Drive quality, mentor peers, and innovate solutions that ele...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in managing diverse capital improvement projects across facilities. Oversee planning, execution, and compliance to ensure safe, efficient delivery while minimizing operational disrupti...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's committed to optimizing production processes and enhancing efficiency through automation. Contribute to quality, cost, and safety improvements while driving continuous enhancements...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive customer success by building relationships, enhancing product adoption, and delivering value in a dynamic SaaS environment. Collaborate cross-functionally to ensure client satisfaction and reten...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $135K *

Unlock potential by leading strategic engagement initiatives for higher education, enhancing perceptions of AP programs. Drive impactful relationships and evaluate outcomes to support student success...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$104K - $174K *

Unlock your potential by developing and implementing advanced analytics and AI solutions. Collaborate with cross-functional teams to translate complex data into actionable insights, driving business a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$73K - $102K *

Unlock potential by developing and deploying Python applications for IT operations, data management, and cloud solutions. Collaborate on data engineering and machine learning projects while adhering t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $102K *

Contribute to the development and maintenance of secure, scalable solutions in Microsoft 365 and Azure. Collaborate with teams to enhance automation, identity security, and API integrations, ensuring...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$122K - $155K *

Unlock potential by bridging business needs with technology solutions in the Microsoft Power Platform. Collaborate with stakeholders to deliver user-friendly, secure, and scalable digital solutions th...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$168K - $310K *

Lead the charge in designing cutting-edge SRAM circuits for next-gen AI chips, optimizing performance and power while collaborating with cross-functional teams to deliver innovative memory solutions a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$59K - $106K *

Transform tactical ISR operations by executing preflight, flight, and post-flight duties. Leverage advanced sensor technology to provide critical analysis and support for diverse missions, ensuring ef...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$211K - $272K *

Transform your career by leading enterprise applications strategy and delivery. Collaborate with cross-functional teams to enhance processes, drive AI adoption, and ensure robust application architect...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by building strategic relationships with athletic associations, leading RFPs, and driving school subscriptions. Own the growth strategy in new states with autonomy to shape processes...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $200K *

Transform clinical research by leading operational oversight of studies, ensuring compliance with protocols and regulations. Collaborate with teams to drive site feasibility, manage budgets, and enhan...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.